🎧 New: AI-Generated Podcasts Turn your study notes into engaging audio conversations. Learn more

Neurotransmitters and Catecholamines Quiz
10 Questions
1 Views

Neurotransmitters and Catecholamines Quiz

Created by
@CreativeLithium

Podcast Beta

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What is the rate-limiting enzyme in catecholamine biosynthesis?

Tyrosine hydroxylase (TH, tyrosine 3-monooxygenase)

What are the cofactors required by tyrosine hydroxylase for catecholamine biosynthesis?

Tetrahydrobiopterin (BH4) and ferrous iron (Fe2+)

What is the primary function of dopamine in the brain?

Dopamine functions independently as a neurotransmitter.

What are the structural components of tyrosine hydroxylase?

<p>Regulatory domain containing phosphorylation sites and catalytic domain</p> Signup and view all the answers

What is the long-term, nearly irreversible type of end product inhibition of tyrosine hydroxylase?

<p>Binding of catechols to the Fe3+ ion at the catalytic site</p> Signup and view all the answers

What is the alternate pathway for the formation of tyrosine in patients diagnosed with phenylketonuria?

<p>Hydroxylation of phenylalanine to form tyrosine</p> Signup and view all the answers

What enzyme catalyzes the conversion of L-DOPA to dopamine?

<p>Aromatic amino acid decarboxylase (AAAD) or DOPA decarboxylase</p> Signup and view all the answers

How is dopamine metabolized within the terminal?

<p>By monoamine oxidase (MAO) specifically by MAO-A and in some areas by catechol-O-methyl transferase (COMT)</p> Signup and view all the answers

What is the principal metabolite of dopamine resulting from MAO and aldehyde dehydrogenase activity?

<p>3,4-dihydroxyphenylacetic acid (DOPAC)</p> Signup and view all the answers

How are the physiological actions of catecholamines terminated?

<p>By reuptake into the neuron, catabolism, and diffusion</p> Signup and view all the answers

More Quizzes Like This

Use Quizgecko on...
Browser
Browser