Neuroscience Quiz on Synaptic Communication

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Questions and Answers

What is the primary function of presynaptic neurons in synaptic communication?

  • Release neurotransmitters into the synaptic cleft (correct)
  • Initiate postsynaptic potential
  • Diffusion of neurotransmitters across the synaptic cleft
  • Receive neurotransmitters from postsynaptic neurons

What occurs during the synaptic delay?

  • The binding of neurotransmitters to receptors happens
  • The time taken for neurotransmitter release and receptor binding (correct)
  • Neurotransmitters are synthesized
  • Neurotransmitters diffuse across the synaptic cleft

Which of the following glial cells is NOT found in the central nervous system (CNS)?

  • Astrocytes
  • Schwann cells (correct)
  • Microglia
  • Oligodendrocytes

What is the purpose of neurotransmitter binding to postsynaptic receptors?

<p>To open ion channels and create graded potentials (C)</p> Signup and view all the answers

Which statement accurately describes the synaptic cleft?

<p>A fluid-filled space that separates presynaptic and postsynaptic neurons (D)</p> Signup and view all the answers

What is one of the primary functions of astrocytes in the CNS?

<p>Regulate substances reaching the CNS from the blood (D)</p> Signup and view all the answers

What do ependymal cells help to circulate within the CNS?

<p>CSF (Cerebrospinal fluid) (A)</p> Signup and view all the answers

Which type of neuroglial cell is responsible for myelin sheaths in the CNS?

<p>Oligodendrocytes (A)</p> Signup and view all the answers

Microglia are best described as what type of cell?

<p>Phagocytic cells that respond to infection (B)</p> Signup and view all the answers

What role do astrocytes play in neuronal development?

<p>They induce synapse formation (B)</p> Signup and view all the answers

What is the primary location of ependymal cells?

<p>Line the ventricles of the brain (D)</p> Signup and view all the answers

Which type of cell occupies the space of dying neurons and provides various functions in the CNS?

<p>Astrocytes (A)</p> Signup and view all the answers

What is a unique feature of oligodendrocytes in relation to axons?

<p>They can myelinate multiple axons (C)</p> Signup and view all the answers

What primarily determines whether a neurotransmitter has an excitatory or inhibitory effect?

<p>The receptor to which it binds (D)</p> Signup and view all the answers

What is the main function of acetylcholine (ACh) in the peripheral nervous system (PNS)?

<p>To stimulate skeletal muscle (B)</p> Signup and view all the answers

What type of receptors does acetylcholine bind to in order to cause an excitatory postsynaptic potential (EPSP)?

<p>Nicotinic receptors (B)</p> Signup and view all the answers

What is a key characteristic of neuromodulators?

<p>They affect the strength of synaptic transmission (A)</p> Signup and view all the answers

What occurs during the facilitation process in neuromodulation?

<p>Increased response in postsynaptic neuron (D)</p> Signup and view all the answers

In neuronal pools, what is the purpose of neural integration?

<p>To perform a common function by integrating neurons (B)</p> Signup and view all the answers

What effect results from inhibition in neuromodulation?

<p>Weaker response in postsynaptic neuron (D)</p> Signup and view all the answers

How do drugs generally influence neurotransmitter action at synapses?

<p>By mimicking the action of endogenous neurotransmitters (B)</p> Signup and view all the answers

What is the main characteristic of converging circuits in neural integration?

<p>They allow multiple inputs to converge on a single neuron. (A)</p> Signup and view all the answers

Which type of neural circuit is characterized by the spreading of information from one neuron to several others?

<p>Diverging (B)</p> Signup and view all the answers

What type of circuit utilizes feedback to create a cyclical pattern of activity?

<p>Reverberating circuit (C)</p> Signup and view all the answers

Which statement best describes parallel after discharge circuits?

<p>They allow inputs to be processed simultaneously over various paths. (C)</p> Signup and view all the answers

In which type of neuron structure are chemically gated channels typically found?

<p>Dendrites (B)</p> Signup and view all the answers

Which of the following ions is primarily involved in establishing the resting membrane potential (RMP) of a neuron?

<p>K+ (C)</p> Signup and view all the answers

What is the primary function of a myelin sheath in the peripheral nervous system (PNS)?

<p>To insulate axons and increase the speed of impulse conduction. (B)</p> Signup and view all the answers

Which glial cell type replicates in response to meningitis infection?

<p>Microglia (B)</p> Signup and view all the answers

What are the three general functions of the nervous system?

<p>Collect, process, and initiate responses to information (D)</p> Signup and view all the answers

Which part of the nervous system is responsible for processing and evaluating information?

<p>Integrative neurons (A)</p> Signup and view all the answers

What is the main function of sensory neurons?

<p>Carry impulses to the CNS (D)</p> Signup and view all the answers

Which type of neuron is most commonly found in the central nervous system?

<p>Multipolar neurons (C)</p> Signup and view all the answers

What structure encloses an entire peripheral nerve?

<p>Epineurium (B)</p> Signup and view all the answers

What characterizes the conductivity of neurons?

<p>Ability to propagat electrical signals (A)</p> Signup and view all the answers

What is a primary characteristic of multipolar neurons?

<p>Many dendrites and a single axon (D)</p> Signup and view all the answers

What is the role of neuroglia in the nervous system?

<p>Support and protect neurons (B)</p> Signup and view all the answers

Which statement about mixed nerves is true?

<p>They comprise both sensory and motor neurons. (C)</p> Signup and view all the answers

What are synapses primarily responsible for in the nervous system?

<p>Facilitating information transfer between neurons (C)</p> Signup and view all the answers

What type of transport moves materials away from the neuron cell body?

<p>Anterograde transport (A)</p> Signup and view all the answers

Which of the following is a characteristic of neurons?

<p>Extreme longevity (C)</p> Signup and view all the answers

What type of synapse involves the release of neurotransmitters across a synaptic cleft?

<p>Chemical synapse (A)</p> Signup and view all the answers

What primarily creates the unequal distribution of sodium and potassium ions across the neuronal membrane?

<p>Sodium/Potassium pump activity (D)</p> Signup and view all the answers

Which type of ion channel opens in response to a change in membrane potential?

<p>Voltage-gated channels (C)</p> Signup and view all the answers

What occurs when multiple excitatory postsynaptic potentials (EPSPs) summate at the axon hillock?

<p>Threshold is reached and an action potential is generated (C)</p> Signup and view all the answers

Which segment of a neuron contains voltage-gated Na+ and K+ channels?

<p>Conductive segment (C), Initial segment (D)</p> Signup and view all the answers

What is the resting membrane potential (RMP) of a typical neuron?

<p>-70 mV (B)</p> Signup and view all the answers

What happens during depolarization of a neuron during an action potential?

<p>Na+ enters the cell (B)</p> Signup and view all the answers

How do graded potentials differ from action potentials?

<p>Graded potentials are temporary changes in membrane potential (C)</p> Signup and view all the answers

Which principle states that an action potential is propagated down the axon without any decrease in intensity?

<p>All-or-none law (C)</p> Signup and view all the answers

What primarily drives the resting membrane potential of a neuron?

<p>Potassium ion efflux (C)</p> Signup and view all the answers

What is the consequence of an inhibitory postsynaptic potential (IPSP)?

<p>It makes the postsynaptic neuron more negative, inhibiting action potential generation (B)</p> Signup and view all the answers

What phenomenon allows for multiple excitatory or inhibitory inputs to affect the postsynaptic neuron's response?

<p>Summation (B)</p> Signup and view all the answers

What happens during the repolarization phase of an action potential?

<p>K+ channels open and Na+ exits (C)</p> Signup and view all the answers

What primarily influences the electrical current generated in neurons?

<p>Voltage and resistance (A)</p> Signup and view all the answers

Which factor increases the likelihood of reaching the threshold for action potential generation?

<p>Increasing frequency of EPSPs (D)</p> Signup and view all the answers

Flashcards

Nervous System Function 1

Collects information using sensory receptors that detect stimuli.

Nervous System Function 2

Processes and evaluates information, leading to sensations, memories, thoughts, and decisions using integrative neurons.

Nervous System Function 3

Initiates responses to the processed information, using motor neurons to signal effectors that carry out the responses.

CNS

Central Nervous System, containing the brain and spinal cord.

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PNS

Peripheral Nervous System, containing nerves that connect the CNS to other parts of the body.

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Sensory (Afferent) Division

Transmits sensory information from receptors to the CNS.

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Motor (Efferent) Division

Transmits impulses from the CNS to effector organs.

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Somatic Nervous System

Controls voluntary movements, connecting the CNS to skeletal muscles.

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Autonomic Nervous System

Controls involuntary actions, connecting the CNS to glands and smooth muscles.

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Neuron

Basic unit of the nervous system, receiving stimuli and transmitting action potentials.

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Neuroglia

Support and protect neurons within the nervous system.

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Epineurium

Connective tissue wrapping enclosing the entire nerve.

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Perineurium

Connective tissue wrapping around a fascicle (bundle) of nerve fibers.

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Endoneurium

Connective tissue covering an individual axon.

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Chemical Synapse

A junction where neurotransmitters are released to transmit signals between neurons or neurons and effectors.

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Chemical Synapse

A junction between two neurons where neurotransmitters facilitate communication.

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Synaptic Cleft

The small gap between two neurons in a chemical synapse.

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Neuroglia

Non-excitable supportive cells for neurons in the CNS and PNS.

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Astrocytes

A type of neuroglia in the CNS that cover neurons and blood vessels.

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Synaptic Delay

The time required for events at a chemical synapse (neurotransmitter release, diffusion, binding, etc.).

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Astrocyte Function

Astrocytes regulate substance passage from blood to the CNS, aid in substance metabolism, support neurons, and assist in neuron development.

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Ependymal Cells

Ependymal cells line the brain's ventricles and spinal cord's central canal, producing cerebrospinal fluid (CSF).

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Oligodendrocytes

Oligodendrocytes create myelin sheaths in the CNS, isolating and speeding up nerve impulse transmission.

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Microglia Function

Microglia are immune cells within the CNS, removing microorganisms and cellular debris.

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Blood Brain Barrier

The blood-brain barrier regulates what substances can reach the CNS from the bloodstream.

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Capillary

Part of the blood-brain barrier ; it is a tiny blood vessel.

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Myelin Sheath Function

Myelin sheath insulates axons, speeding up nerve impulse transmission.

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Neuroglial Cells Role

Neuroglial cells support and protect neurons within the central nervous system.

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Sodium (Na+) ions

The major extracellular positive ions, maintained by the sodium/potassium pump and ion channels in the cell membrane.

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Membrane Channels

Membrane proteins that control the membrane's selective permeability to ions.

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Leak Channels

Membrane ion channels that are always open, contributing to resting membrane potential.

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Chemically Gated Channels

Ion channels that open in response to a neurotransmitter binding.

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Voltage-Gated Channels

Ion channels that open in response to changes in membrane potential.

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Modality-Gated Channels

Ion channels that open in response to a specific sensory stimulus, like light, pressure, or temperature.

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Resting Membrane Potential (RMP)

The electrical potential difference across the neuron membrane when it's not transmitting a signal, typically around -70 mV.

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Graded Potentials

Small, short-lived changes in membrane potential that vary in magnitude and are localized.

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EPSP (Excitatory Postsynaptic Potential)

A graded potential that makes the neuron more likely to fire an action potential.

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IPSP (Inhibitory Postsynaptic Potential)

A graded potential that makes the neuron less likely to fire an action potential.

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Summation

The process of adding up multiple postsynaptic potentials to influence the neuron's firing.

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Action Potential

A large, rapid change in membrane potential that propagates down the axon.

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Depolarization

The process of the membrane potential becoming more positive during an action potential.

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Repolarization

The process of the membrane potential returning to a negative value after depolarization.

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Ohm's Law

Current = Voltage/Resistance (I = V/R). An important equation describing the relationship between electrical current, voltage and resistance.

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Neural Circuit - Converging

Multiple inputs coming together to affect a single neuron or neuronal pool.

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Neural Circuit - Diverging

A single neuron's signal spreading to multiple neurons or neuronal pools.

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Neural Circuit - Reverberating

A neural circuit that uses feedback to produce repeated cyclical activity.

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Neural Circuit - Parallel After Discharge

Signals transmitted simultaneously through multiple paths.

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Potentiation

Strengthening of synaptic connections within neuronal pools.

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Synaptic Connections

The patterns of communication between neurons.

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Function of Receptors

Receptors detect stimuli and initiate nerve impulses.

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Effectors

Organs that respond to nerve impulses (e.g., muscles, glands).

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Neurotransmitter Effects

Neurotransmitters can be excitatory or inhibitory, but the effect depends on the receptor.

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Neurotransmitter Action Types

Neurotransmitters can act directly on ion channels or indirectly through second messenger systems.

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Acetylcholine (ACh)

A neurotransmitter, often stimulating skeletal muscle and increasing arousal.

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Neuromodulation

Changes the strength of synaptic transmission without directly causing EPSPs or IPSPs.

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Facilitation (Neuromodulation)

Modulation that strengthens the response in a postsynaptic neuron.

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Clinical Neurotransmitter Modulation

Drugs can modulate neurotransmitter actions at synapses.

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Neuronal Pools

Groups of neurons working together to perform a function.

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Neural Integration in Pools

Neuronal pools integrate incoming information and communicate with other pools to generate output.

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