Podcast
Questions and Answers
Which leukocyte disorder is characterized by the failure of neutrophils to segment with coarseness of chromatin?
Which leukocyte disorder is characterized by the failure of neutrophils to segment with coarseness of chromatin?
- Chediak-Higashi syndrome
- Alder-Reilly anomaly
- May-Hegglin anomaly (correct)
- Pseudo-Pelger-Huët anomaly
In which disorder do neutrophils have long thin filaments and the entire cell is greatly enlarged and filled with nuclear material?
In which disorder do neutrophils have long thin filaments and the entire cell is greatly enlarged and filled with nuclear material?
- Pelger-Huët anomaly (correct)
- Neutrophil hypersegmentation
- Chediak-Higashi syndrome
- Pseudo-Pelger-Huët anomaly
Which leukocyte disorder is characterized by the presence of hyposegmented neutrophils with coarseness of chromatin and is inherited as an autosomal dominant trait?
Which leukocyte disorder is characterized by the presence of hyposegmented neutrophils with coarseness of chromatin and is inherited as an autosomal dominant trait?
- May-Hegglin anomaly (correct)
- Alder-Reilly anomaly
- Chediak-Higashi syndrome
- Neutrophil hypersegmentation
Which type of leukocyte disorder is characterized by the failure of neutrophils to segment and sometimes affects other white blood cells?
Which type of leukocyte disorder is characterized by the failure of neutrophils to segment and sometimes affects other white blood cells?
Which leukocyte disorder is characterized by the presence of 5 lobe neutrophils with the entire cell greatly enlarged and filled with nuclear material?
Which leukocyte disorder is characterized by the presence of 5 lobe neutrophils with the entire cell greatly enlarged and filled with nuclear material?
Flashcards
May-Hegglin anomaly
May-Hegglin anomaly
A leukocyte disorder where neutrophils fail to segment and have coarseness of chromatin.
Pelger-Huët anomaly
Pelger-Huët anomaly
A disorder characterized by neutrophils with long thin filaments, greatly enlarged cells filled with nuclear material.
Pseudo-Pelger-Huët anomaly
Pseudo-Pelger-Huët anomaly
A leukocyte disorder similar to Pelger-Huët but affects multiple white blood cells and lacks segmentation.
Hyposegmented neutrophils
Hyposegmented neutrophils
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Inheritance patterns in leukocyte disorders
Inheritance patterns in leukocyte disorders
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Study Notes
Neutrophil Disorders
- Pelger-Hüet Anomaly: Characterized by the failure of neutrophils to segment, presenting with coarseness in chromatin.
- Giant Neutrophil Syndrome: Neutrophils exhibit long thin filaments, with the entire cell significantly enlarged and filled with nuclear material.
- Hyposegmented Neutrophils with Coarseness of Chromatin: This disorder is characterized by hyposegmented neutrophils and is inherited as an autosomal dominant trait.
- Myelokathexis: A type of leukocyte disorder marked by the failure of neutrophils to segment, which may also affect other white blood cells.
- Hypersegmented Neutrophils: The presence of neutrophils with five lobes and greatly enlarged cells filled with nuclear material is a notable characteristic of this disorder.
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