Neuroscience Chapter Review Quiz
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Questions and Answers

The ______ are small gaps of exposed axon, between the segments of myelin sheath, where action potentials take place.

nodes of Ranvier

The primary gustatory taste area in the frontal lobe is located in the insula.

True (A)

Which of the following is NOT a factor that contributes to sensory-specific satiety?

  • The decrease in the appeal of the food
  • Eating a large quantity of a specific food
  • The release of hormones like leptin (correct)
  • Repeated exposure to the same flavor

Explain the mechanism by which we taste salt.

<p>Sodium ions enter taste cells via sodium channels in the cell membrane, causing depolarization and the release of neurotransmitters. A variant of the TRPV1 receptor can also detect sodium and other positively charged ions.</p> Signup and view all the answers

Match the following terms with their descriptions:

<p>Nodes of Ranvier = Small gaps of exposed axon Action potential = Neural impulse travelling along the axon Learned taste aversion = Avoidance of food associated with illness Area postrema = Brain region outside the blood-brain barrier Duodenum = Initial 25cm of the small intestine</p> Signup and view all the answers

The absorptive phase refers to the period when the body relies on energy stores.

<p>False (B)</p> Signup and view all the answers

How does the brain respond when toxins enter the bloodstream?

<p>The area postrema, located outside the blood-brain barrier, detects toxins and triggers vomiting to expel them from the body.</p> Signup and view all the answers

Which of the following taste receptors is NOT metabotropic?

<p>Sour (B)</p> Signup and view all the answers

What is the primary excitatory neurotransmitter in the nervous system?

<p>Glutamate (B)</p> Signup and view all the answers

The enteric nervous system (ENS) does not exhibit plasticity or learning.

<p>False (B)</p> Signup and view all the answers

What are the three main components of the brain stem?

<p>Medulla, pons, and midbrain</p> Signup and view all the answers

Which of the following structures increases the surface area of the small intestine for better absorption?

<p>Both c and B (D)</p> Signup and view all the answers

The ______ is the primary sensory relay point in the brain for stimuli from the respiratory, cardiovascular, and gastrointestinal systems.

<p>nucleus of the solitary tract</p> Signup and view all the answers

Mechanical digestion only occurs in the mouth.

<p>False (B)</p> Signup and view all the answers

Match the following brain structures with their primary functions:

<p>Hypothalamus = Gateway to cortex; relays sensory information (except smell) Hippocampus = Memory storage and conversion of short-term to long-term memory Thalamus = Homeostasis, motivated behaviors, link between nervous and endocrine systems Amygdala = Emotional regulation, motivation, memory formation, responses to sensory stimuli</p> Signup and view all the answers

What is the name of the mixture of partially digested food and enzymes found in the stomach?

<p>Chyme</p> Signup and view all the answers

Which of the following is NOT a function often associated with the hypothalamus?

<p>Control of voluntary muscle movements (B)</p> Signup and view all the answers

The process of wave-like muscle contractions that move food through the digestive tract is called ______.

<p>Peristalsis</p> Signup and view all the answers

Match the digestive enzyme with its corresponding action:

<p>Salivary Amylase = Begins breakdown of starches Lingual Lipase = Begins breakdown of lipids Pepsin = Begins breakdown of proteins Pancreatic Lipase = Digests fats after emulsification by bile</p> Signup and view all the answers

The limbic system is primarily responsible for controlling sensory perception.

<p>False (B)</p> Signup and view all the answers

Which of the following is NOT a component of gastric juice?

<p>Pancreatic Lipase (A)</p> Signup and view all the answers

What is the term used to describe the state of maintaining a balanced internal environment within the body?

<p>Homeostasis</p> Signup and view all the answers

The large intestine is primarily responsible for absorbing nutrients from digested food.

<p>False (B)</p> Signup and view all the answers

What is the main role of bile in digestion?

<p>Emulsifying fats</p> Signup and view all the answers

What is the primary role of villi in the digestive system?

<p>Villi are small, finger-like projections that line the small intestine. They increase the surface area for absorption of nutrients into the bloodstream and lymph.</p> Signup and view all the answers

Which of the following is NOT a function of the gut microbiome?

<p>Regulation of blood pressure (D)</p> Signup and view all the answers

The appendix is considered a vestigial organ with no known function.

<p>False (B)</p> Signup and view all the answers

Bile is produced in the ______ and helps to ______ fats and oils.

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Which of the following nuclei in the hypothalamus are involved in eating behavior?

<p>All of the above (D)</p> Signup and view all the answers

Leptin and insulin act in the brain to stimulate eating.

<p>False (B)</p> Signup and view all the answers

Prader-Willi syndrome patients have grossly increased levels of the hormone ______, which is known to stimulate appetite.

<p>ghrelin</p> Signup and view all the answers

What are the three main stages of each meal?

<ol> <li>Hunger, 2. Motivation, 3. Stop eating</li> </ol> Signup and view all the answers

Match the following chemicals with their role in appetite regulation:

<p>Neuropeptide Y (NPY) = Anorexigenic Agouti-related protein (AgRP) = Anorexigenic Cocaine and amphetamine regulated transcript (CART) = Orexigenic Alpha-melanocyte-stimulating hormone (α-MSH) = Orexigenic</p> Signup and view all the answers

Glutamate is a neurotransmitter released by ARC neurons that acts as an orexigenic signal, promoting appetite.

<p>False (B)</p> Signup and view all the answers

Which of the following is NOT a key function of the arcuate nucleus in the hypothalamus?

<p>Regulating body temperature (C)</p> Signup and view all the answers

What is the field of nutritional genomics focused on?

<p>The science of how nutrients affect gene activities and how genes affect nutrient activities.</p> Signup and view all the answers

Which of the following hormones is primarily secreted from the jejunum, the second segment of the small intestine, and has inhibitory effects on eating?

<p>Glucagon-like peptide 1 (GLP-1) (A)</p> Signup and view all the answers

Pancreatic peptide (PP) is released in proportion to calories consumed and can reduce food intake in both normal and obese individuals.

<p>True (A)</p> Signup and view all the answers

What is the primary target of GLP-1, and how does it affect food intake?

<p>GLP-1 targets the stomach, slowing gastric emptying and increasing satiety.</p> Signup and view all the answers

The hormone ______ is secreted from the ileum, the final segment of the small intestine, and has inhibitory effects on eating.

<p>Peptide YY (PYY)</p> Signup and view all the answers

Match the following hormones with their primary sites of action for regulating food intake:

<p>Cholecystokinin (CCK) = Brain stem Glucagon-like peptide 1 (GLP-1) = Stomach Peptide YY (PYY) = Arcuate nucleus of the hypothalamus Pancreatic peptide (PP) = Hypothalamus and brain stem</p> Signup and view all the answers

Synethesia refers to the experience of one type of sensation being perceived as another, such as seeing colors when hearing sounds.

<p>True (A)</p> Signup and view all the answers

How does CCK contribute to feelings of fullness after eating?

<p>CCK slows gastric emptying, leading to increased gastric distension, which makes us feel fuller, particularly in the top third of the stomach.</p> Signup and view all the answers

Which of the following is NOT an effect of CCK?

<p>Increased production of gastric acid (D)</p> Signup and view all the answers

The appendix is considered more useful than previously thought.

<p>True (A)</p> Signup and view all the answers

At what age is the gut microbiome generally considered balanced?

<p>2-3 years old</p> Signup and view all the answers

The process of absorbing nutrients mainly occurs in the ______.

<p>small intestine</p> Signup and view all the answers

Match the following immune cells with their primary functions:

<p>T Cells = Attack antigens B Cells = Produce antibodies Phagocytes = Engulf and destroy antigens Lymphocytes = Involved in immune response</p> Signup and view all the answers

What is the estimated number of microbes living in a healthy GI tract?

<p>100 trillion (D)</p> Signup and view all the answers

Microbial dysbiosis is characterized by greater diversity in the gut microbiome.

<p>False (B)</p> Signup and view all the answers

Bile emulsifies ______ and oils to prepare them for digestion.

<p>fats</p> Signup and view all the answers

Flashcards

Nodes of Ranvier

Small gaps of exposed axon between myelin segments where action potentials occur.

Action Potential

A neural impulse traveling along the axon causing chemical release from terminal buttons.

Insula

The primary gustatory taste area located in the frontal lobe of the brain.

Sensory-Specific Satiety

The phenomenon where the more you eat a certain food, the less appealing it becomes.

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Learned Taste Aversion

The avoidance of food associated with illness or negative experiences.

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Area Postrema

A brain region outside the blood-brain barrier that helps induce vomiting when toxins enter the bloodstream.

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Absorptive Phase

The stage after eating when the body uses nutrients from food for energy.

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T1R

A family of taste receptor proteins responsible for detecting sweet and umami flavors.

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Glutamate

The primary excitatory neurotransmitter in the nervous system.

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Enteric Nervous System (ENS) Plasticity

The ENS adapts and learns in response to dietary changes or gut disruptions.

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Gut Motility

Coordinated movements of muscles in the GI tract to propel contents.

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Nucleus of the Solitary Tract

Primary sensory relay point in the brain receiving signals from respiratory, cardiovascular, and GI systems.

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Hypothalamus

Regulatory brain structure that links the nervous and endocrine systems, maintaining homeostasis.

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Homeostasis

The body's tendency to maintain a balanced internal state.

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Thalamus

Gateway to the cortex, relaying sensory information except smell.

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Hippocampus

Brain region involved in memory storage and converting short-term memory to long-term.

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Villi

Fingerlike projections that increase intestinal surface area.

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Microvilli

Tiny hair-like projections on villi that further increase surface area.

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Digestion

The process of breaking food down into absorbable units.

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Peristalsis

Wavelike muscle contractions that move food through the digestive tract.

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Feces

Waste material after digestion and absorption is complete.

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Chyme

A mixture of enzymes and partially digested food in the stomach.

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Segmentation

Alternating movement that mixes food with intestinal juices.

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Chemical digestion

Enzymatic breakdown of food into small molecules for absorption.

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Absorption

Nutrients are absorbed through villi into the bloodstream and lymph, mainly in the small intestine.

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Gut Microbiome

A community of microbes in the GI tract that aids in digestion and immune function.

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Bile

A substance that emulsifies fats and oils to prepare them for digestion.

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Antigen

A foreign substance or microbe that triggers an immune response.

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Lymphocytes

White blood cells (B cells and T cells) involved in the immune response.

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Phagocytes

White blood cells that engulf and destroy antigens through phagocytosis.

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Sensation vs Perception

Sensation is detection of stimuli; perception is interpreting and making sense of that stimuli.

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Microbial Dysbiosis

An imbalance in the gut microbiome leading to decreased diversity.

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Intestine

A long tubular organ of digestion and site of nutrient absorption.

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Nutritional Genomics

The science of how nutrients affect genes and vice versa.

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Arcuate Nucleus

Hypothalamic area that drives hunger and initiates eating.

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Orexigenic Chemicals

Biochemicals that promote eating, e.g., neuropeptide Y.

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Anorexigenic Chemicals

Biochemicals that stop eating, such as CART.

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Three Stages of Eating

  1. Hunger, 2. Motivation, 3. Stop eating.
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Paraventricular Nucleus

Hypothalamic region involved in termination of eating.

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POMC Neurons

Neurons releasing chemicals like POMC and MSH that regulate appetite.

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Pancreatic Peptide (PP)

Hormone produced in pancreatic islets and distal gut that reduces food intake.

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Cholecystokinin (CCK)

Hormone from the duodenum that inhibits eating and stimulates gallbladder contraction.

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GLP-1

Hormone from jejunum that slows stomach emptying and increases satiety.

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Peptide YY (PYY)

Hormone secreted from the ileum that inhibits food intake, produced by L cells.

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Genetics

The study of heredity and how traits are passed along via genes.

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Dominant Gene

A gene expressed in the offspring whenever present, affecting traits.

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Recessive Gene

A gene expressed only when paired with a similar gene from the other parent.

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Genotype

The genetic constitution or makeup of an organism at conception.

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Study Notes

Neuron Basic Information

  • Neurons are the functional units of the brain, specialized for communication.
  • The human brain contains approximately 86 billion neurons.

Oxyntomodulin (OXM)

  • OXM is produced by processing GLP in both the gut and brain (similar to GLP-1).
  • It is released after eating, influencing nutrient ingestion and reducing food intake.

Basal Ganglia

  • Basal ganglia are subcortical structures crucial for initiating planned movements.

Neuron Operation

  • Neurons communicate through electrical impulses and chemical signals.
  • They receive, integrate, and transmit information throughout the nervous system.

Neuron Types

  • Sensory neurons (afferent) detect information from the physical world and transmit it to the brain.
  • Motor neurons (efferent) direct muscles (somatosensory) to contract or relax, causing movement.
  • Interneurons communicate only with other neurons, primarily within a specific brain region.

Neuron Development

  • Neuron networks develop through genetic influences, experience, maturation, and repeated firing.

Neuron Structure

  • Dendrites are branched extensions that receive information from other neurons.
  • The cell body processes information from thousands of neurons.
  • Axons are long, narrow extensions that transmit information to other neurons.
  • Terminal buttons are small knobs at the axon's ends that release chemical signals into the synapse.

Synaptic Communication

  • Neurons communicate with each other across synapses using neurotransmitters.
  • Neurotransmitters bind to receptors on the postsynaptic neuron.
  • Receptors can be excitatory (increase firing) or inhibitory (decrease firing).
  • Three major processes terminate the neurotransmitter's influence: reuptake, enzyme deactivation, and autoreception.

Neuron Communication

  • The synapse is the space between neurons where neurotransmitters are released to transmit signals.

Neurons to Behavior

  • Neurons communicate to form pathways that transmit information to various brain regions, leading to behavior (sensation, thought, action).
  • The sympathetic nervous system activates the "fight or flight" response in response to stressors.

Neuron Functions

  • Reception: receiving signals from other neurons
  • Conduction: integrating incoming signals
  • Transmission: sending signals to other neurons

Synapse

  • The synapse is the gap between neurons across which neurotransmitters transmit signals.

Receptors

  • Receptors on the postsynaptic neuron bind to neurotransmitters, triggering either excitation or inhibition.

Neurotransmitter Effects

  • Neurotransmitters can be either excitatory or inhibitory, depending on the specific receptor.

Removing Neurotransmitters

  • Reuptake, enzyme deactivation, and autoreception remove neurotransmitters from the synapse, stopping their influence.

Autoreceptors

  • Autoreceptors are receptors on the presynaptic neuron that monitor the amount of neurotransmitter released into the synapse.

Postsynaptic vs. Presynaptic Neurons

  • Presynaptic neurons send signals, while postsynaptic neurons receive them.

Neurotransmitters

  • Neurotransmitters are chemical messengers that carry signals between neurons.

Glycogen

  • Glycogen is the storage form of glucose (carbohydrate energy) in the body's tissues.

Adipose Tissue

  • Adipose tissue is the body's fat tissue, consisting of masses of fat-storing cells.

Moderate Drinkers

  • A moderate drinker is someone who does not drink excessively or inappropriately as a result of alcohol consumption.
  • Moderate drinking, for males, may involve two drinks per day.
  • Moderate drinking, for females, may involve one drink per day.

Effects of Alcohol

  • Alcohol can cause malnutrition, vitamin deficiencies, anemia, dehydration, and various gastritis, pancreatitis, and esophagitis.
  • Alcohol ingestion can result in the atrophy of the primary sex functions, testicular atrophy, spontaneous abortion, and amenorrhea.

Nutrition

  • Nutrition is the study of foods and nutrients, their composition, and bodily effects.
  • Factors influencing food choices include personal preferences, habit, ethnic background, and social interactions.

Functional Foods

  • Functional foods contain nutritionally active compounds that provide health benefits beyond basic nutrients.

Phytochemicals

  • Phytochemicals are non-nutrient plant-derived compounds with biological activity.

Neurotransmitters and Receptors

  • Neurotransmitters and their receptors are key-lock mechanisms
  • Many receptors exist for a single neurotransmitter, allowing for varied functions.

Agonists and Antagonists

  • Agonists increase the action of neurotransmitters.
  • Antagonists decrease the action of neurotransmitters or block their release.

Hormonal Messengers

  • Hormones are chemical messengers released by glands.
  • They travel through the bloodstream to target tissues and influence them.

Endocrine Glands

  • Endocrine glands such as the thyroid gland, parathyroid gland, pituitary gland, adrenal glands, pancreas, ovaries, or testes all produce hormones.

Hormone/Neurotransmitter Differences

  • Hormones are released into the bloodstream, influencing organs and systems.
  • Neurotransmitters are released between neurons in the synapse.

Brain-Stem Regions

  • The brain stem includes the medulla, pons, and midbrain. These regions control basic functions like breathing, heart rate, and swallowing.

Solitary Tract Nucleus

  • Solitary tract nucleus relays sensory signals from the digestive, respiratory, and cardiovascular systems.

Hypothalamus

  • In the brain, the hypothalamus regulates homeostatic functions and behavior.
  • The hypothalamus is the major regulatory center of eating behavior.
  • It contains areas involved in hunger and satiety.

Homeostasis

  • Homeostasis is the tendency of the body to maintain relatively stable internal states.

Thalamus & Limbic System

  • The thalamus is a relay station for sensory information, except for smell.
  • The limbic system is involved in emotional regulation, memory formation, and responses to stimuli.

Hippocampus & Cerebral Cortex

  • The hippocampus is involved in memory formation.
  • The cerebral cortex is the outer layer of the brain, involved in higher-level processes.

Lobes of the Cerebral Cortex

  • The occipital lobe processes visual information.
  • The parietal lobe is involved in touch and attention.

Olfactory (Smell) System

  • Odorants enter the nasal cavity.
  • Olfactory receptors (ORCs) in the olfactory epithelium detect odorants.
  • Smell signals travel to the olfactory bulb, then to other brain regions, such as the amygdala and hippocampus.

Taste System

  • Receptors for different tastes are located on the tongue. They send signals to the brain to create flavor.
  • There are five basic tastes: sweet, sour, salty, bitter, and umami.

Gustatory Cortex

  • The primary gustatory cortex is located in the frontal operculum and ventral insula.
  • A secondary gustatory cortex is located within the orbitofrontal cortex.

Flavor

  • Flavor is the integrated perception of taste, smell, texture, and appearance.

Satiation

  • Satiation is the feeling of fullness or satisfaction after a meal.

Hunger

  • Hunger is the feeling of wanting to eat.

Tonic & Episodic Regulation

  • Tonic regulation is for long-term signals of satiety and hunger.
  • Episodic regulation refers to signals for short-term satiation and hunger.

Hormones in Eating Regulation

  • Insulin and leptin are important hormones for hunger/satiety regulation.

Gut Hormones

  • Hormones from the gut, like ghrelin, GLP-1, and PYY, play a role in appetite regulation.

Macronutrients and Micronutrients

  • Macronutrients (carbohydrates, fats, and proteins) provide energy.
  • Micronutrients (vitamins and minerals) are essential for bodily functions.

Food Additives and Preservation

  • Food additives often support food quality, but are not required for basic nutrition.

Genetic and Environmental Influences

  • Genetic factors play a role in individual variations in nutrient needs and food preferences but can also vary based on external factors.

Nutrient density

  • Nutrient density refers to the amount of nutrients in a food related to the quantity of energy.

Genotype & Phenotype

  • Genotype refers to a person's genetic makeup.
  • Phenotype refers to the observable characteristics produced by that genetic makeup.

Twins

  • Monozygotic twins are genetically identical.
  • Dizygotic twins share about half of the same genes.

Sensory System Analysis

  • Sensory systems involve hierarchies with progressively complex analysis levels.
  • Sensory information is processed to understand sensory details and sensations.

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Description

Test your knowledge on the key concepts of neuroscience, including the structure of neurons, brain functions, and sensory systems. This quiz covers the roles of nerves, taste receptors, and neurotransmitters as well as specific processes that occur within the nervous system. Challenge yourself and reinforce your understanding of these vital topics!

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