Non-Selective Adrenergic Antagonists

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Questions and Answers

Which of the following is a non-selective adrenergic antagonist?

  • Labetalol (correct)
  • Amlodipine
  • Atorvastatin
  • Lisinopril

Non-selective adrenergic antagonists work by blocking the effects of which neurotransmitter?

  • Acetylcholine
  • Serotonin
  • Dopamine
  • Norepinephrine (correct)

What is a common effect of non-selective adrenergic antagonists on blood pressure?

  • No change in blood pressure
  • Increased blood pressure
  • Fluctuating blood pressure
  • Lower blood pressure (correct)

Which condition is commonly treated using non-selective adrenergic antagonists?

<p>Hypertension (B)</p> Signup and view all the answers

A patient with which pre-existing condition should use non-selective adrenergic antagonists with caution?

<p>Asthma (A)</p> Signup and view all the answers

What is a common adverse effect associated with non-selective adrenergic antagonists?

<p>Bradycardia (D)</p> Signup and view all the answers

Which of the following describes levels of renin when a patient is taking non-selective adrenergic antagonists?

<p>Decreased renin levels (A)</p> Signup and view all the answers

What effect do volatile liquid general anesthetics have when taken with non-selective adrenergic antagonists?

<p>Increased risk of hypotension (A)</p> Signup and view all the answers

Non-selective adrenergic antagonists may cause which of the following adverse effects?

<p>Blurry vision (B)</p> Signup and view all the answers

Besides hypertension, what is another condition treated by non-selective adrenergic antagonists?

<p>Arrhythmias (A)</p> Signup and view all the answers

Flashcards

Non-selective Adrenergic Antagonists: Action

Competitively block norepinephrine at alpha- and beta-receptors throughout the SNS.

Non-selective Adrenergic Antagonists: Effects

Lower blood pressure, slower pulse, increased renal perfusion, decreased renin levels.

Non-selective Adrenergic Antagonists: Treats

Hypertension, heart failure, arrhythmias.

Examples of Non-selective Adrenergic Antagonists

Amiodarone, carvedilol, labetalol.

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Non-selective Adrenergic Antagonists: Adverse Effects

Dizziness, bradycardia, hypotension, dyspnea, N/V, blurry vision, fatigue.

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Non-selective Adrenergic Antagonists: Cautions

Avoid in bradycardia, heart blocks, shock, heart failure, diabetes, bronchospasm, or asthma.

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Non-selective Adrenergic Antagonists: Drug Interactions

Volatile liquid general anesthetics, some diabetic agents, verapamil/diltiazem, QT prolonging medications.

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Study Notes

  • Non-selective adrenergic antagonists competitively block norepinephrine effects at alpha- and beta-receptors in the SNS.
  • Medications include amiodarone, carvedilol, and labetalol.
  • These antagonists lower blood pressure, slow pulse, increase renal perfusion, and decrease renin levels.
  • They treat hypertension, heart failure, and arrhythmias.
  • Contraindications include bradycardia, heart blocks, shock, heart failure, diabetes, bronchospasm, and asthma.
  • Adverse effects include dizziness, bradycardia, hypotension, dyspnea, N/V, blurry vision, and fatigue.
  • Drug interactions occur with volatile anesthetics, some diabetic agents, verapamil or diltiazem, and QT prolonging medications.

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