Neuroscience Chapter Overview
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Questions and Answers

What is the primary function of the dorsal horn in the spinal cord?

  • To regulate bladder function
  • To form the cauda equina
  • To receive sensory input from peripheral neurons (correct)
  • To transmit motor impulses to muscles
  • Which of the following spinal cord regions contains motor neurons that exit the spinal cord?

  • Ventral horn (correct)
  • Dorsal root
  • Ascending tracts
  • Conus medullaris
  • How many pairs of spinal nerves originate from the spinal cord?

  • 31 (correct)
  • 24
  • 42
  • 28
  • What does the cauda equina consist of?

    <p>Roots of lumbar and sacral spinal nerves (D)</p> Signup and view all the answers

    Which spinal tract is primarily responsible for carrying motor impulses?

    <p>Corticospinal tract (A)</p> Signup and view all the answers

    What is the primary function of the spinal cord within the central nervous system?

    <p>Coordination of reflexes (D)</p> Signup and view all the answers

    Which part of the brain is most associated with consciousness and complex functions?

    <p>Cerebrum (C)</p> Signup and view all the answers

    What structure separates the two halves of the cerebrum?

    <p>Longitudinal fissure (B)</p> Signup and view all the answers

    Where is the majority of neural cell bodies located within the cerebrum?

    <p>Cerebral cortex (C)</p> Signup and view all the answers

    Which part of the brainstem is responsible for vital functions such as breathing and heart rate?

    <p>Medulla oblongata (B)</p> Signup and view all the answers

    What is the primary function of Broca's area?

    <p>Coordinates muscular actions of mouth and tongue for speech (B)</p> Signup and view all the answers

    Which area is primarily responsible for interpreting sensory information related to temperature, touch, pressure, and pain in the skin?

    <p>Anterior portion of parietal lobe (B)</p> Signup and view all the answers

    What is the role of the reticulospinal and rubrospinal tracts?

    <p>Maintain balance and posture (C)</p> Signup and view all the answers

    Which area is associated with understanding and producing language?

    <p>Wernicke's area (C)</p> Signup and view all the answers

    Where do sensory fibers typically cross over in the nervous system?

    <p>Spinal cord or brain stem (B)</p> Signup and view all the answers

    Which part of the brain is primarily responsible for muscle control, including balance and movement?

    <p>Cerebellum (D)</p> Signup and view all the answers

    What function is primarily associated with the supplementary motor cortex?

    <p>Planning and coordination of complex movements (D)</p> Signup and view all the answers

    What is the main function of the reticular activating system (RAS)?

    <p>Keeps the cerebral cortex conscious and alert (A)</p> Signup and view all the answers

    The frontal eye field is primarily responsible for which of the following?

    <p>Controlling eye and eyelid movements (D)</p> Signup and view all the answers

    Which structure is NOT part of the limbic system?

    <p>Cerebellum (B)</p> Signup and view all the answers

    Which cortex is specifically associated with transforming visual information into motor commands?

    <p>Parietal-lobe association cortex (C)</p> Signup and view all the answers

    What primarily changes in long-term memory to enhance synaptic transmission?

    <p>Neuronal structure or function (A)</p> Signup and view all the answers

    What is the term used for the sensation experienced that relates to pressure, pain, or warmth anywhere in the body?

    <p>Somatosensory function (D)</p> Signup and view all the answers

    Which part of the brainstem is responsible for relaying impulses between the motor cortex and the cerebellum?

    <p>Pons (B)</p> Signup and view all the answers

    Which lobe is primarily responsible for vision?

    <p>Occipital lobe (B)</p> Signup and view all the answers

    Which cranial nerves are associated with the medulla oblongata?

    <p>X, XI, XII (C)</p> Signup and view all the answers

    What is the role of the thalamus in sensory information processing?

    <p>Filters and relays information to the cerebral cortex (A)</p> Signup and view all the answers

    What primarily occurs during long-term synaptic potentiation in the hippocampus?

    <p>Enhanced synaptic transmission through structural changes (A)</p> Signup and view all the answers

    What is the function of the cardiovascular control center located in the medulla oblongata?

    <p>Adjusts heart contraction force and rate (C)</p> Signup and view all the answers

    Which part of the brain is located between the diencephalon and the pons?

    <p>Midbrain (D)</p> Signup and view all the answers

    What causes the photic sneeze reflex?

    <p>Overstimulation of the optic nerve triggering the trigeminal nerve (B)</p> Signup and view all the answers

    Which statement best describes Alzheimer's disease?

    <p>A neurodegenerative disease characterized by progressive loss of higher function (B)</p> Signup and view all the answers

    What is a common symptom of Huntington's disease?

    <p>Jerky and uncoordinated movements (B)</p> Signup and view all the answers

    What occurs during a transient ischemic attack (TIA)?

    <p>Temporary loss of blood flow to the brain (B)</p> Signup and view all the answers

    What type of paralysis results from severe damage to the ventral root or anterior horn cells?

    <p>Flaccid paralysis (C)</p> Signup and view all the answers

    What is a symptom of poliomyelitis?

    <p>Loss of somatic reflexes (A)</p> Signup and view all the answers

    What is the result of cross-sectioning of the spinal cord?

    <p>Total motor and sensory loss in regions inferior to the cut (B)</p> Signup and view all the answers

    What is a major result of amyotrophic lateral sclerosis (ALS)?

    <p>Loss of the ability to speak, swallow, and breathe (A)</p> Signup and view all the answers

    What is the primary function of the filum terminale?

    <p>To stabilize and protect the distal spinal cord (C)</p> Signup and view all the answers

    Which parts make up a spinal nerve after it emerges from the spinal cord?

    <p>Dorsal ramus, ventral ramus, meningeal branch (C)</p> Signup and view all the answers

    Which spinal nerves contribute to the brachial plexus?

    <p>C5-C8 and T1 (C)</p> Signup and view all the answers

    What nerve is primarily responsible for innervating the diaphragm?

    <p>Phrenic nerve (A)</p> Signup and view all the answers

    What is the largest nerve in the body and its function?

    <p>Sciatic nerve; innervates the buttocks and lower limb (A)</p> Signup and view all the answers

    What is a dermatome?

    <p>A area of skin supplied by sensory nerve fibers (C)</p> Signup and view all the answers

    Which of the following is true about reflexes?

    <p>Reflex arcs consist of five components (A)</p> Signup and view all the answers

    What does the mnemonic 'DARM' refer to in the context of spinal nerves?

    <p>Dorsal ramus, Anterior ramus, Meningeal branch (D)</p> Signup and view all the answers

    Which nerves innervate the anterior neck muscles?

    <p>Cervical plexus fibers (B)</p> Signup and view all the answers

    What is the function of the lumbar plexus?

    <p>Innervates the lower limb and abdominal wall (D)</p> Signup and view all the answers

    Which spinal nerve root supplies the skin over the belly button?

    <p>T10 (A)</p> Signup and view all the answers

    Which reflex is described as an involuntary response to a stimulus?

    <p>Patellar reflex (B)</p> Signup and view all the answers

    Which condition is associated with injury to the sciatic nerve?

    <p>Sciatica (B)</p> Signup and view all the answers

    Which of the following best describes the role of dermatomes in medical diagnostics?

    <p>To localize sites of injuries to dorsal roots (B)</p> Signup and view all the answers

    What is the primary factor in the mammalian diving reflex?

    <p>Bradycardia (A)</p> Signup and view all the answers

    Flashcards

    Cerebrum Function

    The cerebrum is the largest part of the brain, responsible for conscious experiences and regulating homeostasis.

    Cerebral Cortex

    The outer layer of the cerebrum, composed of gray matter and containing a significant portion of the nervous system's nerve cell bodies.

    Corpus Callosum

    A pathway of white matter in the cerebrum connecting the right and left cerebral hemispheres.

    Brain Regions

    The brain is divided into four major regions: cerebrum, diencephalon, brainstem, and cerebellum.

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    Diencephalon

    A part of the forebrain, located beneath the cerebrum.

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    Corticospinal Fibers

    Nerve fibers that travel from the cerebral cortex to the spinal cord, controlling voluntary muscle movements.

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    Motor Neurons

    Nerve cells that transmit signals from the spinal cord to muscles, causing them to contract.

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    Reticulospinal Tract

    A pathway in the spinal cord responsible for maintaining balance and posture.

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    Rubrospinal Tract

    A pathway in the spinal cord that helps control fine motor movements and posture.

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    Broca's Area

    A region in the left cerebral hemisphere that controls speech production.

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    Frontal Eye Field

    An area in the frontal lobe responsible for voluntary eye movements.

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    Wernicke's Area

    A region in the left hemisphere responsible for understanding spoken language.

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    Sensory Areas

    Brain regions that receive and interpret sensory information from the body.

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    Somatosensory Cortex

    A brain area responsible for processing touch, temperature, pain, and pressure sensations.

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    Association Areas

    Brain regions that analyze and interpret sensory information, helping with memory, reasoning, and judgment.

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    What is the function of the dorsal horn?

    The dorsal horn receives sensory input from peripheral neurons. It is responsible for receiving sensory information from the body.

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    What is the function of the ventral horn?

    The ventral horn contains motor neurons that exit the spinal cord to innervate skeletal muscle. It sends signals to muscles to move.

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    Cauda Equina

    A bundle of spinal nerves extending beyond the end of the spinal cord. It carries nerve signals to and from the legs.

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    Conus Medullaris

    The tapered end of the spinal cord. It regulates bladder function and lower extremity movement and sensation.

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    Spinal Nerves: What are they?

    31 pairs of mixed nerves originating from the spinal cord. They connect the spinal cord to upper and lower limbs, neck, and trunk.

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    Short-Term Memory

    Temporary storage of information, primarily electrical in nature. It holds a limited amount of information for a short time (seconds to minutes).

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    Long-Term Memory

    Permanent storage of information, achieved by structural and functional changes in neurons, enhancing synaptic transmission. This strengthens connections between neurons, making memories lasting.

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    Hippocampus

    A key area in the cerebral cortex involved in the formation of new long-term memories. Damage to this region can affect the ability to create new memories.

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    Thalamus

    A relay center for sensory information, directing it to the appropriate areas of the cerebral cortex for interpretation. It is essentially a 'traffic director' for sensory inputs.

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    Hypothalamus

    A vital control center for many basic functions including body temperature, hunger, thirst, and sleep-wake cycles. It plays a key role in maintaining homeostasis.

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    Amygdala

    A central structure in the limbic system, crucial for processing emotions like fear and anger. It plays a critical role in emotional learning and memory.

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    Cingulate Gyrus

    A part of the limbic system involved in processing emotions and linking them to memories. It contributes to emotional awareness and response.

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    RAS (Reticular Activating System)

    A network within the brainstem responsible for maintaining consciousness and alertness. It filters out repetitive and weak stimuli, focusing attention on important information.

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    Midbrain

    A region of the brainstem connecting the forebrain and hindbrain. It houses structures involved in vision, hearing, motor control, and sleep-wake cycles.

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    Cerebellum

    Responsible for coordinating muscle movements, balance, and posture. It receives information from proprioceptors and the visual system to fine-tune motor control.

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    Filum Terminale

    A fibrous band extending from the spinal cord to the coccyx, offering support and protection to the distal spinal cord against various forces.

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    Dorsal Root

    Part of a spinal nerve connecting to the spinal cord, carrying sensory information from the body to the brain.

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    Ventral Root

    Part of a spinal nerve connecting to the spinal cord, carrying motor commands from the brain to the body.

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    Dorsal Ramus

    A branch of a spinal nerve supplying the posterior (back) part of the trunk.

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    Ventral Ramus

    A branch of a spinal nerve supplying the rest of the trunk and limbs.

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    Meningeal Branch

    A spinal nerve branch re-entering the spinal cord to supply the meninges and blood vessels within the central nervous system.

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    Cervical Plexus

    A network of nerves in the neck formed by the ventral rami of the first four cervical nerves, supplying muscles and skin in the neck.

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    Phrenic Nerve

    A nerve from the cervical plexus that controls the diaphragm, crucial for breathing.

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    Brachial Plexus

    A complex network of nerves in the shoulder area formed by the ventral rami of lower cervical and upper thoracic nerves, supplying the upper limb.

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    Musculocutaneous Nerve

    A branch of the brachial plexus supplying muscles on the front of the forearm and skin of the forearm.

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    Axillary Nerve

    A branch of the brachial plexus supplying the shoulder area (superior, lateral, and posterior regions).

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    Median Nerve

    A branch of the brachial plexus supplying muscles and skin of the forearm and hand.

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    Ulnar Nerve

    A branch of the brachial plexus supplying muscles and skin on the little finger side of the hand.

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    Radial Nerve

    A branch of the brachial plexus supplying muscles on the back of the arm and skin of the forearm and hand.

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    Lumbar Plexus

    A network of nerves arising from the lumbar region, supplying the thigh, abdominal wall, and psoas muscle.

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    What is the photic sneeze reflex?

    A fascinating response where bright light triggers a sneeze. It affects roughly 18-25% of people due to a potential malfunction in nerve signals related to the trigeminal nerve.

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    What's the role of the trigeminal nerve in the photic sneeze reflex?

    The trigeminal nerve, responsible for various facial sensations, gets triggered by overstimulation of the optic nerve. This ultimately leads to the sneeze.

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    What is a yawn?

    Yawning is a reflex involving a deep inhale and exhale, often associated with tiredness or lack of stimulation. It's thought to increase alertness but the exact cause remains unclear.

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    What is a cerebrovascular accident (stroke)?

    A stroke happens when blood flow to the brain is blocked, leading to the death of brain tissue.

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    What are Transient Ischemic Attacks (TIAs)?

    TIAs are brief episodes of temporary brain ischemia (restricted blood flow). Unlike a stroke, the effects are reversible.

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    What is Alzheimer's disease?

    Alzheimer's is a neurodegenerative disease characterized by progressive loss of higher brain function. It's caused by neuronal loss and atrophy.

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    What is Huntington's disease?

    Huntington's is a genetic disorder. It's caused by degeneration of specific brain cells, resulting in jerky movements, cognitive decline, and behavioral changes.

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    What is flaccid paralysis?

    Flaccid paralysis is a loss of muscle function due to severe damage to the ventral root or anterior horn cells of the spinal cord.

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    Study Notes

    Nervous System 2, Unit 4, Lecture 10

    • This lecture covers the basic pattern of the central nervous system (CNS), including brain and spinal cord embryology
    • The brain has four main regions: cerebrum, diencephalon (forebrain), brainstem, and cerebellum
    • The brain is responsible for conscious experiences and homeostasis regulation
    • The spinal cord is a single structure that coordinates reflexes and integrates sensory and motor pathways
    • The cerebrum forms the majority of the brain's mass and is folded and wrinkled
    • The outer surface of the cerebrum is called the cerebral cortex, which is 2-5mm thick and contains ~75% of neural cell bodies
    • Beneath the cortex is white matter that contains bundled myelinated nerve fibers
    • The corpus callosum is a white matter pathway connecting the two cerebral hemispheres
    • The cerebrum is made up of gyri (ridges), sulci (grooves), and fissures (deep grooves), and these areas form lobes (frontal, parietal, occipital, temporal, and insula)
    • The frontal lobe controls voluntary movements, expressive language, and higher-level executive functions
    • The parietal lobe processes somatosensory sensations, including taste, hearing, sight, touch, smell, pressure, pain, temperature, vibration, and position.
    • The temporal lobe includes primary auditory sensation, and the role in the limbic system (memory)
    • The occipital lobe is responsible for visual perception/processing
    • The insula is a deep area to the lateral fissure
    • The cerebral cortex has different functional areas: sensory, motor, and association areas.
    • The cerebral cortex also contains functional groups of deep nuclei, called basal nuclei
    • Basal nuclei are used in cognitive processing and also in planning movements
    • Basal forebrain is important in learning and memory
    • Limbic cortex is a part of limbic system involved in emotion, memory, and behavior
    • Motor areas in the brain control movements
    • Primary motor areas are located in the frontal lobe and contain pyramidal cells sending impulses through the brain stem to spinal cord
    • Reticulospinal and rubrospinal tracts control balance and posture
    • Broca's area coordinates muscular actions of mouth, tongue, and larynx which enables speech
    • Frontal eye field controls eye and eyelid movements
    • Wernicke's area is the language area used in comprehension of speech and written language
    • Sensory areas interpret impulses from sensory receptors producing feelings or sensations
    • Sensory sensations like temperature, touch, pressure, and pain are located in the anterior portion of the parietal lobe
    • Vision is on posterior part of occipital lobes, and hearing on the superior posterior portions of the temporal lobe
    • Taste is near the bases of the central sulci along the lateral sulci
    • Smell arises from deep centers in the cerebrum
    • Sensory fibers cross over in the spinal cord.
    • Sensory areas involved in vision receive impulses from both eyes. Sensory areas involved in hearing receive impulses from both ears.
    • Association areas connect with each other and other brain structures.
    • Association areas analyze and interpret sensory experiences, and provide memory, reasoning, verbalization, judgment, and emotions
    • Several parts of the brain stem are part of the central nervous system (CNS): midbrain, pons, and medulla oblongata
    • The midbrain is between the diencephalon and pons.
    • The midbrain contains the cerebral peduncles and the cerebral aqueduct.
    • The midbrain has many nuclei.
    • Nuclei that control cranial nerves III (oculomotor) and IV (trochlear) are located in the midbrain
    • The midbrain also contains corpora quadrigemina, including superior and inferior colliculi
    • The midbrain also has substantia nigra and red nucleus
    • The pons is a bulging brainstem region between the midbrain and the medulla oblongata, and part of the anterior wall of the fourth ventricle
    • The pons connects the higher centers to the spinal cord and relays impulses between the motor cortex and the cerebellum
    • The pons has three cranial nerve origins: V (Trigeminal), VI (Abducens), and VII (Facial)
    • The pons contains the reticular formation nuclei
    • The reticular formation is a diffuse network of nuclei and fibers within the brain stem that plays a vital role in many functions, such as consciousness, alertness, and regulation of autonomic functions. The reticular activating system (RAS) is a component of the reticular formation.
    • The reticular formation is involved in many functions, including consciousness, alertness, regulation of autonomic functions, and motor control
    • The medulla oblongata is the most inferior part of the brain stem.
    • It contains a choroid plexus on the ventral wall of the fourth ventricle.
    • It has two longitudinal ridges called pyramids formed by corticospinal tracts.
    • Inferior olivary nuclei are gray matter that relays sensory information.
    • Cranial nerves X, XI, and XII are associated with the medulla.
    • The medulla has a cardiovascular control center that adjusts heart rate and force of contraction.
    • The medulla has respiratory control centers to adjust the depth and rate of breathing.
    • Cerebellum located at the back of brain and is responsible for the coordination of muscle control and movement.
    • The cerebellum receives signals from proprioceptors and visual signals to inform about body condition.
    • Cerebellum is primarily responsible for muscle control.
    • The posterior cortex calculates the best way to perform movement and plays role in language and problem solving.
    • Cerebellum recognizes and predicts sequences of events.
    • The ventricles of the brain are cavities that produce CSF and absorb it.
    • The ventricles are four ventricles: two lateral ventricles in each cerebral hemisphere, the third ventricle in the diencephalon and the fourth ventricle where pons and medulla are located.
    • The choroid plexus creates CSF.
    • CSF fills the ventricles of the brain.
    • Hydrocephalus occurs when excess CSF builds up in the ventricles.
    • The brain is protected by bone, meninges, and cerebrospinal fluid.
    • Harmful substances are shielded from the brain by the blood-brain barrier.
    • The meninges include three connective tissue membranes: dura mater, arachnoid mater, and pia mater
    • The dura mater is the strongest meninx.
    • The arachnoid mater is the middle meninx.
    • The pia mater is the very thin meninx that adheres to the brain.
    • The falx cerebri is a strong crescent-shaped sheet that separates the cerebral hemispheres.
    • The falx cerebelli is a small sickle-shaped fold that separates the cerebellar hemispheres.
    • The tentorium cerebelli separates the occipital and temporal lobes of the cerebral hemispheres from the cerebellum.
    • Lumbar puncture (LP) or spinal tap is done to diagnose or treat certain conditions
    • The adult brain makes up 2% of body weight, but gets 12-15% of blood supply.
    • Glucose is the energy source for brain production
    • Deprivation of either oxygen or glucose can lead to brain death.
    • The blood brain barrier separates blood-borne substances from neurons by a continuous endothelium of capillary walls, a relatively thick basal lamina and by the bulbous feet of astrocytes.
    • The blood-brain barrier prevents many substances from entering the central nervous system, thus protecting against toxins or pathogens, while allowing vital nutrients to reach the brain.
    • Substances with high lipid solubility can cross the barrier via simple diffusion.
    • Water, gases (like CO2 and O2), and volatile anesthetics readily cross the blood-brain barrier.
    • The blood brain barrier uses carrier-mediated transport for substances with low lipid solubility, such as glucose and amino acids.
    • Spinal cord is composed of ascending and descending tracts.
    • Spinal cord nerves emerge along spinal cord and are mixed nerves which branch into dorsal rami and ventral rami
    • Dorsal rami innervates posterior body trunk
    • Ventral rami innervates the rest of the trunk and limbs.
    • The lumbar plexus arises from L1-L4 and innervates the hip area, abdominal wall, and psoas muscle.
    • Sciatic nerve is the largest and longest nerve in the body and innervates the buttocks and lower limbs
    • Dermatomes are areas of skin supplied by sensory nerve fibers of a particular spinal nerve

    Reflexes

    • A reflex is a rapid motor response to a stimulus
    • Reflexes can be inborn or learned.
    • Reflexes can involve peripheral nerves and the spinal cord, or higher centers in the brain
    • A reflex arc has five components: receptor, sensory neuron, integration center, motor neuron, and effector
    • Reflexes are categorized functionally as somatic (involuntary responses) or autonomic (unconscious motor reflexes)

    Specific Reflexes in Adult Humans

    • Patellar
    • Photic sneeze reflex
    • Pupillary
    • Quadriceps
    • Scratch
    • Salivation
    • Sneeze
    • Tendon
    • Triceps stretch
    • Vestibulo-ocular
    • Withdrawal
    • Yawn
    • Accommodation
    • Achilles
    • Biceps stretch
    • Brachioradialis
    • Corneal
    • Gag

    CNS Disorders & Diseases

    • Cerebrovascular accidents (strokes)
    • Transient ischemic attacks (TIAs)
    • Alzheimer's disease
    • Huntington's disease
    • Spinal cord trauma – paralysis, flaccid paralysis, spastic paralysis
    • Transection
    • Paraplegia
    • Quadriplegia
    • Poliomyelitis
    • Amyotrophic lateral sclerosis (ALS)

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    Test your knowledge on the key functions and structures of the spinal cord and brain with this quiz. Explore topics such as motor neurons, spinal nerves, and essential brain regions related to consciousness and vital functions. Perfect for students studying neuroscience or related fields.

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