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Questions and Answers
Initiation of the action potential usually occurs ______ of the neuron.
Initiation of the action potential usually occurs ______ of the neuron.
- on the dendrites
- in the cell body
- at the axon initial segment (correct)
- on the axon
Which statement about an animal's nervous system is true?
Which statement about an animal's nervous system is true?
- Signal transmission rate is relatively slow.
- Neurons form highly discrete lines of communication. (correct)
- Action potential signals degrade over distance.
- Neurotransmitter is released throughout the body via the blood.
For a hormone to elicit a specific response from a cell, the cell must possess
For a hormone to elicit a specific response from a cell, the cell must possess
- a synapse
- a cell body
- dendrites specific to the hormone
- receptor proteins specific to the hormone (correct)
Which statement about the startle response of the cockroach is true?
Which statement about the startle response of the cockroach is true?
At the metathoracic ganglion, the interneurons synaptically inhibit leg motor neurons.
At the metathoracic ganglion, the interneurons synaptically inhibit leg motor neurons.
Which glial cells are found in the peripheral nervous system?
Which glial cells are found in the peripheral nervous system?
Which statement about glial cells is true?
Which statement about glial cells is true?
The separation of positive and negative charges constitutes
The separation of positive and negative charges constitutes
Which statement about membrane capacitance is true?
Which statement about membrane capacitance is true?
What is occurring at the membrane?
What is occurring at the membrane?
In the lower panel, the difference between the dashed line and the solid red line is due to
In the lower panel, the difference between the dashed line and the solid red line is due to
In the figure, the ______ decreases with distance.
In the figure, the ______ decreases with distance.
Which statement offers the best explanation for the difference between the middle panel and the lower panel?
Which statement offers the best explanation for the difference between the middle panel and the lower panel?
The properties shown in the figure can be measured in
The properties shown in the figure can be measured in
Which variable does not contribute to the passive electrical properties of a cell?
Which variable does not contribute to the passive electrical properties of a cell?
The figure shows that the membrane potential results from
The figure shows that the membrane potential results from
In the figure, ______ in the center of the cell.
In the figure, ______ in the center of the cell.
Which characteristic is not a factor in the Nernst Equation?
Which characteristic is not a factor in the Nernst Equation?
In a cell, the difference in ion concentration between the intracellular and extracellular fluids results from
In a cell, the difference in ion concentration between the intracellular and extracellular fluids results from
According to the Nernst equation, which change will depolarize Vm, the membrane potential?
According to the Nernst equation, which change will depolarize Vm, the membrane potential?
Which statement regarding the ions in intracellular and extracellular fluids in a standard animal cell is true?
Which statement regarding the ions in intracellular and extracellular fluids in a standard animal cell is true?
According to the Goldman equation, the contribution of each ion to the membrane potential depends most on
According to the Goldman equation, the contribution of each ion to the membrane potential depends most on
Which structure is most responsible for the all-or-none property of the action potential?
Which structure is most responsible for the all-or-none property of the action potential?
Which arrow best represents the point where permeability to sodium is the highest?
Which arrow best represents the point where permeability to sodium is the highest?
Which arrow best represents the point where the voltage-gated sodium channels are inactivated?
Which arrow best represents the point where the voltage-gated sodium channels are inactivated?
______ channels are responsible for the undershoot at point D of the figure.
______ channels are responsible for the undershoot at point D of the figure.
What occurs when the membrane is clamped at -100 mV?
What occurs when the membrane is clamped at -100 mV?
How many separate current pulses cause the membrane potential to reach the threshold?
How many separate current pulses cause the membrane potential to reach the threshold?
What would likely occur if stimulus 3 and 6 were performed simultaneously?
What would likely occur if stimulus 3 and 6 were performed simultaneously?
If stimulating current pulse 9 (not shown) was both stronger and longer than stimulating current pulse 8, then
If stimulating current pulse 9 (not shown) was both stronger and longer than stimulating current pulse 8, then
For an axon at resting membrane potential, the K⁺ leak channel is ______ the voltage-gated Na⁺ channel is ______ and the voltage-gated K+ channel is ______.
For an axon at resting membrane potential, the K⁺ leak channel is ______ the voltage-gated Na⁺ channel is ______ and the voltage-gated K+ channel is ______.
During the falling phase of an action potential, the K+ leak channel on the axon is ______, the voltage-gated Na⁺ channel is ______, and the voltage-gated K+ channel is ______
During the falling phase of an action potential, the K+ leak channel on the axon is ______, the voltage-gated Na⁺ channel is ______, and the voltage-gated K+ channel is ______
Which technique was used to collect the data in the bottom panel?
Which technique was used to collect the data in the bottom panel?
On the figure, I represents ______ currents through voltage-gated ______ channels.
On the figure, I represents ______ currents through voltage-gated ______ channels.
Why do the channels at II on the figure stay open longer than those at I?
Why do the channels at II on the figure stay open longer than those at I?
Which technique was used to collect the data shown in the figure?
Which technique was used to collect the data shown in the figure?
The treatment difference between the membranes shown in the graphs is that the membrane on the left is being ______ while the membrane on the right is being ______.
The treatment difference between the membranes shown in the graphs is that the membrane on the left is being ______ while the membrane on the right is being ______.
How would the trace on the right look if the neuron was soaking in TEA?
How would the trace on the right look if the neuron was soaking in TEA?
Which statement about a voltage clamp of a neuron at 0 mV is true?
Which statement about a voltage clamp of a neuron at 0 mV is true?
Which statement regarding the structure of the voltage-gated Na⁺ channels is false?
Which statement regarding the structure of the voltage-gated Na⁺ channels is false?
A spiking neuron and a nonspiking neuron share which characteristic?
A spiking neuron and a nonspiking neuron share which characteristic?
How do nonspiking neurons function even though their depolarization signal significantly degrades with distance?
How do nonspiking neurons function even though their depolarization signal significantly degrades with distance?
The figure depicts a
The figure depicts a
What is the best explanation for the plateau shown in the figure?
What is the best explanation for the plateau shown in the figure?
Which statement about ion permeability as shown in the figure is true?
Which statement about ion permeability as shown in the figure is true?
The absolute refractory period of the action potential is best explained by
The absolute refractory period of the action potential is best explained by
Which statement about a local circuit in an axon is false?
Which statement about a local circuit in an axon is false?
______ prevents bidirectional propagation of action potentials.
______ prevents bidirectional propagation of action potentials.
Conduction velocity shows ______ axon diameter.
Conduction velocity shows ______ axon diameter.
Considering neurons in living systems, which variable affects conduction velocity the most?
Considering neurons in living systems, which variable affects conduction velocity the most?
Myelination by Schwann cells increases the velocity of action potential propagation by
Myelination by Schwann cells increases the velocity of action potential propagation by
Compare and contrast nervous systems and endocrine systems.
Compare and contrast nervous systems and endocrine systems.
Describe the startle response in the cockroach.
Describe the startle response in the cockroach.
What are glial cells and how do they aid in the function of the nervous system?
What are glial cells and how do they aid in the function of the nervous system?
Compare and contrast current and voltage with respect to the cell membrane.
Compare and contrast current and voltage with respect to the cell membrane.
Since the bulk solutions that make up the intracellular and extracellular fluids maintain charge neutrality, how does the cell produce membrane potentials?
Since the bulk solutions that make up the intracellular and extracellular fluids maintain charge neutrality, how does the cell produce membrane potentials?
Explain in mechanistic terms how the action potential is an all-or-none phenomenon.
Explain in mechanistic terms how the action potential is an all-or-none phenomenon.
Compare and contrast the techniques of patch clamping and voltage clamping.
Compare and contrast the techniques of patch clamping and voltage clamping.
What are the similarities and differences among the channels in the voltage-gated channel superfamily?
What are the similarities and differences among the channels in the voltage-gated channel superfamily?
Explain in mechanistic terms why the action potential can travel a great distance along an axon without degrading.
Explain in mechanistic terms why the action potential can travel a great distance along an axon without degrading.
Describe the significance of myelination.
Describe the significance of myelination.
The neuron converts an electrical signal to a chemical signal in the
The neuron converts an electrical signal to a chemical signal in the
Neurons that relay sensory signals to integrative centers of the CNS are called
Neurons that relay sensory signals to integrative centers of the CNS are called
Which glial cells function as metabolic intermediaries between capillaries and neurons?
Which glial cells function as metabolic intermediaries between capillaries and neurons?
Which term best describes the movement of ions across a membrane?
Which term best describes the movement of ions across a membrane?
A decrease in the absolute value of the membrane potential toward zero is called
A decrease in the absolute value of the membrane potential toward zero is called
Which of the following actively contributes to the cell’s membrane potential?
Which of the following actively contributes to the cell’s membrane potential?
The time constant (τ) depends on the _______ of the membrane.
The time constant (τ) depends on the _______ of the membrane.
Flashcards
Action Potential Initiation
Action Potential Initiation
Typically occurs at the axon initial segment of a neuron and not in the cell body or dendrites.
Nervous System Communication
Nervous System Communication
Signal transmission in nervous systems is fast and involves highly specific lines of communication, unlike the more general communication of the endocrine system.
Hormone Receptor Binding
Hormone Receptor Binding
Cells respond to hormones if they have specific receptor proteins that match the hormone's structure.
Cockroach Startle Response
Cockroach Startle Response
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Peripheral Glial Cells
Peripheral Glial Cells
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Glial Cell Function
Glial Cell Function
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Voltage
Voltage
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Membrane Capacitance
Membrane Capacitance
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Membrane Depolarization
Membrane Depolarization
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Graded Potential Decay
Graded Potential Decay
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Nernst Equation Components
Nernst Equation Components
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Membrane Potential Determinants
Membrane Potential Determinants
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Goldman Equation
Goldman Equation
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All-or-None Action Potential
All-or-None Action Potential
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Voltage-Gated Na+ Channels
Voltage-Gated Na+ Channels
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Action Potential Propagation
Action Potential Propagation
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Myelin's Effect on Conduction
Myelin's Effect on Conduction
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Absolute Refractory Period
Absolute Refractory Period
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Cardiac Action Potential Plateau
Cardiac Action Potential Plateau
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Study Notes
Test Bank Questions - Chapter 12: Neurons
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Action Potential Initiation: The action potential typically begins at the axon initial segment of a neuron.
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Nervous System Function: The nervous system's communication is routed through discrete neural pathways, not via the bloodstream. Signal transmission is relatively slow compared to other systems.
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Hormone Response: For a hormone to trigger a specific cellular response, the cell must possess appropriate receptor proteins.
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Cockroach Startle Response: The startle response in cockroaches involves sensory hairs triggering nerve impulses that lead to the spinal cord.
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Peripheral Nervous System Glial Cells: Schwann cells are a specific type of glial cell found in the peripheral nervous system.
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Glial Cell Function: Glial cells provide metabolic support to neurons.
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Membrane Potential Components: Membrane potentials are due to differences in charge separation (voltage).
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Membrane Capacitance: Membrane capacitance is the ability of a membrane to store charge; it is in series with membrane resistance.
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Graded Potential: A graded potential (in a figure) is a change in membrane voltage that is proportional to the change in the stimulus strength. Depolarization is an increase in membrane potential; hyperpolarization is a decrease.
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Action Potential: An action potential is a rapid and substantial change in membrane voltage; it is characterized by a rising phase (depolarization); a falling phase (repolarization); and an undershoot (hyperpolarization).
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Sodium and Potassium Channels: Various channels (voltage-gated sodium, voltage-gated potassium) influence action potential.
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Passive Electrical Properties: Membrane resistance and capacitance affect the passive electrical properties of a cell.
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Cell Membrane Potential: The cellular membrane potential is influenced by the concentration gradients of various ions (like sodium, potassium, and chloride) across the cell.
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Nernst Equation: This equation determines the equilibrium potential for a given ion, considering factors like ion concentrations and electrical charge.
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Membrane Potential Factors: A number of factors such as membrane resistance and capacitance determines the passive electrical properties of the cell.
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All-or-None Principle: Neurons exhibit an all-or-none response in their action potentials depending on whether the voltage at the triggering zone reaches the threshold value. This is a critical property of action potentials in neurons.
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Action Potential Phases: Voltage-gated sodium channels open during the rising phase and then become inactivated; voltage-gated potassium channels open during the falling phase.
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Refractory Period: The absolute refractory period is when sodium channels are inactivated, preventing further action potentials.
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Sodium Channel Inactivation: Sodium channels inactivate during an action potential, leading to the falling phase of the action potential.
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Potassium Channels and Undershoot: K+ channel opening and subsequent K+ efflux produce the undershoot phase (hyperpolarization) after an action potential.
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Action Potential Conduction Velocity: Factors such as axon diameter and myelination significantly affect conduction velocity of the action potential.
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Myelination: Myelination increases the speed of action potential propagation by increasing the resistance and decreasing capacitance of the axon.
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Neurotransmitter Release: Neurotransmitter release occurs at the synapse as a result of an action potential triggering the release from the axon terminal.
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Neural and Endocrine Communication: Nervous systems exhibit much faster and more precise responses compared to endocrine systems.
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Glial Cells: Glial cells support neurons with metabolic intermediaries between capillaries and neurons, maintaining a conducive environment for neural activity.
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Current and Voltage: Electric current is the net movement of charge; voltage is charge separation.
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Action Potential Mechanism: Ion flow (e.g., sodium influx, potassium efflux) drives the action potential.
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Action Potential Characteristics: Action potentials are rapid, large changes in membrane potential that are responsible for signal transmission in neurons.
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Pacemaker Cells: Pacemaker cells self-generate action potentials that can be regulated.
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Action Potential Measurement Techniques: Specialized techniques, such as the voltage clamp or patch-clamp method, allow for understanding action potential characteristics.
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Local Circuit: The local circuit involves current flow within the neuron to propagate the action potential, facilitating rapid and effective transmission.
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