Neuroscience Quiz: Neurons and Communication

Choose a study mode

Play Quiz
Study Flashcards
Spaced Repetition
Chat to Lesson

Podcast

Play an AI-generated podcast conversation about this lesson

Questions and Answers

What role do microtubules play in neurons?

  • They synthesize neurotransmitters.
  • They serve as a transport system for proteins. (correct)
  • They provide structural support for dendrites.
  • They generate electrical signals.

Which part of the neuron is primarily responsible for receiving incoming information?

  • Nucleus
  • Myelin sheath
  • Axon
  • Dendrites (correct)

In the context of neuron communication, what is the synapse?

  • The main body of the neuron where signals are processed.
  • The site of energy production within the neuron.
  • The insulating layer around the axon that speeds up signal transmission.
  • The junction where a presynaptic neuron communicates with a postsynaptic neuron. (correct)

What structure in a neuron helps to protect and improve the efficiency of signal transmission?

<p>Myelin sheath (D)</p> Signup and view all the answers

Which part of a neuron can be considered the initial segment where action potentials are generated?

<p>Axon hillock (D)</p> Signup and view all the answers

Which phase of the membrane potential occurs when it becomes less negative than the resting potential?

<p>Depolarization (C)</p> Signup and view all the answers

What must be used to maintain ionic gradients across the membrane during a dynamic steady state?

<p>Metabolic energy (C)</p> Signup and view all the answers

In the Goldman-Hodgkin-Katz equation, what does Vm represent?

<p>Membrane potential (D)</p> Signup and view all the answers

Which type of neuron is primarily responsible for transmitting sensory information to the central nervous system?

<p>Pseudounipolar neurons (A)</p> Signup and view all the answers

What primarily determines the equilibrium potential of an ion at rest?

<p>Concentration gradient of the ion (A)</p> Signup and view all the answers

Which structural classification describes neurons with multiple processes extending from the cell body?

<p>Multipolar (D)</p> Signup and view all the answers

Which ion's equilibrium potential is primarily involved in repolarization of the membrane potential?

<p>Potassium (K+) (D)</p> Signup and view all the answers

What is the main physiological role of interneurons in the central nervous system?

<p>Connect sensory and motor pathways (D)</p> Signup and view all the answers

How does hyperpolarization affect the membrane potential?

<p>It becomes more negative (D)</p> Signup and view all the answers

Which neuron type is characterized by having two equal processes coming from the cell body?

<p>Bipolar (A)</p> Signup and view all the answers

What role do motor proteins play in axonal transport?

<p>They facilitate the movement of vesicles along the microtubules. (A)</p> Signup and view all the answers

What is the primary structure that facilitates the movement of motor proteins in neurons?

<p>Microtubule network (D)</p> Signup and view all the answers

In which direction can axonal transport occur?

<p>Both towards the soma and presynaptic terminal (B)</p> Signup and view all the answers

What is a significant consequence of the varicella zoster virus's movement along axonal pathways?

<p>It can cause shingles. (D)</p> Signup and view all the answers

How do graded potentials travel in a neuron?

<p>From dendrites or cell body to axon hillock (B)</p> Signup and view all the answers

What is the function of lysosomes in neurons?

<p>To digest old membrane components (C)</p> Signup and view all the answers

What initiates action potentials in a neuron?

<p>Graded potentials at the axon hillock (A)</p> Signup and view all the answers

What is the energy source required for motor proteins to function in axonal transport?

<p>ATP (C)</p> Signup and view all the answers

Which area of a neuron is primarily responsible for conducting electrical signals?

<p>Axon (B)</p> Signup and view all the answers

What characterizes the connection between individual neurons?

<p>Isolated units with no cytoplasmic continuity (A)</p> Signup and view all the answers

What primarily determines the direction of ion flow across the cell membrane?

<p>Concentration gradient (C)</p> Signup and view all the answers

Which ion is found in a higher concentration inside the cell compared to outside?

<p>K+ (A)</p> Signup and view all the answers

What effect do K+ leak channels have on resting membrane potential?

<p>They contribute to the negativity of the resting membrane potential. (A)</p> Signup and view all the answers

Which of the following best describes the distribution of Na+ and K+ in body fluids?

<p>Na+ is higher outside cells, K+ is higher inside. (B)</p> Signup and view all the answers

What role do negatively charged proteins play in intracellular fluid?

<p>They are impermeable and increase negativity. (D)</p> Signup and view all the answers

What is the primary function of the Na+-K+ ATPase pump?

<p>To maintain the resting membrane potential. (D)</p> Signup and view all the answers

Which component primarily acts as an insulator in the cell membrane?

<p>Phospholipid bilayer (D)</p> Signup and view all the answers

What happens when the concentration gradient and the electrical gradient are equal for K+?

<p>Net movement of K+ becomes zero. (D)</p> Signup and view all the answers

What is the main reason for the selective permeability of the plasma membrane?

<p>It restricts charged molecules and large polar molecules. (A)</p> Signup and view all the answers

In the resting membrane potential, what is a significant factor that keeps negative ions inside the cell?

<p>Attraction between positive and negative charges. (A)</p> Signup and view all the answers

How is the resting membrane potential described on a relative charge scale?

<p>Set at zero for extracellular fluid. (D)</p> Signup and view all the answers

What effect does the presence of more K+ leak channels than Na+ leak channels have?

<p>It facilitates the exit of K+ and contributes to a negative potential. (B)</p> Signup and view all the answers

Which ion primarily contributes to the electrical gradient needed for the resting membrane potential?

<p>K+ (C)</p> Signup and view all the answers

What is the primary ion that causes depolarization during stimulation of the plasma membrane?

<p>Na+ (B)</p> Signup and view all the answers

Which of the following describes the resting membrane potential?

<p>There are more negative charges inside than outside. (C)</p> Signup and view all the answers

What role does the Na+-K+ ATPase play in the cell?

<p>It maintains ionic concentration gradients. (A)</p> Signup and view all the answers

What is the correct formula for calculating the equilibrium potential for a single ion type?

<p>Eion = (61/z) log ([ion]extra / [ion]intra) (B)</p> Signup and view all the answers

What occurs after the depolarization phase during an action potential?

<p>Repolarization. (A)</p> Signup and view all the answers

What is used to counterbalance the efflux of K+ ions due to their concentration gradient?

<p>The negative equilibrium potential. (D)</p> Signup and view all the answers

What maintains the dynamic steady state of the cell at resting state?

<p>Active transport and passive leak of ions. (C)</p> Signup and view all the answers

Which factor primarily contributes to the negative value of the resting membrane potential?

<p>Higher concentration of K+ inside the cell. (D)</p> Signup and view all the answers

How does osmotic equilibrium relate to the membrane potential?

<p>Water movement stops, maintaining ionic distribution. (B)</p> Signup and view all the answers

Which ion type primarily exists at higher concentrations inside a living cell compared to the extracellular fluid?

<p>K+ (B)</p> Signup and view all the answers

What is the primary direction of signal flow for neurotransmission?

<p>Anterograde neurotransmission (B)</p> Signup and view all the answers

What is the osmolarity of the intracellular fluid based on the provided information?

<p>290 mOsm/L (A)</p> Signup and view all the answers

What process occurs at the presynaptic axon terminal before neurotransmitter release?

<p>Electrical conversion (C)</p> Signup and view all the answers

What role do dendritic spines play in synaptic communication?

<p>Enhance contact sites between neurons (C)</p> Signup and view all the answers

In terms of ion channels, which channel type is more prevalent during resting membrane potential?

<p>K+ leak channels. (C)</p> Signup and view all the answers

What characterizes the condition of a living cell at the resting membrane potential?

<p>It is a dynamic steady state. (C)</p> Signup and view all the answers

Which type of synapse is associated with excitatory connections?

<p>Spine heads (A)</p> Signup and view all the answers

What is retrograde transport in neurons?

<p>Transport of proteins from the dendrite back to the presynaptic terminal (A)</p> Signup and view all the answers

What type of signal is transmitted by dendrites to the cell body of a neuron?

<p>Electrical signals (A)</p> Signup and view all the answers

Which structure connects the presynaptic axon terminal and the postsynaptic dendrite?

<p>Synaptic cleft (D)</p> Signup and view all the answers

What is the significance of the presence of polyribosomes in dendritic spines?

<p>They enable protein synthesis within the spines. (C)</p> Signup and view all the answers

The integration of graded potentials occurs where in a neuron?

<p>Cell body (D)</p> Signup and view all the answers

What characterizes inhibitory synapses?

<p>Decreased likelihood of action potential generation (C)</p> Signup and view all the answers

What type of neurotransmission involves signals moving from the terminal to neighboring neurons?

<p>Anterograde neurotransmission (D)</p> Signup and view all the answers

What is the primary function of the myelin sheath?

<p>To speed up electrical signal transmission (C)</p> Signup and view all the answers

What is typically found at the synapse of a neuron?

<p>A mixture of electrical and chemical signals (C)</p> Signup and view all the answers

Flashcards

Resting Membrane Potential

The difference in electrical charge between the inside and outside of a cell membrane, when the cell is at rest.

Neuron

A specialized cell that transmits nerve impulses throughout the body.

Cell Membrane

The lipid bilayer that forms the outer boundary of a cell, controlling what enters and exits.

Electrolytes

Charged molecules, such as Na+, K+, Cl-, and Ca++, that are essential for many cellular processes.

Signup and view all the flashcards

Interstitial Fluid

The fluid that surrounds cells and tissues, containing electrolytes like Na+, Cl-, and HCO3-.

Signup and view all the flashcards

Intercellular Fluid

The fluid inside a cell, containing electrolytes like K+, phosphate ions, and negatively charged proteins.

Signup and view all the flashcards

Selective Permeability

The ability of a cell membrane to allow some substances to pass through while blocking others.

Signup and view all the flashcards

Concentration Gradient

The difference in the concentration of a substance between two areas, such as the inside and outside of a cell.

Signup and view all the flashcards

Electrical Gradient

The movement of ions across a membrane due to the difference in their electrical charges.

Signup and view all the flashcards

Na+-K+ ATPase

A protein pump that actively transports 3 sodium ions (Na+) out of the cell and 2 potassium ions (K+) into the cell, requiring energy.

Signup and view all the flashcards

K+ Leak Channels

Channels in the cell membrane that allow potassium ions (K+) to leak out of the cell, contributing to the resting membrane potential.

Signup and view all the flashcards

Equilibrium Potential

The theoretical voltage difference across a membrane when the movement of ions due to concentration gradient and electrical gradient are balanced, resulting in no net movement of ions.

Signup and view all the flashcards

Resting Membrane Potential

The negative charge inside a cell at rest, typically around -70 millivolts.

Signup and view all the flashcards

Nerve Impulse

The transfer of information along a nerve cell, which triggers a change in the membrane potential.

Signup and view all the flashcards

Neural Communication

The process by which a neuron receives, integrates, and transmits information.

Signup and view all the flashcards

Cytoskeleton in Neurons

A network of protein fibers, primarily microtubules, that extends throughout a neuron, providing structural support and facilitating the transport of molecules and organelles.

Signup and view all the flashcards

Dendrites

Thin extensions of a neuron that receive incoming signals from other neurons. They act like antennas, gathering information.

Signup and view all the flashcards

Axon

The main process of a neuron that sends signals to other cells. It is like a long cable transmitting information.

Signup and view all the flashcards

Synapse

The junction between an axon terminal and another neuron or target cell. Information is transferred across this gap through chemical signals.

Signup and view all the flashcards

Intracellular Transport in Neurons

The process of transporting molecules and organelles along microtubules within a neuron. It is essential for the neuron's function.

Signup and view all the flashcards

Dynamic Steady State

A state where a cell maintains stable internal conditions despite being in a dynamic, constantly changing environment.

Signup and view all the flashcards

Membrane Potential (Vm)

The difference in electrical potential between the inside and outside of a cell membrane.

Signup and view all the flashcards

Depolarization

A change in membrane potential that makes the inside of the cell less negative (more positive) relative to the resting membrane potential.

Signup and view all the flashcards

Repolarization

A change in membrane potential that returns the membrane potential back to its resting value after a depolarization event.

Signup and view all the flashcards

Hyperpolarization

A change in membrane potential that makes the inside of the cell more negative (less positive) relative to the resting membrane potential.

Signup and view all the flashcards

Nernst Equation

The equation that calculates the equilibrium potential for a specific ion across a membrane. It considers the concentration gradient of the ion.

Signup and view all the flashcards

Goldman-Hodgkin-Katz (GHK) Equation

The equation that calculates the membrane potential of a cell, considering the contributions of multiple ions and their relative permeabilities across the membrane.

Signup and view all the flashcards

Cell Body (Soma)

The central part of a neuron, containing the nucleus and other organelles.

Signup and view all the flashcards

What causes Resting Membrane Potential?

This electrical potential difference is created by the difference in concentration of ions (charged particles) across the plasma membrane.

Signup and view all the flashcards

Role of Potassium Ions

The movement of ions through the cell membrane, particularly potassium ions (K+), is a major contributor to the resting membrane potential.

Signup and view all the flashcards

Sodium-Potassium Pump

The sodium-potassium pump (Na+-K+ ATPase) actively pumps sodium ions (Na+) out of the cell and potassium ions (K+) into the cell, maintaining the concentration gradient across the membrane.

Signup and view all the flashcards

Equilibrium Potential (Eion)

The equilibrium potential for a specific ion is the electrical potential difference across the membrane that would be necessary to prevent the movement of that ion across the membrane from its current concentration gradient.

Signup and view all the flashcards

Calculating Equilibrium Potential

It can be calculated using the Nernst equation, which takes into account the concentration gradient and the valence of the ion.

Signup and view all the flashcards

Stimulation of Plasma Membrane

A process that changes the resting membrane potential of a cell.

Signup and view all the flashcards

Restoring Ionic Gradients

The sodium-potassium pump (Na+-K+ ATPase) plays a crucial role in restoring the ionic concentration gradients across the membrane after depolarization and repolarization, ensuring that the cell is prepared for another stimulus.

Signup and view all the flashcards

Maintaining Resting State

The cell's resting state is maintained by the balance between passive ion leak channels, particularly for potassium ions (K+), and the active pumping of sodium ions (Na+) out and potassium ions (K+) into the cell by the sodium-potassium pump.

Signup and view all the flashcards

Electrolyte Concentrations

The concentrations of major electrolytes in the interstitial fluid and intracellular fluid are different at rest, contributing to the resting membrane potential.

Signup and view all the flashcards

Osmotic Equilibrium

While there is this chemical and electrical disequilibrium, the two compartments are in osmotic equilibrium, meaning there is no net movement of water between them.

Signup and view all the flashcards

Importance of Resting Membrane Potential

The resting membrane potential is crucial for cell function, as it allows cells to respond to stimuli, generate action potentials, and maintain homeostasis.

Signup and view all the flashcards

Negative Charge Inside the Cell

The negative charge inside the cell is primarily due to the presence of negatively charged proteins and other organic molecules.

Signup and view all the flashcards

Motor proteins

Proteins that move organelles along microtubules, using ATP as an energy source.

Signup and view all the flashcards

Axonal transport

The process of transporting organelles and vesicles along the microtubule network within a neuron.

Signup and view all the flashcards

Anterograde axonal transport

Axonal transport that moves organelles and vesicles from the cell body towards the axon terminal.

Signup and view all the flashcards

Retrograde axonal transport

Axonal transport that moves organelles and vesicles from the axon terminal back to the cell body.

Signup and view all the flashcards

Axon hillock

The region within a neuron where action potentials are initiated and propagated along the axon.

Signup and view all the flashcards

Presynaptic terminal

The site where a neuron releases neurotransmitters to communicate with other neurons or cells.

Signup and view all the flashcards

Shingles

A type of infectious disease caused by the reactivation of the varicella zoster virus that uses anterograde axonal transport.

Signup and view all the flashcards

Graded potential

The gradual decrease in the strength of an electrical signal as it travels along a neuron, especially in the dendrites and cell body.

Signup and view all the flashcards

Anterograde Neurotransmission

The transmission of signals from a neuron to other neurons, usually occurring in the direction of the axon (forward movement).

Signup and view all the flashcards

Dendritic Spine

A specialized protrusion on a dendrite that increases the surface area available for receiving signals from other neurons.

Signup and view all the flashcards

Synaptic Transmission

The process of converting an electrical signal from the presynaptic neuron into a chemical signal (neurotransmitter) that can travel across the synaptic cleft to the postsynaptic neuron.

Signup and view all the flashcards

Neurotransmitter

Molecules released by the presynaptic neuron that bind to receptors on the postsynaptic neuron, triggering a change in the postsynaptic neuron's electrical state.

Signup and view all the flashcards

Dendritic Integration

The ability of a dendrite to receive signals from multiple neurons, which allows for complex integration of information.

Signup and view all the flashcards

Signal Integration

The process of combining multiple incoming signals from dendrites to generate a single output signal that travels down the axon.

Signup and view all the flashcards

Axon Initial Segment

The initial segment of the axon where the axon hillock connects to the axon proper.

Signup and view all the flashcards

Myelin Sheath

The fatty substance that insulates the axon and speeds up the conduction of electrical signals down the axon.

Signup and view all the flashcards

Long-Term Potentiation (LTP)

The process of strengthening synaptic connections, leading to enhanced communication between neurons.

Signup and view all the flashcards

Long-Term Depression (LTD)

The process of weakening synaptic connections, leading to reduced communication between neurons.

Signup and view all the flashcards

Synaptic Plasticity

Changes in the structure and function of synapses that occur as a result of learning and experience.

Signup and view all the flashcards

Neural Excitability

The ability of a neuron to respond to an electrical signal and generate an action potential.

Signup and view all the flashcards

Study Notes

Nervous System - Resting Membrane Potential and Neuron

  • Objectives:
    • Understand the basic principle of resting membrane potential generation.
    • Describe the anatomy of a typical neuron and its functions.

Membrane Permeability

  • Phospholipid bilayer of cell membranes are impermeable to charged molecules (e.g., Na+, K+, Cl-, Ca++).
  • These charged molecules are also insoluble in the hydrophobic membrane core.
  • Large water-soluble molecules (e.g., proteins, nucleic acids, sugars) also require channels to cross the membrane.
  • Small uncharged polar molecules (e.g., CO2, O2, NH3, water) can cross the membrane freely (often via aquaporins).

Electrolyte Distribution

  • Interstitial Fluid: Major electrolytes include Na+, Cl-, and HCO3-.
  • Intracellular Fluid: Major electrolytes include K+, HPO42- (phosphate ion), and negatively charged proteins.

Dominant Ions

  • Extracellular Fluid: Sodium (Na+) and Chloride (Cl-)
  • Intracellular Fluid: Potassium (K+) and negatively charged proteins.
  • The selective permeability of the plasma membrane causes uneven distribution of electrolytes, establishing an electrochemical disequilibrium.

Electrical Properties & Potential

  • Plasma membranes exhibit ionic conductance allowing ionic currents.
  • The concentration gradient dictates ion flow across the membrane.
  • The membrane acts as a capacitor, holding charges.
  • This electrical gradient creates a transmembrane potential (voltage difference between intra and extracellular spaces).
  • Resting membrane potential (RMP) is the potential across the membrane at rest.

Resting Membrane Potential (RMP)

  • When a cell is at rest, it maintains a negative membrane potential (-70 mV typically).
  • This is due to differences in ion concentrations inside and outside the cell.
  • The movement of sodium and potassium ions creates this negative value.
  • Na+/K+ ATPase maintains RMP by pumping 3 sodium ions out and 2 potassium ions in this process.

K+ Leak Channels

  • Cells have more potassium leak channels than sodium leak channels.
  • The concentration gradient pushes K+ out of the cell.
  • However, negative ions inside the cell oppose K+ efflux holding a negative resting value.

Equilibrium Potential

  • Equilibrium potential (Eion) is the membrane potential at which the concentration and electrical gradient for a specific ion are balanced.

  • The loss of positive ions (K+) intracellularly and the presence of -ve charged ions creates an electrical gradient.

  • The K+ concentration gradient and the electrical gradient cause an opposing force.

  • These forces balance each other, resulting in no net movement of K+ across the membrane.

Physiological Importance

  • Maintaining the resting membrane potential is crucial for cell function.
  • Maintaining the ionic gradients requires metabolic energy from the cell. This is essential for cellular function, especially for neurons, muscle cells, and other excitable cells.

Neuron Anatomy & Functions

  • Neuron: a nerve cell. This is the fundamental functional unit of the nervous system; responsible for transmitting and receiving information.

  • Anatomy: Neurons contain a cell body (soma), with dendrites, and an axon.

  • Functions:

    • Receiving signals from other neurons or sensory receptors.
    • Integrating information by processing signals.
    • Sending signals to other neurons, muscles, or glands.
  • Classification: Based on structure and function (sensory, interneurons, and motor).

  • Structural Classification: Multipolar (multiple processes), Bipolar (two processes), Unipolar (single process).

  • Functional Types: Sensory, Interneurons, Motor.

Parts of a Neuron

  • Cell Body (Soma): Contains the nucleus and organelles.
  • Axon: Extends from the cell body and carries signals in an outbound direction, with branches at the end (axon terminals).
  • Dendrites: Branching extensions of the neuron. They are the receiving end of signals.

Studying That Suits You

Use AI to generate personalized quizzes and flashcards to suit your learning preferences.

Quiz Team

More Like This

Nervous System and Neurons Quiz
8 questions
Nervous System Function and Neuron Structure
8 questions
Use Quizgecko on...
Browser
Browser