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Questions and Answers
Which part of a neuron is responsible for receiving signals from other neurons?
Which part of a neuron is responsible for receiving signals from other neurons?
What is the function of the myelin sheath?
What is the function of the myelin sheath?
What is the gap between neurons called?
What is the gap between neurons called?
What is the role of neurotransmitters in the transmission of signals between neurons?
What is the role of neurotransmitters in the transmission of signals between neurons?
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Which of the following is NOT part of a neuron?
Which of the following is NOT part of a neuron?
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Which of these is directly related to the evolutionary theories of Darwin and Wallace?
Which of these is directly related to the evolutionary theories of Darwin and Wallace?
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Which theory suggests that specific areas of the brain are responsible for different behaviors?
Which theory suggests that specific areas of the brain are responsible for different behaviors?
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What was Descartes's contribution to the understanding of the mind and body?
What was Descartes's contribution to the understanding of the mind and body?
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Which of the following is NOT a function of the brain?
Which of the following is NOT a function of the brain?
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Which of these is included in the Central Nervous System (CNS)?
Which of these is included in the Central Nervous System (CNS)?
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What is the primary role of the Peripheral Nervous System (PNS)?
What is the primary role of the Peripheral Nervous System (PNS)?
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Which of these is NOT a function of the Cerebral Cortex?
Which of these is NOT a function of the Cerebral Cortex?
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What is the main idea presented about the brain's role in the body?
What is the main idea presented about the brain's role in the body?
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Which of these theories suggests that behavior can be fully understood by studying the nervous system?
Which of these theories suggests that behavior can be fully understood by studying the nervous system?
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Which of these is NOT a part of the modern theories about behavior?
Which of these is NOT a part of the modern theories about behavior?
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Which of the following statements is TRUE about the proportion of glial cells in the human brain?
Which of the following statements is TRUE about the proportion of glial cells in the human brain?
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What is the primary function of a sensory neuron?
What is the primary function of a sensory neuron?
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Which of the following characteristics is NOT shared by both motor and sensory neurons?
Which of the following characteristics is NOT shared by both motor and sensory neurons?
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Which area of the brain has the highest ratio of glial cells to neurons?
Which area of the brain has the highest ratio of glial cells to neurons?
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What is a primary function of glial cells?
What is a primary function of glial cells?
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What is the primary function of the endoplasmic reticulum in a neuron?
What is the primary function of the endoplasmic reticulum in a neuron?
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According to the Neuron Theory, what is the fundamental unit of the nervous system?
According to the Neuron Theory, what is the fundamental unit of the nervous system?
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Which of the following structures is responsible for performing metabolic activities and providing energy for the cell?
Which of the following structures is responsible for performing metabolic activities and providing energy for the cell?
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What is the main difference between the views of Santiago Ramón y Cajal and Camillo Golgi regarding the nervous system?
What is the main difference between the views of Santiago Ramón y Cajal and Camillo Golgi regarding the nervous system?
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Which of these is NOT a structural component of a neuron as described in the given text?
Which of these is NOT a structural component of a neuron as described in the given text?
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What is the significance of the membrane surrounding a neuron?
What is the significance of the membrane surrounding a neuron?
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Which cellular structure is primarily responsible for synthesizing new protein molecules in a neuron?
Which cellular structure is primarily responsible for synthesizing new protein molecules in a neuron?
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What is the primary function of the nucleus within a neuron?
What is the primary function of the nucleus within a neuron?
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What is the purpose of the myelin sheath?
What is the purpose of the myelin sheath?
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Which part of the neuron receives signals from other neurons?
Which part of the neuron receives signals from other neurons?
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What is the main function of the brain stem?
What is the main function of the brain stem?
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What happens when a signal reaches the end of the axon?
What happens when a signal reaches the end of the axon?
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What is the role of the cerebellum in the nervous system?
What is the role of the cerebellum in the nervous system?
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What is the function of the callosum?
What is the function of the callosum?
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How do neurons communicate with each other?
How do neurons communicate with each other?
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What is the main focus of Biological Psychology, as described in the provided excerpt?
What is the main focus of Biological Psychology, as described in the provided excerpt?
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What is the key difference between Biological Psychology and traditional psychology, as highlighted in the excerpt?
What is the key difference between Biological Psychology and traditional psychology, as highlighted in the excerpt?
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What is the main concept addressed by the 'Mind-Body Problem,' as presented in the excerpt?
What is the main concept addressed by the 'Mind-Body Problem,' as presented in the excerpt?
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Why is the myth of Psyche and Cupid mentioned in the context of the Mind-Body Problem?
Why is the myth of Psyche and Cupid mentioned in the context of the Mind-Body Problem?
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What is the 'mentalism' theory as discussed in the excerpt?
What is the 'mentalism' theory as discussed in the excerpt?
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What is Aristotle's theory regarding the relationship between the mind and the body?
What is Aristotle's theory regarding the relationship between the mind and the body?
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What is the significance of the statement "every observable action and higher cognitive function has an observable underlying biological cause" in the context of Biological Psychology?
What is the significance of the statement "every observable action and higher cognitive function has an observable underlying biological cause" in the context of Biological Psychology?
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What is the main takeaway from the "Mind-Body Problem" as presented in the excerpt?
What is the main takeaway from the "Mind-Body Problem" as presented in the excerpt?
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Flashcards
Biological Psychology
Biological Psychology
Study of physiological, evolutionary, and developmental mechanisms of behavior.
Mind-Body Problem
Mind-Body Problem
The question of how a non-material mind interacts with the material body.
Mentalism
Mentalism
The belief that the psyche/mind is responsible for behavior and emotions.
Psyche
Psyche
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Aristotle's view on movement
Aristotle's view on movement
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Cognition
Cognition
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Behavior
Behavior
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Evolutionary mechanisms
Evolutionary mechanisms
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Corpus Callosum
Corpus Callosum
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Brain Stem
Brain Stem
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Cerebellum
Cerebellum
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Neurones
Neurones
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Dendrites
Dendrites
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Axon
Axon
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Myelin Sheath
Myelin Sheath
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Electrochemical Signals
Electrochemical Signals
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Motor Neuron
Motor Neuron
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Sensory Neuron
Sensory Neuron
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Glial Cells
Glial Cells
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Neuron to Glia Ratio
Neuron to Glia Ratio
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Variation of Glial Cells
Variation of Glial Cells
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Cell Body
Cell Body
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Synapse
Synapse
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Neurotransmitter
Neurotransmitter
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Dualism
Dualism
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Pineal Gland
Pineal Gland
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Materialism
Materialism
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Localization of Function
Localization of Function
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Central Nervous System (CNS)
Central Nervous System (CNS)
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Peripheral Nervous System (PNS)
Peripheral Nervous System (PNS)
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Cerebral Cortex
Cerebral Cortex
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Functions of the Brain
Functions of the Brain
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Phrenology
Phrenology
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Santiago Ramón y Cajal
Santiago Ramón y Cajal
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Neuron Theory
Neuron Theory
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Neuron structure
Neuron structure
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Cell Membrane
Cell Membrane
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Nucleus
Nucleus
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Mitochondria
Mitochondria
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Ribosomes
Ribosomes
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Endoplasmic Reticulum
Endoplasmic Reticulum
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Study Notes
Biological Psychology 1: Introduction
- Course code: PSY1617
- Lecturer: Dr Massimo Pierucci
- University: University of Malta
- Required text: Kalat James W., Biological Psychology, 12th Edition, International Edition, Wadsworth, Cengage Learning.
- Further reading options include: An introduction to brain and behavior, Fundamentals of Human Neuropsychology, Neurobiology, Molecules, Cells and Systems, Principles of Neural Sciences.
Biological Psychology: Definitions
- Study of physiological, evolutionary, and developmental mechanisms of behavior and experience.
- Study of biological mechanisms of normal and abnormal behaviors (both brain and body).
- Not interested in the human mind and its functions using a "black box" perspective.
- Focuses on the hardware implementing cognition and behavior.
- Goal is to link biology to psychology by understanding the correlation between brain functions and behavior, where every observable action/cognitive function has a corresponding biological cause.
Mind-Body Problem
- Hypothesis that the mind controls behavior started around 2000 years ago with Greek-Roman mythology (Psyche and Cupid).
- Aristotle linked behavior to a person's psyche (not the brain); this view was responsible for behavior/emotions.
- Mentalism: Mind (psyche) is linked to behavior/emotions.
- The mind, a non-material entity, influences body movements.
Modern Theories
- Materialism: Behavior is explained solely by the nervous system, without needing to consider a non-material mind.
- Gall's Localization of Function: Specific brain areas control distinct behaviors or traits.
- Phrenology (Cranioscopy): Studying the skull's bumps to assess personality and mental abilities (considered pseudoscience today).
Brain and Neuron Theories
- Structure of brain with three regions: Reptilian brain (instincts and urges), Limbic brain (emotions and motivation), and the Neo-cortex (decision making).
- This is a simplified model illustrating the interconnectedness of these regions.
Nervous System
- The nervous system is divided into the central nervous system (CNS), which includes the brain and spinal cord, and the peripheral nervous system (PNS), which connects everything to the brain and spinal cord.
- The CNS is divided into the somatic and autonomic nervous systems.
- The somatic nervous system is further divided into cranial and spinal nerves.
- The autonomic nervous system comprises the sympathetic and parasympathetic divisions.
The Brain
- Interprets sensory information, monitors and regulates body functions, and is responsible for thinking, learning, memory, and emotions.
- Different brain regions have specific functions.
- The corpus callosum connects the brain's right and left hemispheres.
- Brain stem regulates heart rate, breathing, sleep cycles, and emotions.
- Cerebral cortex for planning, reasoning, language, and recognizing sounds/images/memory.
- Cerebellum coordinates , precision, and timing of movements.
Neurons
- The basic units of the nervous system; they communicate through electrical and chemical signals.
- Structures include: dendrites, cell body, axon, myelin sheath, nerve endings.
- Electrical signals travel down the axon until reaching the nerve endings.
- Neurons communicate with each other through synapses.
- Signals cross between neurons at the synapse; the signal is transmitted to another neuron across a junction called a synapse by neurotransmitters.
- Electrical impulse at the synapses: vesicles (carrying signals) fuse into the membrane; nerves end release neurotransmitter into the synaptic cleft; neurotransmitter diffuses across the cleft; receptors receive transmitters; Once enough receptors have transmitters, the signal is transmitted.
Neuromuscular Junction (NMJ)
- The point where the nervous system meets the muscles; it's where the nerve impulse causes muscle contraction.
Action Potential
- Hodgkin and Huxley's 1939 research on squid giant axons recorded for the first time the action potential and the propagation of electrical signals.
The Cells of the Nervous System
- Mental experiences depend on the activity of many separate but interconnected cells.
- Understanding these interconnected cells helps understand how the nervous system works.
Neurons and Glia
- The nervous system consists of neurons and glial cells.
- Neurons transmit electrical impulses, while glial cells insulate, support, and nourish neurons.
- The human brain has approximately 100 billion neurons.
How Many Neurons?
- Cerebral cortex (and related areas): 12-15 billion neurons.
- Spinal cord: 1 billion neurons.
- Cerebellum: 70 billion neurons
Santiago Ramón y Cajal (Pioneer of Neuroscience)
- Demonstrated that nervous system cells remain separate, not merged as previously believed .
- Described neuron theory whereby neurons are functional units.
The Structures of an Animal Cell (Part 1)
- Neurons contain the same fundamental structures as other body cells, including the membrane, nucleus, mitochondria, ribosomes, and endoplasmic reticulum.
Structures of an Animal Cell (Part 2)
- Membrane separates the inside of the cell from the outside environment.
- Nucleus contains the chromosomes.
- Mitochondria perform metabolic activities and supply energy to the cells.
Structures of an Animal Cell (Part 3)
- Ribosomes synthesize proteins.
- Endoplasmic reticulum transports newly synthesized proteins.
The Structure of a Neuron
- Similar to other cells but with a unique structural shape.
- Structural and functional unit of the nervous system.
- Polarized: receiving and sending signals.
- Complex intracellular machinery is needed to support function.
- Lasts a lifetime, doesn't undergo mitosis (except in embryonic stages).
- Requires a large amount of oxygen and glucose.
- Specialized cytoskeleton determines the shape.
Components of Neurons
- Dendrites: collect information from other neurons.
- Soma/cell body: integrates information from dendrites, processes it in the cell body, and then passes it to the axon.
- Axon: carries the processed information.
- Presynaptic terminals: release chemicals to communicate with other neurons.
Dendrites
- Branching fibers with synaptic receptors for incoming information.
- Dendritic spines increase surface area, enabling a neuron to receive more information.
Synapses/Dendritic Spines
- Number of synapses/dendritic spines change during development, sensory stimulation, and experience.
Cell Body/Soma
- Contains the nucleus, mitochondria, and ribosomes.
- Responsible for the neuron's metabolic work.
- Covered with synapses in many neurons.
Axons
- Thin fibers that transmit nerve impulses.
- May have a myelin sheath (insulation) with interruptions called nodes of Ranvier.
- Presynaptic terminals at axon ends release chemicals to communicate with other neurons.
Afferent, Efferent, and Intrinsic Neurons
- Afferent axon: brings information into a structure.
- Efferent axon: carries information away from a structure.
- Interneurons/Intrinsic neurons: dendrites and axons entirely within a single structure.
Variations Among Neurons
- Neurons vary in size, shape, and function.
- A neuron's shape determines its connections and contribution to the nervous system.
- Example: Purkinje cells in the cerebellum have extensively branching shapes.
Motor and Sensory Neurons
- Motor neuron: soma in spinal cord, receives excitation, transmits impulses to muscles.
- Sensory neuron: specialized end (sensitive to stimulation such as touch, light, sound).
The Glial Cells
- Supporting cells that insulate and nourish neurons, maintaining structural integrity.
- Examples: Oligodendrocytes (CNS), Schwann cells (PNS), Astrocytes, Microglia, Ependymal cells.
The proportion of glial cells varies across regions
- The ratio of glial cells to neurons varies; in the telencephalon, it's about 3.8 to 1, and in the cerebellum, 0.2 to 1.
Types of Glia
- Astrocytes: help synchronize axons by wrapping around presynaptic terminals, taking up chemicals, and regulating blood flow.
- Microglia: remove waste material, viruses, and fungi.
Glial Cells (Part 2)
- Oligodendrocytes (CNS)/Schwann cells (PNS): build myelin sheaths around neurons.
- Radial glia: guide neuron migration and growth.
Glial Cells (Part 3)
- Most radial glia differentiate into neurons, astrocytes, and oligodendrocytes after embryonic development concludes.
Shapes of Glial Cells
- Distinct shapes and appearances; their structure is closely linked to their functions.
Ependymal Cells
- Specialized cells in the ventricles; responsible for making CSF.
Astrocytes: Further details
- Highly branched; forms network through gap junctions
- When associated with synapse, take up and release chemicals (neurotransmitters), provide structural support, creating a framework/scaffolding for neurons, and are in contact with blood vessels.
- Form blood-brain barrier and regulate exchange of materials to maintain and support brain activities
- Increase supply of oxygen (O2) and glucose by triggering vessels dilation.
- Healing: scar tissues are formed to seal off damaged regions.
Blood-Brain Barrier
- Isolates brain from the body's interstitial fluid; protects the brain from harmful substances.
- Tight junctions in endothelial cells selectively allow specific substances to pass.
- Drugs, toxins, viruses, pathogens are blocked by the barrier.
- The permeability of the blood-brain barrier is weaker in specific brain regions, such as the hypothalamus and the medulla.
Active Transport
- Energy is needed to pump chemicals from the bloodstream into the brain.
- Essential for delivering nutrients (glucose, hormones, amino acids, vitamins) to the brain.
Nourishment of Vertebrate Neurons
- Neurons rely heavily on glucose.
- Brains require a high amount of oxygen (20% of the body's total oxygen consumption).
Nourishment of Vertebrate Neurons (Part 2)
- Thiamine (vitamin B₁) is needed to use glucose efficiently, deficiency leads to neuron damage (Korsakoff's syndrome).
How the Blood-Brain Barrier Works
- Illustrates how different types of molecules pass through the blood-brain barrier, regulating entry and exit, based on factors such as lipid solubility or active transport.
Schwann cells and Oligodendrocytes
- Myelin-producing glial cells; wrap around axons, increasing conduction velocity.
- Difference between oligodendrocytes in the central nervous system and schwann cells in the peripheral nervous system lies in how they insulate axons.
The Myelin Sheath
- Fatty substance wrapping around axons.
Myelin Speeds Up Neuron Signal Transmission
- Myelin sheath is an essential component for improving the speed at which neurons transfer signals via saltatory conduction.
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Test your knowledge of key concepts in neuroscience with this quiz. Questions cover neuron structure, brain functions, and historical contributions to our understanding of the mind and body. Challenge yourself to see how well you know the fundamentals of the nervous system!