Podcast
Questions and Answers
What are the two principal types of cells in nervous tissue?
What are the two principal types of cells in nervous tissue?
What is the resting membrane potential dependent on?
What is the resting membrane potential dependent on?
What type of potentials are brief, short-distance signals within a neuron?
What type of potentials are brief, short-distance signals within a neuron?
What do synapses transmit signals between?
What do synapses transmit signals between?
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What are neurons?
What are neurons?
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Which functions are associated with the nervous system?
Which functions are associated with the nervous system?
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What does the Central Nervous System (CNS) include?
What does the Central Nervous System (CNS) include?
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What does the Peripheral Nervous System (PNS) consist of?
What does the Peripheral Nervous System (PNS) consist of?
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What are the divisions of the PNS?
What are the divisions of the PNS?
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What does the sensory division of the PNS do?
What does the sensory division of the PNS do?
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What does the motor division of the PNS do?
What does the motor division of the PNS do?
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What does the motor division of the PNS include?
What does the motor division of the PNS include?
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What are the support cells in the nervous system called?
What are the support cells in the nervous system called?
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Which cells are part of the neuroglia in the CNS?
Which cells are part of the neuroglia in the CNS?
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What are the divisions of the autonomic nervous system?
What are the divisions of the autonomic nervous system?
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What are the functions of neuroglia in the CNS?
What are the functions of neuroglia in the CNS?
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Which cells produce myelin sheaths around nerve fibers in the CNS?
Which cells produce myelin sheaths around nerve fibers in the CNS?
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What are the main receptive regions of neurons?
What are the main receptive regions of neurons?
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What is the conducting region of the neuron?
What is the conducting region of the neuron?
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What cells are vital to the regeneration of damaged peripheral nerve fibers in the PNS?
What cells are vital to the regeneration of damaged peripheral nerve fibers in the PNS?
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What surrounds neuron cell bodies in the PNS and has similar functions to astrocytes in the CNS?
What surrounds neuron cell bodies in the PNS and has similar functions to astrocytes in the CNS?
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What are the armlike extensions from the cell body of a neuron?
What are the armlike extensions from the cell body of a neuron?
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What is the specialized function of neurons?
What is the specialized function of neurons?
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What organelles are present in neuron cell bodies for protein synthesis?
What organelles are present in neuron cell bodies for protein synthesis?
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What is the protective structure for neuron cell bodies?
What is the protective structure for neuron cell bodies?
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What do neurons require for their high metabolic rate?
What do neurons require for their high metabolic rate?
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What are the distal endings of axons known as?
What are the distal endings of axons known as?
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What is the main function of dendrites?
What is the main function of dendrites?
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What is the structural classification of neurons based on the number of processes extending from the cell body?
What is the structural classification of neurons based on the number of processes extending from the cell body?
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Which type of neuron is the most common in humans?
Which type of neuron is the most common in humans?
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Where are bipolar neurons typically found?
Where are bipolar neurons typically found?
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What is the main function of unipolar neurons in the PNS?
What is the main function of unipolar neurons in the PNS?
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How are neurons functionally grouped based on the direction of nerve impulse transmission relative to the CNS?
How are neurons functionally grouped based on the direction of nerve impulse transmission relative to the CNS?
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Which type of neuron transmits impulses from sensory receptors towards the CNS?
Which type of neuron transmits impulses from sensory receptors towards the CNS?
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What is the main function of motor neurons?
What is the main function of motor neurons?
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What is the function of interneurons within the CNS?
What is the function of interneurons within the CNS?
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What leads to the generation of resting membrane potential in neurons?
What leads to the generation of resting membrane potential in neurons?
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Which type of ion channels regulate ion movement across cellular membranes in neurons?
Which type of ion channels regulate ion movement across cellular membranes in neurons?
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What determines the direction of ion movement across the neuron membrane?
What determines the direction of ion movement across the neuron membrane?
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What drives the net flow of ions in and out of the neuron cell?
What drives the net flow of ions in and out of the neuron cell?
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What is the main function of myelin sheaths in the nervous system?
What is the main function of myelin sheaths in the nervous system?
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What type of cells form myelin sheaths in the peripheral nervous system (PNS)?
What type of cells form myelin sheaths in the peripheral nervous system (PNS)?
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What is the role of myelin sheath gaps in the peripheral nervous system (PNS)?
What is the role of myelin sheath gaps in the peripheral nervous system (PNS)?
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What is the main function of nonmyelinated nerve fibers in the nervous system?
What is the main function of nonmyelinated nerve fibers in the nervous system?
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In the central nervous system (CNS), what type of cells form myelin sheaths?
In the central nervous system (CNS), what type of cells form myelin sheaths?
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What is the role of axonal transport in neurons?
What is the role of axonal transport in neurons?
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What is the function of the initial segment of the axon in motor neurons?
What is the function of the initial segment of the axon in motor neurons?
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What is the main function of axon terminals in neurons?
What is the main function of axon terminals in neurons?
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What is the role of motor proteins and microtubules in axonal transport?
What is the role of motor proteins and microtubules in axonal transport?
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What is the function of the Golgi apparatus in neurons?
What is the function of the Golgi apparatus in neurons?
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What is the main function of the rough endoplasmic reticulum in neurons?
What is the main function of the rough endoplasmic reticulum in neurons?
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What is the main function of myelinated fibers in nerve impulse transmission?
What is the main function of myelinated fibers in nerve impulse transmission?
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Which structure marks off the three primary brain vesicles during brain development?
Which structure marks off the three primary brain vesicles during brain development?
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What is the general function of the basal nuclei (basal ganglia)?
What is the general function of the basal nuclei (basal ganglia)?
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What is the main function of the blood-brain barrier in protecting the CNS?
What is the main function of the blood-brain barrier in protecting the CNS?
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What determines the complex structure of the adult brain during development?
What determines the complex structure of the adult brain during development?
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Which brain structure is associated with the Subthalamic Nuclei and substantia nigra?
Which brain structure is associated with the Subthalamic Nuclei and substantia nigra?
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What role do basal nuclei play in muscle movements?
What role do basal nuclei play in muscle movements?
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What do disorders of the basal nuclei include?
What do disorders of the basal nuclei include?
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Which brain structure forms 80% of the diencephalon and sorts sensory information to the cerebral cortex?
Which brain structure forms 80% of the diencephalon and sorts sensory information to the cerebral cortex?
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What is the main function of the hypothalamus?
What is the main function of the hypothalamus?
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What are the mammillary bodies in the hypothalamus?
What are the mammillary bodies in the hypothalamus?
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What does the thalamus mediate in addition to relaying sensory information?
What does the thalamus mediate in addition to relaying sensory information?
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Where is the Subthalamic Nuclei located in the brain?
Where is the Subthalamic Nuclei located in the brain?
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What is the function of the epithalamus in the brain?
What is the function of the epithalamus in the brain?
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What is the main function of the basal nuclei?
What is the main function of the basal nuclei?
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What brain structure influences homeostasis and autonomic nervous system activity?
What brain structure influences homeostasis and autonomic nervous system activity?
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What brain structure plays a vital role in overall body homeostasis?
What brain structure plays a vital role in overall body homeostasis?
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What is the main function of the hypothalamus?
What is the main function of the hypothalamus?
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Which gland is part of the epithalamus and helps regulate the sleep-wake cycle?
Which gland is part of the epithalamus and helps regulate the sleep-wake cycle?
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What is the ultimate cause of Parkinson's disease?
What is the ultimate cause of Parkinson's disease?
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Which part of the brain stem is responsible for relaying information between the motor cortex and cerebellum?
Which part of the brain stem is responsible for relaying information between the motor cortex and cerebellum?
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What is the collective function of the midbrain, pons, and medulla oblongata in the brain stem?
What is the collective function of the midbrain, pons, and medulla oblongata in the brain stem?
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What is the role of the periaqueductal gray matter in the midbrain?
What is the role of the periaqueductal gray matter in the midbrain?
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Which part of the midbrain is involved in visual reflexes?
Which part of the midbrain is involved in visual reflexes?
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What is the function of the substantia nigra in the midbrain?
What is the function of the substantia nigra in the midbrain?
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What is the main function of the pons in the brain stem?
What is the main function of the pons in the brain stem?
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What is the most inferior part of the brain stem that blends gradually into the spinal cord?
What is the most inferior part of the brain stem that blends gradually into the spinal cord?
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Which nucleus in the hypothalamus regulates the sleep-wake cycles?
Which nucleus in the hypothalamus regulates the sleep-wake cycles?
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What does the hypothalamus use to trigger the release of antidiuretic hormone for controlling water balance and thirst?
What does the hypothalamus use to trigger the release of antidiuretic hormone for controlling water balance and thirst?
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Which area of the Cerebral Cortex is responsible for emotional impact and memory formation?
Which area of the Cerebral Cortex is responsible for emotional impact and memory formation?
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What is the primary function of the Anterior Association Area (prefrontal cortex) in the Cerebral Cortex?
What is the primary function of the Anterior Association Area (prefrontal cortex) in the Cerebral Cortex?
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What is the role of the Posterior Association Area in the Cerebral Cortex?
What is the role of the Posterior Association Area in the Cerebral Cortex?
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What is lateralization of Cortical Functioning?
What is lateralization of Cortical Functioning?
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What is the function of Association fibers in the Cerebral White Matter?
What is the function of Association fibers in the Cerebral White Matter?
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Which structure is primarily involved in movement control and is located deep within the cerebral white matter?
Which structure is primarily involved in movement control and is located deep within the cerebral white matter?
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What type of fibers transmit sensory information to the cerebral cortex and motor output from it?
What type of fibers transmit sensory information to the cerebral cortex and motor output from it?
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Which fibers connect corresponding gray areas of the two cerebral hemispheres?
Which fibers connect corresponding gray areas of the two cerebral hemispheres?
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What is the function of commissural fibers in the Cerebral White Matter?
What is the function of commissural fibers in the Cerebral White Matter?
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Which region of each cerebral hemisphere is responsible for communication within the cortex and with lower CNS centers?
Which region of each cerebral hemisphere is responsible for communication within the cortex and with lower CNS centers?
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What are the myelinated fibers in the Cerebral White Matter classified as?
What are the myelinated fibers in the Cerebral White Matter classified as?
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Which structures are involved in the control of movement and are located deep within the cerebral white matter?
Which structures are involved in the control of movement and are located deep within the cerebral white matter?
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Which part of the brain accounts for about 83% of total brain mass?
Which part of the brain accounts for about 83% of total brain mass?
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What is the main component of gray matter in the brain?
What is the main component of gray matter in the brain?
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What is the main component of white matter in the brain?
What is the main component of white matter in the brain?
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What is the main function of the cerebral cortex in the nervous system?
What is the main function of the cerebral cortex in the nervous system?
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Which imaging techniques reveal that specific motor and sensory functions are localized in discrete cortical areas called Domains?
Which imaging techniques reveal that specific motor and sensory functions are localized in discrete cortical areas called Domains?
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What is the basic pattern of the central nervous system (CNS)?
What is the basic pattern of the central nervous system (CNS)?
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How are the brain ventricles filled and lined?
How are the brain ventricles filled and lined?
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What connects the third ventricle with the fourth ventricle in the brain?
What connects the third ventricle with the fourth ventricle in the brain?
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Where are the occipital lobes located in the skull?
Where are the occipital lobes located in the skull?
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What are the three basic regions of each cerebral hemisphere?
What are the three basic regions of each cerebral hemisphere?
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What do modern imaging techniques reveal about the localization of higher mental functions in the cortex?
What do modern imaging techniques reveal about the localization of higher mental functions in the cortex?
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What is the main function of the brain stem?
What is the main function of the brain stem?
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Study Notes
Neuron Classification and Function
- Neurons are structurally classified as multipolar, bipolar, or unipolar based on the number of processes extending from the cell body.
- Multipolar neurons, the most common type in humans, have three or more processes, including one axon and multiple dendrites.
- Bipolar neurons possess two processes—an axon and a dendrite—found in special sense organs like the retina and olfactory mucosa.
- Unipolar neurons have a single short process that divides into proximal and distal branches, functioning mainly as sensory neurons in the PNS.
- Functionally, neurons are grouped as sensory, motor, and interneurons based on the direction of nerve impulse transmission relative to the CNS.
- Sensory neurons, mainly unipolar, transmit impulses from sensory receptors towards the CNS, with long peripheral processes.
- Motor neurons, multipolar, carry impulses away from the CNS to effector organs like muscles and glands.
- Interneurons, also multipolar, act as association neurons within the CNS, facilitating signal integration in neural pathways.
- Neurons have a resting membrane potential due to differences in ion concentration and permeability across their membranes.
- Membrane ion channels, including chemically gated, voltage-gated, and mechanically gated channels, regulate ion movement across cellular membranes.
- Electrochemical gradients, comprising concentration and electrical gradients, determine the direction of ion movement across the membrane.
- The resting membrane potential is generated by the balance between the chemical and electrical gradients, driving the net flow of ions in and out of the cell.
Neuron Structure and Function
- Nerve impulses are generated and transmitted along the axolemma, typically away from the cell body.
- In motor neurons, the nerve impulse is generated at the initial segment of the axon and conducted to the axon terminals.
- Axon terminals release neurotransmitters into the extracellular space, which either excite or inhibit neurons, muscle, or gland cells.
- Axons lack rough endoplasmic reticulum and a Golgi apparatus, relying on the cell body for protein synthesis and efficient transport mechanisms.
- Axonal transport occurs in both anterograde (away from the cell body) and retrograde (toward the cell body) directions, facilitated by motor proteins and microtubules.
- Myelin sheaths protect and electrically insulate nerve fibers, increasing the transmission speed of nerve impulses.
- Myelin sheaths in the peripheral nervous system (PNS) are formed by Schwann cells, while in the central nervous system (CNS), they are formed by oligodendrocytes.
- Myelin sheaths in the PNS contain myelin sheath gaps called Nodes of Ranvier and an outer collar of perinuclear cytoplasm (neurilemma).
- Nonmyelinated nerve fibers associated with Schwann cells in the PNS are thin fibers and are covered by the long extensions of adjacent glial cells in the CNS.
- Myelinated fibers conduct nerve impulses rapidly, while nonmyelinated fibers conduct impulses more slowly.
- In the PNS, myelin sheaths are formed by Schwann cells, which wrap themselves around the axon in a jelly roll fashion, gradually squeezing out cytoplasm to form the myelin sheath.
- Myelin sheaths in the CNS lack an outer collar of perinuclear cytoplasm, and the smallest-diameter axons are nonmyelinated and covered by the long extensions of adjacent glial cells.
Functional and Structural Areas of the Cerebral Cortex
- The Cerebral Cortex is divided into functional and structural areas, including the primary motor and somatosensory cortex, multimodal association areas, and anterior, posterior, and limbic association areas.
- The Anterior Association Area, also known as the prefrontal cortex, is involved in intellect, complex learning, recall, personality, and contains working memory.
- The Posterior Association Area plays a role in recognizing patterns, faces, spatial localization, sensory integration, and language comprehension.
- The Limbic Association Area, which includes the cingulate gyrus, parahippocampal gyrus, and hippocampus, is responsible for emotional impact and memory formation.
- Lateralization of Cortical Functioning involves the division of labor between the cerebral hemispheres, with the left hemisphere dominant for language, math, and logic in about 90% of people.
- The remaining 10% may have reversed or shared hemisphere functions, and right-cerebral-dominant individuals are often left-handed.
- The two cerebral hemispheres have almost instantaneous communication and complete functional integration, with each hemisphere having specific abilities.
- Cerebral White Matter, the second region of each cerebral hemisphere, is responsible for communication within the cortex and with lower CNS centers, consisting of myelinated fibers classified as association, commissural, or projection fibers.
- Association fibers connect different parts of the same hemisphere, while commissural fibers connect corresponding gray areas of the two hemispheres, with the largest commissure being the Corpus Callosum.
- Projection fibers transmit sensory information to the cerebral cortex and motor output from it, connecting the cortex to the rest of the nervous system and the body's receptors and effectors.
- The Basal Nuclei, deep within the cerebral white matter, are involved in the control of movement, and include the caudate nucleus, putamen, and globus pallidus.
- The caudate nucleus, putamen, and globus pallidus are the primary structures forming the basal nuclei, and are primarily involved in movement control.
Development and Structure of the Adult Brain
- The adult brain is composed of four main regions: Cerebral Hemispheres, Diencephalon, Brain Stem, and Cerebellum.
- Gray matter consists of nonmyelinated neurons and neuron cell bodies, while white matter consists mostly of myelinated axons with some nonmyelinated axons, primarily in fiber tracts.
- The brain ventricles are filled with cerebrospinal fluid and lined by ependymal cells, and they are continuous with each other and with the central canal of the spinal cord.
- The cerebral hemispheres are the most visible parts of the brain and account for about 83% of total brain mass.
- The cerebral hemispheres consist of cortex, white matter, and basal nuclei, and are divided into lobes - frontal, parietal, temporal, occipital, and insula.
- The cerebral cortex is the "Executive Suite" of the nervous system, composed of gray matter and containing billions of neurons arranged in six layers.
- Modern imaging techniques, such as PET scans and functional MRI scans, reveal that specific motor and sensory functions are localized in discrete cortical areas called Domains.
- The basic pattern of the central nervous system (CNS) is a central cavity surrounded by gray matter, external to which is white matter.
- The third ventricle is continuous with the fourth ventricle via the cerebral aqueduct that runs through the midbrain.
- The cerebral hemispheres fit snugly in the skull, with the occipital lobes located well superior to the posterior cranial fossa.
- Each of the cerebral hemispheres has three basic regions: a superficial cerebral cortex of gray matter, internal white matter, and basal nuclei.
- Many higher mental functions, such as memory and language, appear to be spread over large areas of the cortex in overlapping domains.
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Description
Test your knowledge of neuron classification, structure, and function with this quiz. Explore the different types of neurons, their functions, and the role of membrane potential in nerve impulse transmission. Dive into the structure of axons, myelin sheaths, and the process of axonal transport. Ideal for students and professionals in neuroscience, biology, or related fields.