Non-pharmacologic Management of Ovarian Tumors and Ovarian Cancer
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Questions and Answers

What is a fibroadenoma?

  • A malignant breast lesion
  • A breast disorder with nipple discharge
  • A benign breast lesion with fibrotic stroma and glandular tissue (correct)
  • A type of ovarian tumor

How are complex fibroadenomas different from simple ones?

  • Simple fibroadenomas are bigger in size
  • Complex fibroadenomas show histologic characteristics like cysts and calcifications (correct)
  • Simple fibroadenomas are associated with nipple discharge
  • Complex fibroadenomas have unknown etiology

Which characteristic is typical of giant fibroadenomas?

  • Association with ovarian cancer
  • Fast-growing mass with poorly defined borders
  • Presence of nipple discharge
  • Size greater than five centimeters (correct)

What diagnostic procedures might be necessary for assessing a suspected fibroadenoma?

<p>Mammography and MRI (C)</p> Signup and view all the answers

What is the likely cause of fibroadenomas according to the text?

<p>Exaggerated response to normal hormonal stimuli (C)</p> Signup and view all the answers

Which characteristic does not apply to fibroadenomas?

<p>Usually associated with nipple discharge (C)</p> Signup and view all the answers

What are common symptoms associated with multiple papillomas in the breast?

<p>Clusters of masses in smaller ducts away from the nipple (A)</p> Signup and view all the answers

What type of nipple discharge is commonly associated with papillomas?

<p>Red, rusty, brown, greenish discharge (B)</p> Signup and view all the answers

What diagnostic tests are recommended for evaluating breast conditions?

<p>Prolactin level and mammogram (B)</p> Signup and view all the answers

Which group of medications may cause bilateral nipple discharge?

<p>Antihypertensives and antidepressants (B)</p> Signup and view all the answers

What is a common characteristic of breast cancer screening guidelines among various organizations?

<p>Varied recommendations based on personal history (B)</p> Signup and view all the answers

Which type of breast cancer is described as malignant neoplasm of glandular or stroma cells native to the breast?

<p>Ductal carcinoma in situ (D)</p> Signup and view all the answers

What role do BRCA1 and BRCA2 genes play in breast cancer?

<p>Act as tumor suppressor genes with mutation leading to cell cycle progression (B)</p> Signup and view all the answers

What percentage of tumors may interact with estrogen receptors and epidermal growth factor receptors?

<p>~33% (B)</p> Signup and view all the answers

What is one of the common benign conditions related to breast trauma?

<p>Cellulitis leading to abscess formation (A)</p> Signup and view all the answers

Which diagnostic imaging technique is recommended for breast assessment following nipple discharge presentation?

<p>Ultrasound examination (A)</p> Signup and view all the answers

What is the most common subtype of ovarian cancer?

<p>Epithelial ovarian cancer (D)</p> Signup and view all the answers

What is the leading cause of gynecologic related deaths in women?

<p>Ovarian cancer (A)</p> Signup and view all the answers

Which genetic syndrome increases the risk for colorectal, endometrial, stomach, small bowel, breast, pancreas, and ovarian cancers?

<p>Lynch syndrome (A)</p> Signup and view all the answers

What is the most significant risk factor for ovarian cancer?

<p>Multiple relatives with breast or ovarian cancer (D)</p> Signup and view all the answers

Which preventive measure has a protective effect against ovarian cancer but is considered controversial?

<p>Aspirin and NSAIDs use (A)</p> Signup and view all the answers

When should high-risk patients undergo pelvic examinations and CA-125 level measurements?

<p>Every six to 12 months (B)</p> Signup and view all the answers

What is advised for mutation carriers after childbearing is completed by the age of 35?

<p>Prophylactic oophorectomy (D)</p> Signup and view all the answers

What is a possible risk factor for ovarian cancer according to some studies?

<p>$BMI &gt; 30$ (B)</p> Signup and view all the answers

What is the recommendation of the US Preventative Services Task Force regarding alcohol use for patients at risk for breast cancer?

<p>Limit alcohol use, as even moderate intake increases risk (A)</p> Signup and view all the answers

Which medication is NOT recommended by the US Preventative Services Task Force for reducing the risk of breast cancer?

<p>Chemotherapy (B)</p> Signup and view all the answers

What is the American Cancer Society's stance on monthly breast self-exams?

<p>No longer recommends monthly self-exams (B)</p> Signup and view all the answers

At what age does the US Preventative Services Task Force recommend biennial mammograms?

<p>50 to 74 (A)</p> Signup and view all the answers

Which symptom may be a sign of advanced breast cancer?

<p>Swelling and redness of the skin (C)</p> Signup and view all the answers

How should a patient be positioned for visualizing skin dimpling during a breast examination?

<p>Supine (D)</p> Signup and view all the answers

What is the recommended daily dosage of tamoxifen for hormonal therapy?

<p>$20$ milligrams twice daily (C)</p> Signup and view all the answers

'Peau d'orange' refers to a characteristic appearance associated with what condition?

<p>Advanced breast cancer (C)</p> Signup and view all the answers

What is an indication for genetic testing in breast cancer based on the text?

<p>Having a family member diagnosed with breast cancer at any age (A)</p> Signup and view all the answers

Which of the following is NOT listed as a risk factor for breast cancer in the text?

<p>Having a family member with a BRCA mutation (C)</p> Signup and view all the answers

What would indicate the need for genetic testing in a patient with breast cancer according to the text?

<p>Having triple negative ER or PR or HER2 (D)</p> Signup and view all the answers

Which group of individuals is suggested to have an annual MRI beginning at age 30?

<p>Individuals with a relative risk of 2.1 to 4.0 for breast cancer (C)</p> Signup and view all the answers

What is indicated by having a family member diagnosed with aggressive prostate cancer with a Gleason score greater than seven?

<p>Indication for genetic testing (A)</p> Signup and view all the answers

Which condition would NOT typically lead to the recommendation of genetic testing according to the text?

<p>Alcohol use (C)</p> Signup and view all the answers

What is suggested as a risk factor for breast cancer in patients with a relative risk of 1.1 to 2.0?

<p>$2^{nd}$ degree relatives diagnosed at an early age (B)</p> Signup and view all the answers

What is the primary recommendation regarding screening for ovarian cancer in the general population?

<p>Routine use of CA-125 and transvaginal ultrasound for screening is not advised (D)</p> Signup and view all the answers

What is a common challenge associated with the CA-125 tumor marker in ovarian cancer diagnosis?

<p>It can be elevated in benign conditions, leading to false positives (B)</p> Signup and view all the answers

What is the recommended management approach for breast lesions less than three centimeters?

<p>Observe, do yearly imaging, and reassure the patient (A)</p> Signup and view all the answers

Which tumor markers are recommended for epithelial ovarian tumors?

<p>CA-125, CA-19-9, and CEA (C)</p> Signup and view all the answers

Which of the following is NOT a component of fibrocystic breast disease?

<p>Keratin cysts (B)</p> Signup and view all the answers

What physical examination finding is characteristic in patients with confirmed or suspected ovarian cancer?

<p>Abdominal mass (B)</p> Signup and view all the answers

What is the most common age group affected by intraductal papilloma?

<p>35-50 years (C)</p> Signup and view all the answers

Which imaging study is recommended for evaluating suspected ovarian cancer in high-risk individuals with a family history of the disease?

<p>CT scan with contrast of the abdomen and pelvis (C)</p> Signup and view all the answers

What is the role of CA 19-9 and CEA tumor markers in mucinous ovarian tumors?

<p>They are better indicators of disease compared to CA-125 (D)</p> Signup and view all the answers

What is the initial recommended dose of spironolactone for fibrocystic breast disease?

<p>100 milligrams daily (B)</p> Signup and view all the answers

What symptom differentiates the acute presentation of ovarian cancer from other conditions?

<p>Calf pain (B)</p> Signup and view all the answers

What increases the lifetime risk of breast cancer in women with intraductal papilloma?

<p>Multiple papillomas (C)</p> Signup and view all the answers

What characteristic separates non-mucinous epithelial tumors from other ovarian cancers?

<p><strong>Elevated inhibin A/B levels</strong> on diagnostic testing (D)</p> Signup and view all the answers

What is the primary reason behind the development of ductal ectasia?

<p>Unknown etiology (C)</p> Signup and view all the answers

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