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Questions and Answers
The prefrontal cortex is the primary origin of networks that facilitate higher cognitive functions and appropriate social behavior.
The prefrontal cortex is the primary origin of networks that facilitate higher cognitive functions and appropriate social behavior.
True (A)
The amygdala is directly involved in the regulation of the circadian rhythm.
The amygdala is directly involved in the regulation of the circadian rhythm.
False (B)
The solitary tract is primarily related to emotional drive.
The solitary tract is primarily related to emotional drive.
False (B)
The suprachiasmatic nucleus solely influences the sleep-wake cycles, and does not connect to the periventricular zone.
The suprachiasmatic nucleus solely influences the sleep-wake cycles, and does not connect to the periventricular zone.
The hypothalamus solely receives integrated information from second-order neurons of the solitary tract nucleus.
The hypothalamus solely receives integrated information from second-order neurons of the solitary tract nucleus.
The behavior neural column has anterior sections involved in death stimulation, and posterior sections in signaling reproduction time.
The behavior neural column has anterior sections involved in death stimulation, and posterior sections in signaling reproduction time.
The parabrachial nucleus is a component of the thalamus.
The parabrachial nucleus is a component of the thalamus.
The hypothalamus acts to maintain a constant set point for body temperature throughout the day.
The hypothalamus acts to maintain a constant set point for body temperature throughout the day.
Vasoconstriction in response to cold is a conscious, behavioral response driven by the hypothalamus.
Vasoconstriction in response to cold is a conscious, behavioral response driven by the hypothalamus.
The limbic lobe, which includes the insula and cingulate gyrus, receives direct input from the pons.
The limbic lobe, which includes the insula and cingulate gyrus, receives direct input from the pons.
The suprachiasmatic nucleus of the hypothalamus acts as an internal clock, setting the body's circadian rhythms, including temperature variations.
The suprachiasmatic nucleus of the hypothalamus acts as an internal clock, setting the body's circadian rhythms, including temperature variations.
The vegetative system consists purely of preganglionic and postganglionic neurons in the periphery, with no CNS involvement.
The vegetative system consists purely of preganglionic and postganglionic neurons in the periphery, with no CNS involvement.
Shivering, as a response to cold, is an example of a cognitive reaction controlled by the hypothalamus.
Shivering, as a response to cold, is an example of a cognitive reaction controlled by the hypothalamus.
The hypothalamic-hypophyseal axis involves neurotransmitters mixing with the systemic blood before reaching the anterior hypophysis.
The hypothalamic-hypophyseal axis involves neurotransmitters mixing with the systemic blood before reaching the anterior hypophysis.
Parvocellular neurons, located solely in the arcuate nucleus, give rise to fibers that form the tuberohypophyseal tract.
Parvocellular neurons, located solely in the arcuate nucleus, give rise to fibers that form the tuberohypophyseal tract.
The hypophysis decides when to release its hormones, acting independently of the hypothalamus.
The hypophysis decides when to release its hormones, acting independently of the hypothalamus.
The releasing hormone from the hypothalamus directly acts on the target organ, bypassing the anterior hypophysis.
The releasing hormone from the hypothalamus directly acts on the target organ, bypassing the anterior hypophysis.
In the endocrine system, the hypophysis is the primary conductor, dictating hormonal release.
In the endocrine system, the hypophysis is the primary conductor, dictating hormonal release.
Hormones are released only when there is an environmental need, not constantly or tonically.
Hormones are released only when there is an environmental need, not constantly or tonically.
The sensory domain of the vegetative system receives input from interoceptors, with afferents entering via posterior roots into the spinal cord.
The sensory domain of the vegetative system receives input from interoceptors, with afferents entering via posterior roots into the spinal cord.
Hormones primarily target one specific organ to ensure maximum effect.
Hormones primarily target one specific organ to ensure maximum effect.
The motor domain of the vegetative system controls skeletal muscle, cardiac muscle, glands, and adipose tissue.
The motor domain of the vegetative system controls skeletal muscle, cardiac muscle, glands, and adipose tissue.
The hypothalamic-hypophyseal axis is only active during times of physiological stress, not constantly.
The hypothalamic-hypophyseal axis is only active during times of physiological stress, not constantly.
A single, easily measurable parameter is always available to check the effectiveness of hormone action.
A single, easily measurable parameter is always available to check the effectiveness of hormone action.
Visceral reflexes operate solely on a simple input-sensory-efferent-output model without any influence from supraspinal organs.
Visceral reflexes operate solely on a simple input-sensory-efferent-output model without any influence from supraspinal organs.
The blood from the first capillary bed directly enters systemic circulation without intermediary steps.
The blood from the first capillary bed directly enters systemic circulation without intermediary steps.
During intense physical exercise, the increase in heart rate and blood flow to muscles is solely due to the decreased levels of CO2 in the blood resulting from inadequate ventilation.
During intense physical exercise, the increase in heart rate and blood flow to muscles is solely due to the decreased levels of CO2 in the blood resulting from inadequate ventilation.
In stressed conditions, the vegetative system shifts its balance significantly towards the parasympathetic nervous system.
In stressed conditions, the vegetative system shifts its balance significantly towards the parasympathetic nervous system.
The hypothalamic region is primarily responsible for the coordination of activity between the vegetative system and the endocrine system.
The hypothalamic region is primarily responsible for the coordination of activity between the vegetative system and the endocrine system.
Neuroendocrine reflexes are a type of visceral reflex which inhibits hormone release in response to a specific stimulus.
Neuroendocrine reflexes are a type of visceral reflex which inhibits hormone release in response to a specific stimulus.
Preganglionic neurons, acting as the lower motoneurons of the vegetative system, receive inputs exclusively from interoceptors.
Preganglionic neurons, acting as the lower motoneurons of the vegetative system, receive inputs exclusively from interoceptors.
Central autonomic regulatory systems only impact visceral functions, and they do not affect neuroendocrine outflow.
Central autonomic regulatory systems only impact visceral functions, and they do not affect neuroendocrine outflow.
The coordination of appropriate autonomic responses is facilitated solely by sensory information without any adjustments based on ongoing needs.
The coordination of appropriate autonomic responses is facilitated solely by sensory information without any adjustments based on ongoing needs.
The forebrain is comprised of the amygdala, limbic cortex, and cerebellum.
The forebrain is comprised of the amygdala, limbic cortex, and cerebellum.
The spinal cord's autonomic reflexes are triggered only by external stimuli.
The spinal cord's autonomic reflexes are triggered only by external stimuli.
The limbic system of the cortex can only act on the brainstem and hypothalamus and cannot generate behavioral responses.
The limbic system of the cortex can only act on the brainstem and hypothalamus and cannot generate behavioral responses.
The descending system from the hypothalamus involves hypothalamic-spinal and corticospinal pathways.
The descending system from the hypothalamus involves hypothalamic-spinal and corticospinal pathways.
The primary role of the hypothalamus is to control cognitive behaviors.
The primary role of the hypothalamus is to control cognitive behaviors.
Sensory information from the heart, lungs, and GU tract is sent directly to the spinal cord.
Sensory information from the heart, lungs, and GU tract is sent directly to the spinal cord.
The telencephalon sends information to the lower brain stem to regulate the CV, respiratory, and GU systems.
The telencephalon sends information to the lower brain stem to regulate the CV, respiratory, and GU systems.
Homeostatic regulation of respiration is primarily controlled by the upper brainstem.
Homeostatic regulation of respiration is primarily controlled by the upper brainstem.
The cardiovascular network sends signals only to sympathetic premotor or preganglionic neurons.
The cardiovascular network sends signals only to sympathetic premotor or preganglionic neurons.
The two respiratory networks signal only the respiratory premotor neurons.
The two respiratory networks signal only the respiratory premotor neurons.
Flashcards
Pons functions
Pons functions
Contains nuclei like parabrachial, raphe, reticular, and periaqueductal gray, involved in various functions.
Hypothalamus input sources
Hypothalamus input sources
Receives information from the solitary tract nucleus, third-order neurons, and raw data from the spinal cord.
Set point concept
Set point concept
Hypothalamus compares desired vs. actual values for physiological parameters and modulates hormone release.
Hypothalamus responses to cold
Hypothalamus responses to cold
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Suprachiasmatic nucleus role
Suprachiasmatic nucleus role
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CNS and vegetative system
CNS and vegetative system
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Thalamus pathways
Thalamus pathways
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Hypothalamus functionality
Hypothalamus functionality
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Hypothalamic-Hypophyseal Axis
Hypothalamic-Hypophyseal Axis
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Parvocellular Neurons
Parvocellular Neurons
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Tuberohypophyseal Tract
Tuberohypophyseal Tract
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Anterior Hypophysis
Anterior Hypophysis
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Endocrine Glands
Endocrine Glands
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Hormonal Feedback
Hormonal Feedback
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Releasing Hormones
Releasing Hormones
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Endocrine System Control
Endocrine System Control
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Constant Hormone Release
Constant Hormone Release
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Tissue Trophism
Tissue Trophism
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Prefrontal Cortex
Prefrontal Cortex
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Amygdala
Amygdala
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Suprachiasmatic Nucleus
Suprachiasmatic Nucleus
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Autonomic System Output
Autonomic System Output
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Behavioral Column
Behavioral Column
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Autonomic Nervous System (ANS)
Autonomic Nervous System (ANS)
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Visceral Reflexes
Visceral Reflexes
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Supraspinal Structures
Supraspinal Structures
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Preganglionic Neurons
Preganglionic Neurons
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Interceptors
Interceptors
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Sympathetic System
Sympathetic System
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Parasympathetic System
Parasympathetic System
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Neuroendocrine Reflexes
Neuroendocrine Reflexes
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Central Autonomic Regulatory Systems
Central Autonomic Regulatory Systems
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Coherence of Systems
Coherence of Systems
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Forebrain
Forebrain
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Hypothalamus
Hypothalamus
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Brainstem
Brainstem
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Spinal Cord
Spinal Cord
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Autonomic reflexes
Autonomic reflexes
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Limbic System
Limbic System
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Interneurons
Interneurons
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Ponto-medullary networks
Ponto-medullary networks
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Homeostatic regulation
Homeostatic regulation
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Study Notes
Autonomic Actions and Motivational States
- The vegetative system, parallel to the somatic system, has sensory and motor domains.
- Sensory input comes from interoceptors. Afferents enter the spinal cord via posterior roots.
- Motor output involves sympathetic and parasympathetic systems acting on smooth muscle, cardiac muscle, and glands.
- Visceral reflexes are complex, controlled by supraspinous organs (like the hypothalamus).
- A coherence exists between vegetative and endocrine activity, often through the hypothalamus.
- Visceral reflexes have slow and rapid responses to stimuli from interoceptors.
- Preganglionic neurons are the lower motor neurons of the autonomic nervous system.
- Supraspinous structures coordinate autonomic responses by transmitting sensory information through central autonomic regulatory systems.
- These systems coordinate actions affecting visceral functions and neuroendocrine outflow.
Hypothalamic Hierarchy
- The forebrain, composed of the amygdala and limbic cortex, and the hypothalamus form a hierarchy.
- Amygdala and limbic cortex: drive cognitive and emotional behavior.
- Hypothalamus: central for drive states (motivational) and homeostasis.
- Brainstem centers control cardiac, respiratory, and gastrointestinal functions.
- Spinal cord mediates autonomic reflexes initiated by sensory inputs.
- Two pathways relate to sensory stimulus and autonomic response:
- Pathway 1: spinal interneurons in the lateral horn (lamina VII)
- Pathway 2: hypothalamus, influencing brainstem with descending (hypothalamic-spinal and reticulospinal) systems that act on preganglionic neurons
- Pathway 3: activating the brainstem and hypothalamus while also activating the limbic system of the cortex. The cortex can either act on the brainstem/hypothalamus or directly generate behavioral responses.
Hypothalamic Nuclei and Structures
- The hypothalamus is divided into anterior, middle, and posterior regions; each with specific nuclei.
- Anterior region: preoptic nucleus, supraoptic nucleus, paraventricular nucleus, and anterior nuclei; suprachiasmatic nucleus.
- Middle region: dorsomedial nucleus, ventromedial nucleus.
- Posterior region: mamillary nucleus.
- Hypothalamus is also divided into three mediolaterally distributed zones: periventricular zone, medial zone, and lateral zone.
- The periventricular zone contains important autonomic and endocrine nuclei.
- The medial zone contains the suprachiasmatic nucleus (SCN), the biological clock.
- The lateral zone includes hypocretin/orexin producing nuclei, important for hunger and cardiovascular control.
Hypothalamic Functions and Regulation
- The hypothalamus regulates homeostasis (internal balance) via coordinated actions on endocrine and autonomic systems.
- Homeostatic regulation is reflected in the lower brain stem anatomy and physiology.
- The hypothalamus connects with other brain regions concerning emotional experience, motivation, sleep/wake cycles, and food intake.
- The hypothalamus receives sensory information by several pathways. These include direct and indirect inputs, as well as hormonal signals from organs.
Hormone Release and Hypophysis
- Endocrine portions of the hypothalamus communicate mainly with the pituitary gland.
- The neurohypophysis originates from supraoptic and magnocellular nuclei. It is not composed of epithelial tissue, but from axons of neurons.
- Neurosecretory cells synthesize and release hormones like vasopressin and oxytocin.
- The hormones are released into extracellular space of median eminence, infundibular stalk, and posterior pituitary, then passing into general circulation.
- Oxytocin has target cells in uterus and mammary glands, stimulating contractions and milk ejection.
- Antidiuretic hormone (ADH) regulates blood osmolarity via kidney function and blood vessel constriction.
- Hypothalamic nuclei (arcuate, paraventricular) release various releasing/inhibiting hormones that control hormone release from the anterior pituitary (adenohypophysis).
Hypothalamic-Hypophyseal Axis
- Unlike posterior pituitary, the anterior pituitary does not receive direct hypothalamic axonal projections.
- The hypothalamus communicates with the anterior pituitary via specialized portal vessels forming the hypothalamic-hypophyseal portal system
- Releasing/inhibiting hormones are transported to the anterior pituitary without dilution, regulating glandular hormone release.
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