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Neurotransmission at Neuromuscular Junction

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Neurotransmission at Neuromuscular Junction

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Questions and Answers

What is the characteristic of the conduction of signals in muscle cells?

Signal dies out after a certain distance (correct)
graded potential
Saltatory conduction
Signal propagation without decrement

What is the effect of low calcium and high magnesium/curare on vesicle release?

Vesicle release becomes more synchronized
Reduced vesicle release (correct)
No effect on vesicle release
Increased vesicle release

What is the amplitude of miniature end plate potentials (MEPPs)?

1 mV
10 mV
0.5 mV (correct)
5 mV

What causes the spontaneous release of vesicles in the neuromuscular junction?

ACh vesicles colliding spontaneously with the nerve terminal (A) Signup and view all the answers

What is the distribution of MEPPs observed by Katz?

Poisson distribution (B) Signup and view all the answers

What is the mechanism of the knee jerk reflex?

Mechanical stretching of a tendon (B) Signup and view all the answers

What is the effect of curare on vesicle release?

Decreases vesicle release (C) Signup and view all the answers

What is the term for the small depolarizations of the postsynaptic terminal caused by the release of a single vesicle?

Miniature end plate potential (A) Signup and view all the answers

What is the significance of the observation of spontaneous MEPPs?

It implies that MEPPs can occur spontaneously due to random release of vesicles (D) Signup and view all the answers

What is the site of the mechanical stretching that causes the knee jerk reflex?

Tendon (C) Signup and view all the answers