18 Questions
What is the effect of acetylcholine on the postsynaptic cell membrane?
It increases the permeability of the membrane to Na+
What is the role of choline acetyltransferase in acetylcholine synthesis?
It catalyzes the reaction between active acetate and choline
Where is acetylcholinesterase primarily found in the body?
In the cell membranes at nerve terminals that are cholinergic
What is the purpose of acetylcholinesterase in the synapse?
To rapidly remove acetylcholine from the synapse
What is the result of acetylcholine binding to receptors on the postsynaptic cell membrane?
The postsynaptic cell becomes depolarized or excited
What is the role of choline in acetylcholine synthesis?
It reacts with acetate to form acetylcholine
What is required for a neuron to be stimulated?
A sufficient amount of transmitter substance
What is the process by which acetylcholine is released into the synaptic cleft?
Exocytosis
What is necessary for a substance to be considered a neurotransmitter?
It must be synthesized in the body of the neuron
What is the primary function of Ca2+ ions in the synaptic terminal?
To allow synaptic vesicles to move to and bind with the presynaptic membrane
What is the effect of an impulse arriving at a synaptic knob on the membrane?
Increased Ca2+ permeability
What is the purpose of acetylcholinesterase (AChE) in the synaptic cleft?
To break down ACh into acetyl and choline
What is the result of ACh binding to ACh receptors at the motor end plate?
Depolarization of the muscle cell
What is the function of neurotransmitters in the nervous system?
To transmit signals between neurons
What is the classification of Glutamate, Glycine, and GABA based on their chemical structure?
Amino Acids
What is the outcome of the action potential spreading along the sarcolemma and down the T-tubules?
Triggering of the sarcoplasmic reticulum to release Ca2+
What happens when an action potential travels down the motor neuron's axon?
Altered permeability of the synaptic terminal membrane and an influx of calcium
What is the result of the depolarization at the motor end plate?
The muscle cell becomes more responsive to stimuli
Learn about the role of acetylcholine in neurotransmission, its synthesis, release, and degradation. Understand how it acts on receptors to increase membrane permeability, causing depolarization and excitation of neurons.
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