Podcast
Questions and Answers
Which of the following mechanisms describes how NSAIDs reduce inflammation?
Which of the following mechanisms describes how NSAIDs reduce inflammation?
- Inhibiting COX enzymes, thus reducing prostaglandin and thromboxane synthesis. (correct)
- Blocking histamine receptors to prevent inflammatory responses.
- Increasing the production of prostaglandins and thromboxanes.
- Stimulating COX enzymes to enhance their activity.
A patient with a history of peptic ulcers is prescribed a non-selective NSAID. Which intervention is most important to discuss with the patient?
A patient with a history of peptic ulcers is prescribed a non-selective NSAID. Which intervention is most important to discuss with the patient?
- The importance of taking the medication on an empty stomach to enhance absorption.
- The benefit of combining the medication with an antacid to reduce its effectiveness.
- The potential increased risk of gastrointestinal bleeding and the need to report any signs. (correct)
- The necessity of increasing fluid intake to prevent kidney damage.
A patient is taking low-dose aspirin daily to prevent cardiovascular events. Which statement accurately describes the mechanism behind this therapy?
A patient is taking low-dose aspirin daily to prevent cardiovascular events. Which statement accurately describes the mechanism behind this therapy?
- Aspirin irreversibly inhibits COX-1, reducing platelet aggregation. (correct)
- Aspirin blocks prostacyclin synthesis to prevent vasodilation.
- Aspirin enhances the production of thromboxane to promote blood clotting.
- Aspirin selectively inhibits COX-2 to reduce inflammation in arteries.
Which of the following NSAIDs is most likely to cause cardiovascular thrombotic events, such as myocardial infarction or stroke?
Which of the following NSAIDs is most likely to cause cardiovascular thrombotic events, such as myocardial infarction or stroke?
A patient with pre-existing renal impairment is prescribed an NSAID. What potential adverse effect should the healthcare provider monitor closely?
A patient with pre-existing renal impairment is prescribed an NSAID. What potential adverse effect should the healthcare provider monitor closely?
Which of the following drug combinations is most likely to increase the risk of GI bleeding?
Which of the following drug combinations is most likely to increase the risk of GI bleeding?
Why are NSAIDs generally avoided during the third trimester of pregnancy?
Why are NSAIDs generally avoided during the third trimester of pregnancy?
Which of the following is an example of a selective COX-2 inhibitor?
Which of the following is an example of a selective COX-2 inhibitor?
A patient taking lithium for bipolar disorder is prescribed an NSAID for arthritis pain. What potential drug interaction should the healthcare provider be aware of?
A patient taking lithium for bipolar disorder is prescribed an NSAID for arthritis pain. What potential drug interaction should the healthcare provider be aware of?
How do NSAIDs affect the effectiveness of antihypertensive medications like ACE inhibitors and ARBs?
How do NSAIDs affect the effectiveness of antihypertensive medications like ACE inhibitors and ARBs?
A patient is prescribed ketorolac for post-operative pain management. What is the primary consideration regarding the duration of ketorolac use?
A patient is prescribed ketorolac for post-operative pain management. What is the primary consideration regarding the duration of ketorolac use?
What is the most important instruction to give a patient who is starting long-term NSAID therapy to minimize the risk of gastrointestinal upset?
What is the most important instruction to give a patient who is starting long-term NSAID therapy to minimize the risk of gastrointestinal upset?
Which laboratory tests are most important to monitor in a patient on long-term NSAID therapy to assess for potential renal toxicity?
Which laboratory tests are most important to monitor in a patient on long-term NSAID therapy to assess for potential renal toxicity?
Which of the following adverse effects is associated with aspirin use that is not typically seen with other non-selective NSAIDs?
Which of the following adverse effects is associated with aspirin use that is not typically seen with other non-selective NSAIDs?
A patient with a known allergy to aspirin is prescribed an NSAID for pain relief. Which of the following actions is most appropriate?
A patient with a known allergy to aspirin is prescribed an NSAID for pain relief. Which of the following actions is most appropriate?
Flashcards
What are NSAIDs?
What are NSAIDs?
Medications with analgesic, antipyretic, and anti-inflammatory effects.
How do NSAIDs work?
How do NSAIDs work?
They inhibit cyclooxygenase (COX) enzymes, reducing prostaglandins and thromboxanes.
COX-1 vs. COX-2
COX-1 vs. COX-2
COX-1 maintains normal physiological functions; COX-2 primarily mediates inflammation.
What are NSAIDs used for?
What are NSAIDs used for?
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Example of a Salicylate?
Example of a Salicylate?
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Examples of Propionic acid derivatives?
Examples of Propionic acid derivatives?
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Examples of Acetic acid derivatives?
Examples of Acetic acid derivatives?
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Examples of Enolic acid derivatives?
Examples of Enolic acid derivatives?
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Examples of Selective COX-2 inhibitors (coxibs)?
Examples of Selective COX-2 inhibitors (coxibs)?
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Common NSAID side effects?
Common NSAID side effects?
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Contraindications for NSAID?
Contraindications for NSAID?
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NSAID drug interactions?
NSAID drug interactions?
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Describe Aspirin function
Describe Aspirin function
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What should you monitor?
What should you monitor?
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Important to tell patients?
Important to tell patients?
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Study Notes
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Description
NSAIDs are a class of medications used for pain relief, fever reduction, and anti-inflammatory purposes. They inhibit cyclooxygenase (COX) enzymes, reducing prostaglandins and thromboxanes. They are effective for various conditions, but their use requires consideration of potential side effects.
