Neurotransmitters by Dr. Mukhtiar Baig
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Questions and Answers

What is the primary function of neurotransmitters in the nervous system?

  • To relay, amplify, and modulate electrical signals between a neuron and another cell (correct)
  • To produce electrical signals between neurons
  • To create a physical connection between neurons
  • To generate synaptic clefts

What is the term for the microscopic gap between neurons?

  • Axon-dendrite connection
  • Synaptic cleft (correct)
  • Neurotransmitter gap
  • Synapse

What is a common feature among neurotransmitters?

  • Ability to bind to postsynaptic receptors (correct)
  • Inability to bind to postsynaptic receptors
  • Presence of receptors in the presynaptic element
  • Presence of precursors and/or synthetic enzymes in the postsynaptic side

What type of neurotransmitter is dopamine?

<p>Monoamine (C)</p> Signup and view all the answers

What is the result of an excitatory postsynaptic potential (EPSP) on the postsynaptic membrane?

<p>Depolarization (C)</p> Signup and view all the answers

What is the final step in the processing of neurotransmitters?

<p>Inactivation (C)</p> Signup and view all the answers

What is the result of the binding of glycine to its receptor?

<p>Hyperpolarization of the post-synaptic membrane (A)</p> Signup and view all the answers

What is the function of the enzyme histaminase in the formation of histamine?

<p>Catalyzing the decarboxylation of histidine (A)</p> Signup and view all the answers

What is the effect of glutamate on the post-synaptic membrane?

<p>It causes depolarization (A)</p> Signup and view all the answers

What is the fate of glutamate in astrocytes?

<p>It is converted to glutamine (D)</p> Signup and view all the answers

What is the importance of the conversion of glutamate to glutamine?

<p>It removes ammonia from the brain (C)</p> Signup and view all the answers

What is the effect of increased levels of glutamate in the brain?

<p>It causes death to the neurons in the brain (D)</p> Signup and view all the answers

What is the effect of low levels of glutamine in the brain?

<p>Tiredness and poor brain activity (A)</p> Signup and view all the answers

Which of the following is NOT a function of GABA?

<p>Increasing the levels of glutamate in the brain (B)</p> Signup and view all the answers

What is the coenzyme required for the formation of GABA?

<p>Vitamin B6 (B)</p> Signup and view all the answers

Serotonin is primarily produced in the:

<p>Intestine (C)</p> Signup and view all the answers

What is the relationship between serotonin and depression?

<p>Depressed patients have lower levels of serotonin (B)</p> Signup and view all the answers

Which of the following is a function of serotonin?

<p>Regulating muscle contraction (A)</p> Signup and view all the answers

What is the primary neurotransmitter produced by the adrenal medulla?

<p>Norepinephrine (D)</p> Signup and view all the answers

What is the principal metabolite of serotonin in urine?

<p>5-Hydroxyindoleacetic acid (B)</p> Signup and view all the answers

What is the first enzyme in the pathway of serotonin metabolism?

<p>Tryptophan hydroxylase (A)</p> Signup and view all the answers

What is the precursor amino acid for serotonin synthesis?

<p>Tryptophan (A)</p> Signup and view all the answers

Where is serotonin present in the highest concentration?

<p>Blood platelets (D)</p> Signup and view all the answers

What is the enzyme responsible for the synthesis of dopamine, norepinephrine, and epinephrine?

<p>Tyrosine hydroxylase (B)</p> Signup and view all the answers

What is the result of low levels of norepinephrine?

<p>Lack of energy (C)</p> Signup and view all the answers

What is the function of epinephrine in the brain?

<p>Regulation of attention and mental focus (B)</p> Signup and view all the answers

What is the link between dopamine and Parkinson's disease?

<p>Decreased dopamine levels cause Parkinson's disease (D)</p> Signup and view all the answers

What is the enzyme responsible for the synthesis of acetylcholine?

<p>Choline acetyltransferase (D)</p> Signup and view all the answers

What is the function of acetylcholine in the peripheral nervous system?

<p>Causes skeletal muscles to contract (B)</p> Signup and view all the answers

What is the result of increased dopamine levels in the brain?

<p>Schizophrenia (A)</p> Signup and view all the answers

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