NIH Grant and Financial Interests
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An investigator received $4,000 in consulting income from a publicly traded drug company and owns $2,000 worth of stock in the same company. They are submitting an NIH grant to evaluate the company's drug. Which statement is true regarding significant financial interest?

  • The investigator does not have a significant financial interest because the stock's value is less than $5,000.
  • The value of stock is not calculated when determining significant financial interests.
  • The investigator does not have a significant financial interest because the consulting income is less than $5,000.
  • The aggregate of the consulting income and the stock exceeds $5,000 and therefore is a significant financial interest. (correct)

An investigator received $4,000 of consulting income from a publicly traded drug company and owns stock in that company valued at $2,000. They are submitting a grant to the National Institutes of Health to evaluate the company's drug. Which statement is true?

  • The investigator does not have a significant financial interest because the consulting income is less than $5,000.
  • The investigator does not have a significant financial interest because the stock's value is less than $5,000.
  • The aggregate of the consulting income and the stock exceeds $5,000 and therefore is a significant financial interest. (correct)
  • The value of stock is not calculated when determining significant financial interests.

When do investigators pursuing research have to disclose significant financial interests?

  • Prior to the submission of a grant proposal. (correct)
  • Only after the research is completed and results are published.
  • Only if the research involves human subjects.
  • Only if the research is funded by a non-profit organization.

What is the primary purpose of conflict of interest policies in research?

<p>To protect the integrity of research by ensuring objectivity. (D)</p> Signup and view all the answers

Which of the following would typically be considered a financial conflict of interest in research?

<p>Receiving royalties from a patented technology used in the research. (D)</p> Signup and view all the answers

What action should an investigator take if they identify a potential conflict of interest?

<p>Disclose the conflict to the relevant authorities and follow their guidance. (B)</p> Signup and view all the answers

Flashcards

Significant Financial Interest Threshold

Financial interests exceeding $5,000 (including the value of equity and consulting income) in a publicly traded entity.

Evaluating Effectiveness

A comprehensive study to determine the effectiveness or lack thereof of a particular intervention or substance.

Consulting Income

Income received for providing expertise or services to a company.

Stock Ownership

Ownership stake in a company,represented by shares of stock.

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Conflict of Interest Disclosure

Obligation to disclose significant financial relationships that could bias research.

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What constitutes a 'financial interest'?

Anything of monetary value, including salary, consulting fees, equity interests (e.g., stocks), and intellectual property rights (e.g., patents, copyrights)

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What is a 'significant financial interest'?

A financial interest consisting of one or more of the following: (1) >$5,000 in payments/equity in a publicly traded entity, or (2) >$0 payments/equity in a non-publicly traded entity.

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How are consulting income and stock value treated?

Consulting income and stock value are combined when assessing significant financial interests.

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When does consulting income PLUS stock constitute a significant financial interest?

An investigator has a significant financial interest if the aggregate of their consulting income and stock value in a publicly traded company exceeds $5,000 and the research they are undertaking could affect the value of the company.

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