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Questions and Answers
What are the main structural differences between sensory and motor neurons?
What are the main structural differences between sensory and motor neurons?
Sensory neurons are pseudounipolar with their cell bodies outside the CNS, while motor neurons are multipolar with their cell bodies in the CNS.
Describe the pathway of sensory and motor neurons in relation to the spinal nerve.
Describe the pathway of sensory and motor neurons in relation to the spinal nerve.
Sensory neurons enter the spinal cord via the dorsal root and exit through the spinal nerve, while motor neurons exit the spinal cord through the ventral root.
How does the composition of gray matter differ from that of white matter in the spinal cord?
How does the composition of gray matter differ from that of white matter in the spinal cord?
Gray matter contains little myelin and consists of cell bodies and dendrites, while white matter is composed of myelinated axons and has a higher lipid content.
What roles do the dorsal and ventral horns play in the spinal cord's structure?
What roles do the dorsal and ventral horns play in the spinal cord's structure?
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Explain the relationship between the spinal cord, spinal nerves, and the meninges.
Explain the relationship between the spinal cord, spinal nerves, and the meninges.
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What are the primary actions of the trapezius muscle?
What are the primary actions of the trapezius muscle?
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Which nerves innervate the biceps brachii and brachialis muscles?
Which nerves innervate the biceps brachii and brachialis muscles?
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How does the innervation of the quadriceps femoris group contribute to its function?
How does the innervation of the quadriceps femoris group contribute to its function?
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What is the primary function of the latissimus dorsi muscle?
What is the primary function of the latissimus dorsi muscle?
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Describe the significance of the median nerve in the forearm muscles.
Describe the significance of the median nerve in the forearm muscles.
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Which muscle group is responsible for the dorsiflexion of the foot?
Which muscle group is responsible for the dorsiflexion of the foot?
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What is the function of the rotator cuff muscles?
What is the function of the rotator cuff muscles?
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Explain the role of deep fascia in muscle compartments.
Explain the role of deep fascia in muscle compartments.
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What actions do the gluteus maximus muscles facilitate?
What actions do the gluteus maximus muscles facilitate?
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Identify the nerve that innervates the hypothenar muscles of the hand.
Identify the nerve that innervates the hypothenar muscles of the hand.
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What is a muscle twitch and how does it relate to muscle contraction?
What is a muscle twitch and how does it relate to muscle contraction?
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Why are muscle responses considered graded?
Why are muscle responses considered graded?
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What role does motor unit recruitment play in muscle contraction strength?
What role does motor unit recruitment play in muscle contraction strength?
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Explain the concept of muscle tone and its physiological significance.
Explain the concept of muscle tone and its physiological significance.
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How does frequency of stimulation affect muscle contraction?
How does frequency of stimulation affect muscle contraction?
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Describe the difference between fast twitch and slow twitch muscle fibers.
Describe the difference between fast twitch and slow twitch muscle fibers.
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What happens during complete tetanus and its implications for muscle function?
What happens during complete tetanus and its implications for muscle function?
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What is the significance of threshold stimulation in muscle contraction?
What is the significance of threshold stimulation in muscle contraction?
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What role do muscle spindle receptors play in maintaining posture?
What role do muscle spindle receptors play in maintaining posture?
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How does the Golgi tendon organ contribute to muscle function?
How does the Golgi tendon organ contribute to muscle function?
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Explain the purpose of the crossed-extensor reflex in relation to the withdrawal reflex.
Explain the purpose of the crossed-extensor reflex in relation to the withdrawal reflex.
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What is the significance of paresthesia in the context of peripheral nerve injury?
What is the significance of paresthesia in the context of peripheral nerve injury?
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Differentiate between hyporeflexia and areflexia following a peripheral nerve injury.
Differentiate between hyporeflexia and areflexia following a peripheral nerve injury.
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What is the main difference between isometric and isotonic muscle contractions?
What is the main difference between isometric and isotonic muscle contractions?
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Describe the three metabolic pathways for ATP generation in muscles.
Describe the three metabolic pathways for ATP generation in muscles.
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What sequence of energy stores is utilized during the early phases of muscle activity?
What sequence of energy stores is utilized during the early phases of muscle activity?
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Compare slow oxidative fibers with fast glycolytic fibers in muscle types.
Compare slow oxidative fibers with fast glycolytic fibers in muscle types.
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What are the primary physiological changes in skeletal muscle due to resistance training?
What are the primary physiological changes in skeletal muscle due to resistance training?
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How does aging affect skeletal muscle and its recovery?
How does aging affect skeletal muscle and its recovery?
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Explain the concept of disuse atrophy in skeletal muscle.
Explain the concept of disuse atrophy in skeletal muscle.
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Identify other body systems that are influenced by regular exercise.
Identify other body systems that are influenced by regular exercise.
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What are the components of a reflex arc?
What are the components of a reflex arc?
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Differentiate between concentric and eccentric contractions.
Differentiate between concentric and eccentric contractions.
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Study Notes
Sensory and Motor neurons
- Sensory neurons: Pseudounipolar, cell body outside CNS, collect information from periphery and carry to CNS, afferent, no dendrites
- Motor neurons: Multipolar, cell body and dendrites located within CNS, convey information from CNS to periphery, efferent
Spinal Cord Anatomy
- Sensory neurons enter spinal cord through dorsal root
- Cell bodies of sensory neurons located within dorsal root ganglion
- Motor neurons leave spinal cord through ventral root
- Spinal nerve forms as dorsal and ventral roots come together, carrying both sensory and motor neurons
- Gray matter: Darker areas of brain, little myelin present, doesn't appear white
- White matter: White areas of brain, myelin present giving white color, myelinated axons in CNS
- Dorsal horn: Contains sensory neurons, dorsal half of spinal cord
- Ventral horn: Contains motor neurons, ventral half of spinal cord
Meninges and Vertebral Column
- Meninges are layers of membranous tissue protecting brain and spinal cord
- Meninges consist of pia, arachnoid mater/subarachnoid space and dura mater
- Spinal cord is innervated by sacral nerves
Shoulder Muscles
- Pectoral girdle: Consists of clavicle and scapula, traps help elevate or depress scapula, rhomboids retract scapula, serratus anterior helps with protraction and raising arm above head
- Humerus movement: Pectoralis major flexes, adducts and medially rotates arm, deltoids abduct, lat dorsi and teres major extend, adduct and medially rotate arm
- Rotator Cuff Muscles: Supraspinatus abducts arm, infraspinatus and teres minor laterally rotate arm, subscapularis medially rotates arm
Arm Muscles
- Biceps brachii and brachialis: Flexes and supinates forearm at elbow joint
- Triceps brachii: Extends forearm at elbow joint, returns it to anatomical position
Forearm and Hand Muscles
- Anterior forearm: Flexes wrist and fingers, innervated by median and ulnar nerves
- Posterior forearm: Extends wrist and fingers, innervated by radial nerve
- Anterior forearm muscles: Flexor carpi ulnaris, palmaris longus and flexor carpi radialis flex wrist
- Posterior forearm: Extension of wrist and fingers, radial nerve
- Muscles of the hand: Hypothenar moves pinky finger (ulnar nerve), thenar moves thumb (median nerve)
Hip and Thigh Muscles
- Anterior Hip: Innervated by femoral nerves, iliopsoas (iliacus and psoas major) flexes thigh at hip joint, rectus femoris extends knee, sartorius flexes hip and knee and laterally rotates thigh
- Posterior Hip: Gluteus maximus extends and laterally rotates thigh
- Anterior Thigh: Innervated by femoral nerve, quadriceps femoris extend leg at knee, rectus femoris extends leg and flexes hip, vastus lateralis and vastus medialis extend knee
- Medial Thigh: Adduction of hip, innervated by obturator nerve
- Posterior Thigh: Innervated by tibial nerve, hamstrings flex leg at knee joint, consists of biceps femoris, semitendinosus and semimembranosus
- Tensor fascia: Present on lateral thigh, acts with gluteus maximus, locks knee in extension
Leg Muscles
- Anterior Leg: Innervated by common fibular nerve, tibialis anterior dorsiflexes foot, extensor digitorum longus extends toes, extensor hallucis longus extends big toe
- Lateral leg: Innervated by common fibular nerve, fibularis longus everts foot and plantarflexes
- Posterior Leg: Innervated by tibial nerve, gastrocnemius and soleus help plantar flex, these tendons insert onto the calcaneal tendon
Nerve Supply to Limbs
- Upper Limb (brachial plexus): Axillary (shoulder), musculocutaneous (biceps brachii and brachialis), radial (posterior forearm), ulnar (ulnar side of anterior forearm and most of hand), median (muscles in thumb and anterior forearm)
- Lower Limb (lumbar/sacral plexuses): Femoral (anterior thigh), common fibular (lateral and anterior leg), tibial (posterior thigh), obturator (medial thigh)
Muscle Compartments in Limbs
- Deep fascia surrounds muscle compartments
- Fascia doesn't stretch leading to compression of nerves and blood vessels
- Compression can lead to pain and reduced blood flow
Motor Unit
- Motor unit is a single motor neuron and the muscle fibers it controls, all or nothing response
- Small motor units (eye muscles) provide more control
- Big motor units (lower limbs) provide less precise control
Muscle Twitch and Tension
- Myosin produces tension pulling on actin, causing sarcomere to shorten and muscle to contract
- Muscle twitch is response to single electrical stimulation
Graded Muscle Responses
- Different tasks require different muscle fibers and energy expenditure
- Frequency of stimulation: Influences muscle contraction strength, low frequency allows muscle relaxation, high frequency results in tetanus (no muscle relaxation)
- Strength of stimulation: Sub-threshold stimuli produces no muscle contraction, threshold stimuli produces first observable contraction, stronger stimulation recruits more motor units, increasing force of contraction
Muscle Tone
- Muscle tone is slight contraction of muscles, always present
- Muscle tone helps with posture, driven by involuntary muscle movement
- Muscle tone decreases with sleep
Isometric and Isotonic Contractions
- Isometric: Muscle stays same length while developing tension
- Isotonic: Muscle generates force and shortens while lifting a weight
- Concentric isotonic: Muscle shortens while doing work
- Eccentric isotonic: Muscle generates force while lengthening
Muscle Metabolic Pathways
- Direct Phosphorylation of ADP: Creatine phosphate provides phosphate needed to convert ADP to ATP, fastest ATP production, used for quick energy bursts
- Anaerobic Respiration (Glycolysis): Glucose from glycogen stores is converted to pyruvic acid, releases 2 ATP, short-term energy supply, lactic acid builds up
- Aerobic Respiration: Occurs in mitochondria, requires oxygen, produces 32 ATP per glucose molecule, long-term energy supply
Energy Stores in Muscle Activity
- ATP stored in muscles used first
- CP regenerates more ATP
- Glycogen stored in muscles broken down into glucose for ATP production
- Sustained activity relies on aerobic respiration
Muscle Fiber Types
- Slow oxidative fibers: Slow contraction, postural muscles, sustained endurance
- Fast oxidative fibers: Fast contraction, some aerobic and anaerobic processes, sprinting/walking
- Fast glycolytic fibers: Fastest contraction, mostly anaerobic, eye muscles
Effects of Exercise on Skeletal Muscle
- Resistance training: Increased muscle fiber size (hypertrophy), more mitochondria, larger glycogen reserves, increased muscle fiber number (hyperplasia)
- Endurance training: Increased repetitions with lower weight, increased number of mitochondria, increased oxidative enzymes, more myoglobin
Aging and Skeletal Muscle
- Reduced muscle recovery, decreased satellite cells, fibrosis, decreased muscle mass, loss of muscle fibers and diameter
- Disuse atrophy: Reduction in muscle size due to lack of physical activity, loss of myofibrils
Exercise and Other Body Systems
- Body composition: Prevents obesity
- Cardiovascular system: Stronger heart pump, increased blood flow to tissue, decreased blood pressure
- Mental health: Enhanced learning and memory, lower risk of depression
- Immune system: Lower risk of cancer, increase immune cell activity
Reflex Arc
- Reflex arc is involuntary response, has sensory and motor components
- Components: Receptor, sensory neuron, integration center, motor neuron, effector
Muscle Spindle and Golgi Tendon Organs
- Muscle spindle: Detects muscle stretch, located between muscle cells
- Golgi tendon organ: Detects tension, located in tendons
Reflexes
- Myotatic reflex (stretch reflex): Muscle stretch activates muscle contraction, helps maintain posture
- Withdrawal reflex: Painful receptors activate flexor muscles to retract limb from danger
- Crossed-extensor reflex: Helps maintain balance during withdrawal reflex
Peripheral Nerve Injury
- Nerve injury can lead to sensory and motor issues, loss of muscle tone, abnormal reflexes
- Paresthesia: Abnormal pain, touch, or temperature sensation due to damage to sensory axons
- Atrophy: Damage to one motor unit leads to loss of muscle mass
- Paresis: Muscle weakness
- Paralysis: Complete muscle atrophy
- Hyporeflexia: Diminished reflexes
- Areflexia: Absence of reflexes
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Description
Test your knowledge on the structure and function of sensory and motor neurons, as well as spinal cord anatomy. This quiz will cover the roles of various neuron types, the arrangement of gray and white matter, and the protective layers of the spinal cord. Perfect for students of neuroscience and biology.