Neurotransmission at Neuromuscular Junction

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Questions and Answers

What is the characteristic of the conduction of signals in muscle cells?

  • Signal dies out after a certain distance (correct)
  • graded potential
  • Saltatory conduction
  • Signal propagation without decrement

What is the effect of low calcium and high magnesium/curare on vesicle release?

  • Vesicle release becomes more synchronized
  • Reduced vesicle release (correct)
  • No effect on vesicle release
  • Increased vesicle release

What is the amplitude of miniature end plate potentials (MEPPs)?

  • 1 mV
  • 10 mV
  • 0.5 mV (correct)
  • 5 mV

What causes the spontaneous release of vesicles in the neuromuscular junction?

<p>ACh vesicles colliding spontaneously with the nerve terminal (A)</p> Signup and view all the answers

What is the distribution of MEPPs observed by Katz?

<p>Poisson distribution (B)</p> Signup and view all the answers

What is the mechanism of the knee jerk reflex?

<p>Mechanical stretching of a tendon (B)</p> Signup and view all the answers

What is the effect of curare on vesicle release?

<p>Decreases vesicle release (C)</p> Signup and view all the answers

What is the term for the small depolarizations of the postsynaptic terminal caused by the release of a single vesicle?

<p>Miniature end plate potential (A)</p> Signup and view all the answers

What is the significance of the observation of spontaneous MEPPs?

<p>It implies that MEPPs can occur spontaneously due to random release of vesicles (D)</p> Signup and view all the answers

What is the site of the mechanical stretching that causes the knee jerk reflex?

<p>Tendon (C)</p> Signup and view all the answers

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