Neurotransmitter Receptor Quiz
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Questions and Answers

A neurotransmitter receptor is a membrane receptor protein that is activated by a ______.

neurotransmitter

If a neurotransmitter bumps into its corresponding receptor, they will ______ and can trigger other events to occur inside the cell.

bind

The influx of ions through ion channels opened due to the binding of neurotransmitters to specific receptors can change the ______ potential of a neuron.

membrane

AMPA is a specific agonist for the ______ receptor, where it mimics the effects of the neurotransmitter glutamate.

<p>AMPA</p> Signup and view all the answers

AMPA generates fast excitatory ______ potentials (EPSP).

<p>postsynaptic</p> Signup and view all the answers

AMPA activates AMPA receptors that are non-selective cationic channels allowing the passage of Na+ and K+ and therefore have an equilibrium potential near ______ mV.

<p>0</p> Signup and view all the answers

The NMDA receptor is one of three types of ______ receptors

<p>ionotropic</p> Signup and view all the answers

The ligands for the NMDA receptor are ______ and glycine (or D-serine)

<p>glutamate</p> Signup and view all the answers

The NMDA receptor acts as a 'coincidence detector' and only opens when both glutamate and glycine (or D-serine) are present and the neuron is sufficiently [blanked]

<p>depolarized</p> Signup and view all the answers

γ-Aminobutyric acid (GABA) is the chief ______ neurotransmitter in the developmentally mature mammalian central nervous system.

<p>inhibitory</p> Signup and view all the answers

GABAB receptors are ______ receptors, which are G protein-coupled receptors that open or close ion channels via intermediaries (G proteins)

<p>metabotropic</p> Signup and view all the answers

Neurons that produce GABA as their output are called GABAergic neurons, and have chiefly ______ action at receptors in the adult vertebra.

<p>inhibitory</p> Signup and view all the answers

Study Notes

Neurotransmitter Receptors

  • Membrane receptor proteins activated by neurotransmitters.
  • Interaction with corresponding receptors can trigger intracellular events.
  • Influx of ions through opened ion channels alters the membrane potential of neurons.

AMPA Receptor

  • AMPA is an agonist for the glutamate receptor, mimicking glutamate's effects.
  • Generates fast excitatory postsynaptic potentials (EPSP).
  • Activates non-selective cationic channels, allowing Na+ and K+ passage.
  • Equilibrium potential of AMPA receptors is approximately +60 mV.

NMDA Receptor

  • One of three key types of glutamate receptors.
  • Ligands include glutamate and glycine (or D-serine).
  • Functions as a 'coincidence detector': only opens in the presence of both glutamate and glycine (or D-serine) while the neuron is adequately depolarized.

GABA and GABAB Receptors

  • γ-Aminobutyric acid (GABA) serves as the primary inhibitory neurotransmitter in mature mammalian CNS.
  • GABAB receptors are G protein-coupled receptors that modulate ion channels through G proteins.
  • Neurons that release GABA are referred to as GABAergic neurons, primarily exerting inhibitory actions in adult vertebrates.

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Description

Test your knowledge of neurotransmitter receptors and their functions with this quiz. Learn about the different types of receptors and how they interact with neurotransmitters to produce various physiological effects. Keywords: neurotransmitter, receptor protein, membrane receptor, binding, physiological effects.

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