Neurotransmission and Acetylcholine
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Questions and Answers

What is the effect of acetylcholine on the postsynaptic cell membrane?

  • It decreases the permeability of the membrane to Na+
  • It has no effect on the permeability of the membrane to any ions
  • It increases the permeability of the membrane to K+
  • It increases the permeability of the membrane to Na+ (correct)

    • What is the role of choline acetyltransferase in acetylcholine synthesis?

  • It catalyzes the reaction between active acetate and choline (correct)
  • It converts Na+ into K+ in the postsynaptic cell membrane
  • It activates the uptake of acetate into cholinergic neurons
  • It breaks down acetylcholine into choline and acetate

    • Where is acetylcholinesterase primarily found in the body?

  • In the synapse
  • In the plasma
  • In the cell membranes at nerve terminals that are cholinergic (correct)
  • In the cytoplasm of cholinergic nerve endings

    • What is the purpose of acetylcholinesterase in the synapse?

    <p>To rapidly remove acetylcholine from the synapse</p> Signup and view all the answers

    What is the result of acetylcholine binding to receptors on the postsynaptic cell membrane?

    <p>The postsynaptic cell becomes depolarized or excited</p> Signup and view all the answers

    What is the role of choline in acetylcholine synthesis?

    <p>It reacts with acetate to form acetylcholine</p> Signup and view all the answers

    What is required for a neuron to be stimulated?

    <p>A sufficient amount of transmitter substance</p> Signup and view all the answers

    What is the process by which acetylcholine is released into the synaptic cleft?

    <p>Exocytosis</p> Signup and view all the answers

    What is necessary for a substance to be considered a neurotransmitter?

    <p>It must be synthesized in the body of the neuron</p> Signup and view all the answers

    What is the primary function of Ca2+ ions in the synaptic terminal?

    <p>To allow synaptic vesicles to move to and bind with the presynaptic membrane</p> Signup and view all the answers

    What is the effect of an impulse arriving at a synaptic knob on the membrane?

    <p>Increased Ca2+ permeability</p> Signup and view all the answers

    What is the purpose of acetylcholinesterase (AChE) in the synaptic cleft?

    <p>To break down ACh into acetyl and choline</p> Signup and view all the answers

    What is the result of ACh binding to ACh receptors at the motor end plate?

    <p>Depolarization of the muscle cell</p> Signup and view all the answers

    What is the function of neurotransmitters in the nervous system?

    <p>To transmit signals between neurons</p> Signup and view all the answers

    What is the classification of Glutamate, Glycine, and GABA based on their chemical structure?

    <p>Amino Acids</p> Signup and view all the answers

    What is the outcome of the action potential spreading along the sarcolemma and down the T-tubules?

    <p>Triggering of the sarcoplasmic reticulum to release Ca2+</p> Signup and view all the answers

    What happens when an action potential travels down the motor neuron's axon?

    <p>Altered permeability of the synaptic terminal membrane and an influx of calcium</p> Signup and view all the answers

    What is the result of the depolarization at the motor end plate?

    <p>The muscle cell becomes more responsive to stimuli</p> Signup and view all the answers

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