Neurotransmission and Acetylcholine

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What is the effect of acetylcholine on the postsynaptic cell membrane?

It decreases the permeability of the membrane to Na+
It has no effect on the permeability of the membrane to any ions
It increases the permeability of the membrane to K+
It increases the permeability of the membrane to Na+ (correct)

What is the role of choline acetyltransferase in acetylcholine synthesis?

It catalyzes the reaction between active acetate and choline (correct)
It converts Na+ into K+ in the postsynaptic cell membrane
It activates the uptake of acetate into cholinergic neurons
It breaks down acetylcholine into choline and acetate

Where is acetylcholinesterase primarily found in the body?

In the synapse
In the plasma
In the cell membranes at nerve terminals that are cholinergic (correct)
In the cytoplasm of cholinergic nerve endings

What is the purpose of acetylcholinesterase in the synapse?

To rapidly remove acetylcholine from the synapse (B) Signup and view all the answers

What is the result of acetylcholine binding to receptors on the postsynaptic cell membrane?

The postsynaptic cell becomes depolarized or excited (B) Signup and view all the answers

What is the role of choline in acetylcholine synthesis?

It reacts with acetate to form acetylcholine (D) Signup and view all the answers

What is required for a neuron to be stimulated?

A sufficient amount of transmitter substance (A) Signup and view all the answers

What is the process by which acetylcholine is released into the synaptic cleft?

Exocytosis (C) Signup and view all the answers

What is necessary for a substance to be considered a neurotransmitter?

It must be synthesized in the body of the neuron (A) Signup and view all the answers

What is the primary function of Ca2+ ions in the synaptic terminal?

To allow synaptic vesicles to move to and bind with the presynaptic membrane (A) Signup and view all the answers

What is the effect of an impulse arriving at a synaptic knob on the membrane?

Increased Ca2+ permeability (A) Signup and view all the answers

What is the purpose of acetylcholinesterase (AChE) in the synaptic cleft?

To break down ACh into acetyl and choline (B) Signup and view all the answers

What is the result of ACh binding to ACh receptors at the motor end plate?

Depolarization of the muscle cell (A) Signup and view all the answers

What is the function of neurotransmitters in the nervous system?

To transmit signals between neurons (B) Signup and view all the answers

What is the classification of Glutamate, Glycine, and GABA based on their chemical structure?

Amino Acids (C) Signup and view all the answers

What is the outcome of the action potential spreading along the sarcolemma and down the T-tubules?

Triggering of the sarcoplasmic reticulum to release Ca2+ (C) Signup and view all the answers

What happens when an action potential travels down the motor neuron's axon?

Altered permeability of the synaptic terminal membrane and an influx of calcium (C) Signup and view all the answers

What is the result of the depolarization at the motor end plate?

The muscle cell becomes more responsive to stimuli (B) Signup and view all the answers