10 Questions
What is the mechanism of breakdown of Atracurium?
Spontaneous plasma hydrolysis (Hoffman degradation)
Which of the following is NOT a therapeutic use of Non-depolarizing NMBs?
Pain management
What is the effect of high doses of Non-depolarizing NMBs?
Respiratory paralysis
What is the reversal agent for Rocuronium and Vecuronium?
Sugammadex
What is the mechanism of action of Non-depolarizing NMBs?
Competitive block of acetylcholine receptors
Which of the following is a side effect of High-dose Pancuronium?
Tachycardia
What is the enzyme responsible for metabolizing Mivacurium?
Pseudo-cholinesterase
What is the effect of Histamine release caused by Non-depolarizing NMBs?
Hypotension
What is the mechanism of reversal of Non-depolarizing NMBs by Neostigmine?
Displacement of competitive blockers from the receptor
Which of the following is NOT a feature of Atracurium?
Metabolism by liver
Test your knowledge on the classification of Neuromuscular blockers, including their mechanism of action, therapeutic uses, and side effects. Learn about depolarizing and non-depolarizing blockers, and their pharmacogenetic implications.
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