Nitroimidazoles Overview

A group of drugs containing a nitroimidazole ring, effective against anaerobic bacteria and protozoa, and also show some activity against helminths.

The most commonly used nitroimidazole drug, available in various forms for oral, intravenous, topical, and rectal administration.

Another nitroimidazole drug similar to metronidazole, but with a longer half-life, requiring less frequent dosing.

A nitroimidazole drug with oral and intravenous administration routes, known for its potent activity.

A nitroimidazole drug primarily for oral administration, commonly used for various infections.

A nitroimidazole drug available orally, known for its broad spectrum of activity.

The ability of a drug to inhibit the growth of or kill microorganisms.

Different bacterial groups that lack the ability to survive in the presence of oxygen.

A group of bacteria that can survive in the presence or absence of oxygen.

Single-celled eukaryotic organisms that are often invisible without a microscope, some of which cause infections.

Multicellular parasitic worms that can infect humans and animals.

A specific molecule produced by an organism that acts as a signaling molecule.

The process by which a drug is absorbed, distributed, metabolized, and eliminated from the body.

The study of how drugs interact with living organisms, focusing on their effects and mechanisms of action.

The specific way that a drug interacts with its target to produce its effects.

A drug that is inactive in its original form and must be metabolized in the body to become active.

The process by which a drug is broken down into smaller molecules in the body.

An unwanted or harmful effect that occurs during drug use.

A situation where two or more drugs interact within the body, potentially changing their effects.

A condition where an individual develops excessive sensitivity to a drug, leading to exaggerated or unexpected reactions.

The ability of a drug to pass through biological barriers, such as cell membranes, to reach its target site.

The concentration of a drug in the blood or other bodily fluids.

The length of time it takes for the concentration of a drug in the body to decrease by half.

The ability of a drug to pass through the barrier between the bloodstream and the central nervous system.

When a drug is administered directly into the bloodstream.

An area of the body that is inflamed or infected.

A condition involving inflammation of the gums, typically caused by various bacteria.

A condition affecting the brain where bacteria or other pathogens have invaded the brain tissue.

A condition characterized by an excessive growth of the Candida fungus, often causing oral thrush.

A severe complication of diarrhea caused by an overgrowth of Clostridium difficile bacteria.

A complex condition involving inflammation of the intestines, often associated with abdominal pain and changes in bowel habits.

An infection caused by the Helicobacter pylori bacteria, commonly residing in the stomach and duodenum.

A type of drug that works by inhibiting the synthesis of proteins within a cell.

A condition involving inflammation of the gums near a partially erupted tooth.