Neuromuscular Junction and Muscle Contraction Quiz

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Questions and Answers

Which structure is located between a nerve fiber and a muscle fiber?

  • Motor unit
  • Motor pool
  • Motor end plate (MEP) (correct)
  • Excitation-contraction coupling

What is the main component of the motor pool?

  • Skeletal muscle
  • Anterior horn cells (AHCs) (correct)
  • Motor end plate (MEP)
  • Nerve fibers

What is the main function of the neuromuscular junction (NMJ)?

  • To transmit electrical signals from the muscle fiber to the motor neuron
  • To transmit electrical signals from the motor neuron to the muscle fiber (correct)
  • To produce and regulate contractile proteins in the muscle fiber
  • To store and release calcium ions for muscle contraction

Which proteins form the contractile proteins in skeletal muscles?

<p>Actin and myosin (C)</p> Signup and view all the answers

What does the motor unit consist of?

<p>Motor neuron + its axon + muscle fibers (B)</p> Signup and view all the answers

What is responsible for transmitting electrical signals from the motor neuron to the muscle fiber?

<p>Neuromuscular transmission (The end plate potential, EPP) (B)</p> Signup and view all the answers

What is the function of Troponin T in muscle contraction?

<p>Binds to tropomyosin (B)</p> Signup and view all the answers

During muscle contraction, what leads to the movement of tropomyosin laterally, uncovering the binding sites of actin for the myosin heads?

<p>Binding of troponin C with calcium (A)</p> Signup and view all the answers

Which structure is responsible for the rapid spread of the action potential in muscle fibers?

<p>T-tubules (A)</p> Signup and view all the answers

What is the energy source required for the mechanism of muscle contraction?

<p>Breakdown of ATP by ATPase activity of myosin heads in the presence of Ca++ ions (C)</p> Signup and view all the answers

What is the function of troponin I during muscle contraction?

<p>Inhibits binding of actin to myosin (A)</p> Signup and view all the answers

What is the role of myosin heads during muscle contraction?

<p>Breakdown of ATP to ADP by ATPase activity (A)</p> Signup and view all the answers

Which protein keeps actin structure and covers actin binding sites during muscle contraction?

<p>Tropomyosin (C)</p> Signup and view all the answers

What is the function of troponin C during muscle contraction?

<p>Binds with calcium (A)</p> Signup and view all the answers

What is the function of sarcotubular system in muscle contraction?

<p>Rapid spread of action potential (D)</p> Signup and view all the answers

What leads to muscle relaxation during excitation-contraction coupling?

<p>Breakdown of ATP by active Ca++ pump (B)</p> Signup and view all the answers

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Study Notes

Neuromuscular Junction (NMJ)

  • The neuromuscular junction (NMJ) is located between a nerve fiber and a muscle fiber.
  • The main function of the NMJ is to transmit electrical signals from the motor neuron to the muscle fiber.

Motor Unit

  • The motor unit consists of a motor neuron and all the muscle fibers it innervates.

Muscle Contraction

  • Actin and myosin form the contractile proteins in skeletal muscles.
  • The motor unit is responsible for transmitting electrical signals from the motor neuron to the muscle fiber.
  • During muscle contraction, the binding of calcium to troponin C leads to the movement of tropomyosin laterally, uncovering the binding sites of actin for the myosin heads.
  • The myosin heads pull the actin filament towards the center of the sarcomere, causing muscle contraction.
  • Tropomyosin keeps the actin structure and covers actin binding sites during muscle contraction, preventing muscle contraction.

Muscle Relaxation

  • The troponin I and troponin T complex helps to relax the muscle by blocking the binding of myosin heads to actin.

Muscle Fiber

  • The T-tubular system is responsible for the rapid spread of the action potential in muscle fibers.
  • The energy source required for the mechanism of muscle contraction is ATP.

Proteins and their Functions

  • Troponin T helps to relax the muscle by blocking the binding of myosin heads to actin.
  • Troponin I helps to regulate muscle contraction and relaxation.
  • Troponin C binds to calcium, leading to muscle contraction.
  • Sarcotubular system helps to regulate muscle contraction and relaxation by controlling the release and uptake of calcium ions.

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