Podcast
Questions and Answers
Which of the following is true about Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)?
Which of the following is true about Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)?
- They have a low protein binding capacity
- They are contained only in prescription combination drugs
- They are among the top 25 substances associated with the largest number of fatalities (correct)
- They are not commonly used and prescribed medications
What is the estimated prescription rate for NSAIDs in patients with rheumatologic diseases?
What is the estimated prescription rate for NSAIDs in patients with rheumatologic diseases?
- One in four
- One in three
- One in ten
- One in seven (correct)
Which statement is true regarding the distribution of most NSAIDs in the body?
Which statement is true regarding the distribution of most NSAIDs in the body?
- They obtain synovial fluid concentrations equal to or less than their plasma concentration
- They achieve synovial fluid concentrations equal to or greater than their plasma concentrations (correct)
- They have a small volume of distribution
- They do not penetrate inflamed joints
What is the typical bioavailability of most NSAIDs?
What is the typical bioavailability of most NSAIDs?
What percentage of protein binding do most NSAIDs have?
What percentage of protein binding do most NSAIDs have?
Which type of drugs are Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) considered to be?
Which type of drugs are Nonsteroidal Anti-Inflammatory Drugs (NSAIDs) considered to be?
Which is the most common adverse effect of NSAID use?
Which is the most common adverse effect of NSAID use?
Which NSAID shows a trend toward minimal cardiovascular risk?
Which NSAID shows a trend toward minimal cardiovascular risk?
What is the plasma elimination half-life range for piroxicam during therapeutic dosing?
What is the plasma elimination half-life range for piroxicam during therapeutic dosing?
Which NSAID undergoes extensive first-pass metabolism with an oral bioavailability of about 50%?
Which NSAID undergoes extensive first-pass metabolism with an oral bioavailability of about 50%?
What is the main route of excretion for most NSAIDs?
What is the main route of excretion for most NSAIDs?
Which NSAID is excreted 10% to 20% unchanged in the urine?
Which NSAID is excreted 10% to 20% unchanged in the urine?
What happens when the plasma protein binding of naproxen becomes saturated?
What happens when the plasma protein binding of naproxen becomes saturated?
What is the effect of overdoses of oral ibuprofen on its elimination half-life?
What is the effect of overdoses of oral ibuprofen on its elimination half-life?
What are the rare moderate and severe findings in NSAID overdose?
What are the rare moderate and severe findings in NSAID overdose?
What is the initial manifestation of symptoms after ingesting nonselective NSAIDs?
What is the initial manifestation of symptoms after ingesting nonselective NSAIDs?
Flashcards are hidden until you start studying
