Podcast
Questions and Answers
What is the role of the interpositus nucleus in eyeblink conditioning?
What is the role of the interpositus nucleus in eyeblink conditioning?
- Initiating the eyeblink response directly
- Learning the relationship between the conditioned stimulus (CS) and the unconditioned stimulus (US) (correct)
- Learning the timing of the stimuli
- Controlling the release of glutamate in the cerebellar cortex
What is the effect of pairing firing of climbing fibers with parallel fibers in the cerebellar cortex?
What is the effect of pairing firing of climbing fibers with parallel fibers in the cerebellar cortex?
- Increase in PKC activity
- Increase in GABA release from Purkinje cells
- Increase in synaptic strength in climbing fiber input
- Decrease in synaptic strength in parallel fiber input (correct)
What cellular process is associated with long-term depression (LTD) in Purkinje cells?
What cellular process is associated with long-term depression (LTD) in Purkinje cells?
- Increase in NMDA receptor activity
- Increase in synaptic strength in parallel fiber input
- Increase in AMPA receptors in Purkinje neurons
- Decrease in AMPA receptors in Purkinje neurons (correct)
Which molecule is crucial for activating PKC alpha in cellular plasticity processes?
Which molecule is crucial for activating PKC alpha in cellular plasticity processes?
What happens to the response if Purkinje cells are blocked during eyeblink conditioning?
What happens to the response if Purkinje cells are blocked during eyeblink conditioning?
What is the function of the cerebellar cortex in associative conditioning according to the text?
What is the function of the cerebellar cortex in associative conditioning according to the text?
What is the role of the interpositus nucleus in eyeblink conditioning?
What is the role of the interpositus nucleus in eyeblink conditioning?
Which type of neurons receive inputs from granule cells via parallel fibers in the cerebellum?
Which type of neurons receive inputs from granule cells via parallel fibers in the cerebellum?
What is the effect of depression of inputs from granule cells on Purkinje cells?
What is the effect of depression of inputs from granule cells on Purkinje cells?
Which structure is responsible for learning the timing in eyeblink conditioning?
Which structure is responsible for learning the timing in eyeblink conditioning?
What neurotransmitter do Purkinje neurons release to prevent output neurons from firing?
What neurotransmitter do Purkinje neurons release to prevent output neurons from firing?
What is the evidence suggesting that LTD is caused by?
What is the evidence suggesting that LTD is caused by?
What mutation in mice engineered leads to the absence of LTD when climbing fibers and parallel fibers are coincidentally fired?
What mutation in mice engineered leads to the absence of LTD when climbing fibers and parallel fibers are coincidentally fired?
Which process is NOT necessary for eye-blink conditioning according to the text?
Which process is NOT necessary for eye-blink conditioning according to the text?
What is suggested as the cellular mechanism underlying memory formation in the text?
What is suggested as the cellular mechanism underlying memory formation in the text?
What is necessary for the timing of eyeblink conditioning?
What is necessary for the timing of eyeblink conditioning?
Which mutation allows mice to have normal eye-blink conditioning despite the absence of LTD?
Which mutation allows mice to have normal eye-blink conditioning despite the absence of LTD?
