Snell’s Clinical Neuroanatomy Chapter 7 - Cerebrum

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Questions and Answers

What is the functional significance of fibers crossing the midline in the habenular commissure?

  • Enabling independent control of each limb, unaffected by the other side.
  • Connecting olfactory, visceral, and somatic afferent pathways from both sides of the brain. (correct)
  • Integrating somatosensory information exclusively from the face.
  • Facilitating direct motor control from one hemisphere to the other.

Lesions in which area of the diencephalon would most likely result in the disruption of circadian rhythms?

  • Pineal gland (correct)
  • Subthalamus
  • Mammillary bodies
  • Habenular nuclei

Why would damage to the thalamus result in significant loss of cerebral function?

  • It serves as a key relay station for sensory information (excluding olfaction) to the cerebral cortex. (correct)
  • It serves both hemispheres equally; damaging it removes redundancy.
  • It directly controls motor output to the peripheral nervous system.
  • It integrates cortical processing with other brain areas.

How does the pineal gland influence the function of the anterior pituitary gland?

<p>By inhibiting the release of gonadotropic hormone. (C)</p> Signup and view all the answers

What functional deficits would most likely be observed in a patient with a lesion restricted to the subthalamic nucleus?

<p>Exaggerated involuntary movements (B)</p> Signup and view all the answers

Based on their anatomical location, which of the following structures is most vulnerable to compression by a tumor in the sella turcica?

<p>Optic chiasm (B)</p> Signup and view all the answers

What is the primary functional consequence of damage to the internal capsule?

<p>Motor and sensory deficits on the contralateral side of the body. (C)</p> Signup and view all the answers

What is the most direct functional consequence of severing the corpus callosum?

<p>Compromised interhemispheric communication (D)</p> Signup and view all the answers

Which cellular change would most likely cause Alzheimer plaques?

<p>The excessive accumulation of proteins such as beta amyloid. (B)</p> Signup and view all the answers

Following a traumatic brain injury, a patient exhibits a complete loss of sensation on the left side of their body. Imaging reveals damage primarily to a specific structure within the diencephalon. What structure is most likely damaged?

<p>The right thalamus (B)</p> Signup and view all the answers

A patient presents with violent, involuntary movements confined to the right arm and leg. What specific area of the brain is most likely affected?

<p>The left subthalamic nucleus (D)</p> Signup and view all the answers

A 50-year-old patient reports progressive memory loss and disorientation, along with personality changes. A PET scan reveals diminished cortical metabolism. Which neurotransmitter is suspected to be the cause?

<p>Acetylcholine (D)</p> Signup and view all the answers

In a patient undergoing treatment for hydrocephalus, a shunt is placed to bypass a blockage in the interventricular foramen. Where will this shunt directly drain excess cerebrospinal fluid?

<p>The third ventricle (C)</p> Signup and view all the answers

After a stroke, a patient is unable to recognize objects placed in their left hand while their vision is occluded, yet can identify the same objects with their right hand. Where is the stroke most likely located?

<p>Corpus callosum (B)</p> Signup and view all the answers

A researcher is studying the effects of a novel drug on the habenular nuclei in rats. If the drug successfully targets its intended area, which of the following structures would be expected to show altered activity?

<p>The hippocampus and amygdaloid nucleus (C)</p> Signup and view all the answers

A neurosurgeon is planning a surgical approach to remove a tumor located near the pineal gland. What is the most important consideration in order to avoid damaging structures critical for the pupillary light reflex?

<p>Avoiding interruption to the posterior commissure. (C)</p> Signup and view all the answers

During a neurological exam, a physician observes that the patient has difficulty with fine motor movements and displays signs of spasticity. Which pathway from the internal capsule has most likely been affected?

<p>Corticospinal fibers projecting primarily to the trunk. (C)</p> Signup and view all the answers

What clinical observations would most strongly suggest a lesion affecting the uncinate fasciculus in the brain?

<p>Deficits in emotional processing related to olfactory discrimination. (B)</p> Signup and view all the answers

A patient undergoing neurosurgical intervention suddenly develops a fever, becomes hypertensive, and exhibits abnormal posturing. Where is the lesion likely affecting?

<p>Hypothalamus (C)</p> Signup and view all the answers

A patient with an interruption to the medial longitudinal stria exhibits dysfunction in which area?

<p>Intercommunication between the two occipital lobes (B)</p> Signup and view all the answers

Damage to the splenium of the corpus callosum creates issues with which kind of tasks?

<p>Transfer of visual information (D)</p> Signup and view all the answers

What key structure must a neurosurgeon be concerned with damaging when performing a surgery near the foramen of Monro?

<p>Fornix (D)</p> Signup and view all the answers

You have a patient with damage to the splenium of the corpus callosum. What side of the brain is the information unable to reach if you hold an item in the patient's left hand?

<p>Right side somatosensory (C)</p> Signup and view all the answers

Given that the mammillary bodies possess a central core of gray matter, what kind of cells do you also expect to see in the surrounding areas?

<p>A capsule of myelinated nerve fibers. (C)</p> Signup and view all the answers

If you were to inject a dye into the lateral ventricle, what is the next site you would expect to find the dye if all structures are functioning correctly?

<p>Third Ventricle (A)</p> Signup and view all the answers

Given the components of the epithalamus, what do you expect to see elevated with limited light exposure?

<p>Melatonin (A)</p> Signup and view all the answers

What is the purpose of the precentral gyrus, and where can you expect to find sensory input?

<p>Initiate motor function; lies adjacent to the central sulcus (D)</p> Signup and view all the answers

What is the key property of the central sulcus, and what gyri does it connect?

<p>The only sulcus of length to indent the superomedial border between two parallel gyri; connects the precentral and postcentral gyri (D)</p> Signup and view all the answers

Given the key role of the thalamus, what area is it in direct communication with?

<p>The cerebral cortex (C)</p> Signup and view all the answers

What clinical observations would arise with a lesion to the pulvinar?

<p>Disrupted visual processing (C)</p> Signup and view all the answers

What is the function of the lentiform nucleus, and what properties does it have?

<p>The control of muscular movement; a wedge shape mass broad convex base (D)</p> Signup and view all the answers

What is true of the Tela Choroidea, and where is it located?

<p>Located above the thalamus; it is composed of pia mater (B)</p> Signup and view all the answers

If it was observed that a patient has olfactory disruptions, what nuclei is damaged?

<p>The Habenular Nuclei (C)</p> Signup and view all the answers

Where could you expect the red nucleus to be found?

<p>Subthalamus (A)</p> Signup and view all the answers

What are the major components of the corpus striatum? What can be said about it?

<p>Lentiform and Caudate; lies lateral to the thalamus. (C)</p> Signup and view all the answers

In Alzheimer's patients, which areas show effects of neuron death?

<p>The hippocampus and entorhinal cortex (B)</p> Signup and view all the answers

Which area of the brain if destroyed shows no sign or symptom?

<p>Corpus Callosum (D)</p> Signup and view all the answers

Which aspect of the diencephalon's structure facilitates the crossing of nerve fibers for functional integration?

<p>The midline structure with symmetrical right and left halves (B)</p> Signup and view all the answers

How does the hypothalamic sulcus contribute to the functional organization of the diencephalon?

<p>It defines the separation between the thalamus and hypothalamus. (C)</p> Signup and view all the answers

What is the functional consequence of the pineal gland releasing melatonin into the third ventricle?

<p>Inhibition of gonadotrophic hormone release (A)</p> Signup and view all the answers

What is the significance of the internal capsule's close relationship to the lentiform nucleus in terms of potential clinical outcomes?

<p>It means tumors in either structure can cause significant motor or sensory deficits. (B)</p> Signup and view all the answers

How would severing the stria medullaris thalami impact the function of the habenular nucleus?

<p>It would impair the reception of afferent fibers from the amygdaloid nucleus. (B)</p> Signup and view all the answers

How does the unique structural characteristic of the pineal gland influence its endocrine function?

<p>The absence of a blood-brain barrier facilitates hormone secretion. (D)</p> Signup and view all the answers

What is the functional relevance of the connections between the subthalamic nucleus and the corpus striatum?

<p>Control of muscle activity (B)</p> Signup and view all the answers

Why is the thalamus considered a critical structure for overall cerebral function, and what broad deficits arise from its damage?

<p>It integrates and relays most sensory information, resulting in widespread functional loss. (C)</p> Signup and view all the answers

How does the position of the optic chiasma relative to the hypophysis inform treatment considerations for pituitary tumors?

<p>It mandates monitoring visual fields due to potential compression. (A)</p> Signup and view all the answers

What is the probable outcome of a lesion affecting the habenular commissure?

<p>Disrupted communication between olfactory integration centers. (B)</p> Signup and view all the answers

If an obstruction occurs at the interventricular foramen, what consequences would accurately describe downstream effects?

<p>Hydrocephalus in lateral ventricles (D)</p> Signup and view all the answers

If a patient has damage to the medial longitudinal stria, what would be the most likely result?

<p>Difficulties with interconnected inputs (D)</p> Signup and view all the answers

How do the commissure fibers facilitate communication between cortical regions?

<p>Enable the two hemispheres to share information and coordinate functions efficiently (C)</p> Signup and view all the answers

Which symptom is LEAST likely to indicate issues with the hypothalamus?

<p>Difficulty breathing (B)</p> Signup and view all the answers

How does the corona radiata contribute functionally to cerebral activity?

<p>Radiates projection fibers, integrating widespread cortical areas. (D)</p> Signup and view all the answers

What role does the tela choroidea play in maintaining CSF balance?

<p>Generates choroid plexus for generating cerebrospinal fluid. (D)</p> Signup and view all the answers

How does the relative surface area of gyri and sulci impact cerebral cortex function?

<p>The larger surface area in sulci results in the folding allowing a larger brain. (C)</p> Signup and view all the answers

While performing a surgery, what structure's location is most sensitive to damage when performing surgery near foramen Monoro leading to acute hydrocephalus?

<p>Tela choroidea (B)</p> Signup and view all the answers

In the context of cerebral anatomy, what implication does the organization of white matter have for recovery after stroke?

<p>Interconnectedness can enhance opportunities for rewiring. (C)</p> Signup and view all the answers

The optic chiasm intersects which area?

<p>Lamina terminalis (B)</p> Signup and view all the answers

Damage to the splenium has implications for information traveling between which two lobes?

<p>Temporal and Occipital (C)</p> Signup and view all the answers

Compared to an adult patient with the same pineal tumor, what unique symptom might be noticed more readily in a child?

<p>Severe alteration of reproductive function (A)</p> Signup and view all the answers

A patient presents with the clinical signs of Kluver-Bucy Syndrome along with olfactory hallucinations. What area is most likely to be impacted?

<p>Limbic System and Olfactory Cortex (B)</p> Signup and view all the answers

Which condition may arise from disruption to the anterior/posterior commisures?

<p>Contralateral loss following stroke (D)</p> Signup and view all the answers

A tumor on the thalamus can affect which area?

<p>Optic radiation (A)</p> Signup and view all the answers

The Lentiform nucleus is related through ____ to the ______?

<p>Lateral capsule/caudate (B)</p> Signup and view all the answers

What is a typical symptom that might arise from a damaged caudate nucleus?

<p>Difficulties with planned movements (B)</p> Signup and view all the answers

The frontal lobe is subdivided into superior, middle, and inferior by two ____?

<p>Sulci (B)</p> Signup and view all the answers

The most inferior aspect of the diencephalon's inferior surface is the?

<p>Mammillary bodies (B)</p> Signup and view all the answers

What feature is related to a patient's thalamus?

<p>Sensory input (C)</p> Signup and view all the answers

What function would be impacted with issues at tectum of the midbrain?

<p>Olfactory response (A)</p> Signup and view all the answers

How does the blood drain into the tela choroidea and into the ventricles?

<p>Tela choroida arteries derived from choroidal arteries (B)</p> Signup and view all the answers

If a patient presented with a severe head trauma, what structure would a doctor check given its association to the pineal stalk?

<p>Habenuclear and posterior commissures (D)</p> Signup and view all the answers

How can the pituitary compress the optic chiasma, and what symptom is a key indicator?

<p>It resides directly below structure/decrease peripheral vision (A)</p> Signup and view all the answers

What provides support and insulation for fibers?

<p>Glial Cells (A)</p> Signup and view all the answers

A tumor affecting the epithalamus would directly impact which of the following?

<p>Integration of olfactory, visceral, and somatic sensory information. (D)</p> Signup and view all the answers

What challenge would a neurologist face when diagnosing a lesion strictly confined to the claustrum?

<p>Subtle or absent clinical symptoms. (C)</p> Signup and view all the answers

Disruption to the blood supply of the tela choroidea would most significantly affect the:

<p>Production and composition of cerebrospinal fluid. (A)</p> Signup and view all the answers

What unique functional role does the anterior commissure play in facilitating interhemispheric communication?

<p>Connecting the right and left temporal lobes. (D)</p> Signup and view all the answers

A lesion affecting the subthalamic nucleus is most likely to produce:

<p>Sudden, forceful involuntary movements. (C)</p> Signup and view all the answers

What anatomical concept explains why a small hemorrhage in the internal capsule can produce widespread contralateral effects?

<p>The compact concentration of essential nerve fibers within the structure. (A)</p> Signup and view all the answers

What best describes the anatomical organization of the cerebral cortex?

<p>Heterogeneous areas with specialized functions, organized into anatomically distinct lobes and gyri. (C)</p> Signup and view all the answers

In what manner does the pineal gland mediate its inhibitory effects on the pituitary gland?

<p>Via cerebrospinal fluid transport to the anterior pituitary. (C)</p> Signup and view all the answers

If a patient was undergoing neurological decline, what findings during a brain scan would be most suggestive of Alzheimer's pathology?

<p>Diminished cortical metabolism in the temporal and parietal regions. (A)</p> Signup and view all the answers

What is the functional significance of the interthalamic connection?

<p>It may play a role in coordinating activity between the thalami. (D)</p> Signup and view all the answers

How might damage to the mammillary bodies impact behavior?

<p>Disturbances in memory and cognitive processes. (C)</p> Signup and view all the answers

A lesion confined to the fornix would most directly disrupt:

<p>Efferent system of the hippocampus to the mammillary bodies. (A)</p> Signup and view all the answers

Given the anatomical relationship of structures on the inferior surface of the diencephalon, what is a potential risk of an expanding pituitary tumor?

<p>Compression of the optic chiasma. (C)</p> Signup and view all the answers

What distinguishes the calcarine sulcus from other major sulci of the cerebral cortex regarding its function?

<p>Its containment of the primary visual cortex. (A)</p> Signup and view all the answers

In an individual affected by hydrocephalus due to a blockage near the interventricular foramen, what indirect affect could stem from this event?

<p>Compression of fibers in the internal capsule. (D)</p> Signup and view all the answers

Surgical intervention targeting the pineal gland carries increased risk to what neurological function?

<p>Visual reflexes. (C)</p> Signup and view all the answers

What is the primary anatomical distinction between the long and short association fibers in the cerebrum?

<p>The groups of gyri they connect. (D)</p> Signup and view all the answers

When examining a horizontal section of the brain, what key anatomical feature helps distinguish the lentiform nucleus from the caudate nucleus?

<p>The intervening band of nerve fibers forming the internal capsule. (D)</p> Signup and view all the answers

Why is the lateral sulcus a critical landmark for regional localization in the cerebrum?

<p>It demarcates the boundary between the frontal and temporal lobes. (C)</p> Signup and view all the answers

What is the primary mechanism by which lesions in the thalamus result in significant loss of cerebral function?

<p>By blocking sensory relay to the cerebral cortex. (C)</p> Signup and view all the answers

What role do the habenular nuclei and commissure play in the broader context of diencephalic function?

<p>Integration of somatic, visceral, and olfactory afferent pathways. (A)</p> Signup and view all the answers

What distinguishes the functional organization of motor areas in the gyrus anterior to the central sulcus?

<p>The cell bodies are responsible for initiating movement of the contralateral side of the body. (B)</p> Signup and view all the answers

What constitutes the anatomical basis for the clinical sign of headache aggravation with changing head position in patients with a colloid cyst of the third ventricle?

<p>The cyst blocking the foramen of Monro. (D)</p> Signup and view all the answers

What is the relationship between melatonin production within the pineal gland and sleep disorders?

<p>Melatonin production increases during darkness. (A)</p> Signup and view all the answers

Following a stroke, which describes the significance of white matter organization for potential recovery?

<p>Intact white matter promotes neuroplasticity and functional reorganization. (A)</p> Signup and view all the answers

What impact does substantial damage to the hippocampus have on areas within the cerebral cortex?

<p>Inputs to mammillary bodies can be reduced. (A)</p> Signup and view all the answers

What critical function is uniquely served by the cerebral commissures, and what is the major structure?

<p>Communication is facilitated. The structure is the corpus callosum. (C)</p> Signup and view all the answers

In what way does the hypothalamus influence the function of peripheral endocrine glands?

<p>It regulates the release of anterior pituitary hormones. (D)</p> Signup and view all the answers

The telencephalon forms the central core of the cerebrum, while the diencephalon forms the cerebral hemispheres.

<p>False (B)</p> Signup and view all the answers

The diencephalon is symmetrically divided by the tentorium cerebelli.

<p>False (B)</p> Signup and view all the answers

The hypothalamus integrates autonomic and endocrine functions, playing a key role in maintaining homeostasis.

<p>True (A)</p> Signup and view all the answers

Damage solely to the thalamus does not typically result in significant loss of cerebral function.

<p>False (B)</p> Signup and view all the answers

The inferior surface of the diencephalon is entirely concealed within the intact brain.

<p>False (B)</p> Signup and view all the answers

The interthalamic connection always exists as a large, solid structure connecting the two halves of the thalamus.

<p>False (B)</p> Signup and view all the answers

Unlike other sensory pathways, the olfactory pathway directly involves the thalamus as a key relay station.

<p>False (B)</p> Signup and view all the answers

The corpora quadrigemina are part of the diencephalon.

<p>False (B)</p> Signup and view all the answers

The internal capsule is a nucleus.

<p>False (B)</p> Signup and view all the answers

The interventricular foramina facilitate communication between the third ventricle and the cerebral aqueduct.

<p>False (B)</p> Signup and view all the answers

The hypothalamus is located dorsal to the thalamus.

<p>False (B)</p> Signup and view all the answers

The anterior commissure connects the cerebral hemispheres and is larger than the corpus callosum.

<p>False (B)</p> Signup and view all the answers

The precentral gyrus, responsible for somatic sensation, is located posterior to the central sulcus.

<p>False (B)</p> Signup and view all the answers

The Pineal gland possesses a functional blood-brain barrier.

<p>False (B)</p> Signup and view all the answers

The calcarine sulcus is primarily located on the lateral surface of the hemisphere.

<p>False (B)</p> Signup and view all the answers

Association fibers connect the cortex to the brain stem.

<p>False (B)</p> Signup and view all the answers

Concretions of calcified material called brain sand progressively accumulate within the pineal gland with age.

<p>True (A)</p> Signup and view all the answers

The hypothalamus controls the functions of the somatic nervous system.

<p>False (B)</p> Signup and view all the answers

The optic chiasm is strictly related to vision and serves no part in hormonal regulation.

<p>False (B)</p> Signup and view all the answers

The fornix is mainly composed of sensory nerve fibers.

<p>False (B)</p> Signup and view all the answers

Match the following diencephalon structures with their relative position:

<p>Thalamus = Superior to the hypothalamus Hypothalamus = Inferior to the thalamus Subthalamus = Inferolateral to the hypothalamus Epithalamus = Posterior to the thalamus</p> Signup and view all the answers

Match each cerebral lobe with its primary function/location:

<p>Frontal Lobe = Executive functions, motor control Parietal Lobe = Sensory processing, spatial orientation Temporal Lobe = Auditory processing, memory Occipital Lobe = Visual processing</p> Signup and view all the answers

Match each component of the basal nuclei with its description:

<p>Caudate Nucleus = Closely related to the lateral ventricle Lentiform Nucleus = Has a broad, convex base directed laterally Claustrum = Separated from the lentiform nucleus by the external capsule Amygdaloid Nucleus = Located in the temporal lobe close to the uncus</p> Signup and view all the answers

Match each part of the corpus callosum with its description:

<p>Rostrum = Prolonged posteriorly to be continuous with the lamina terminalis Genu = Curved anterior end that bends inferiorly in front of the septum pellucidum Body = Arches posteriorly and extends laterally Splenium = Thickened posterior portion</p> Signup and view all the answers

Match the ventricle walls with their boundaries:

<p>Anterior Wall = Formed by the lamina terminalis, across where the anterior commissure runs Posterior Wall = Formed by the opening into the cerebral aqueduct, plus the posterior commissure Lateral Wall = Formed by the medial surface of the thalamus superiorly and the hypothalamus inferiorly Superior Wall = Formed by the roof of the third ventricle</p> Signup and view all the answers

Match the structures with the features located on the inferior surface of the diencephalon:

<p>Optic Chiasma = Most anterior structure Tuber Cinereum = Convex mass of gray matter, continuous with the infundibulum Infundibulum = Hollow, becomes continuous with the posterior lobe of the hypophysis cerebri. Mammillary Bodies = Two small hemispherical bodies</p> Signup and view all the answers

Match the sulci with the areas they separate:

<p>Central Sulcus = Separates the frontal lobe from the parietal lobe Lateral Sulcus = Separates the temporal lobe from the frontal and parietal lobes Parieto-occipital Sulcus = Separates the parietal lobe from the occipital lobe Calcarine Sulcus = Located primarily within the occipital lobe.</p> Signup and view all the answers

Match the commissure fibers to their correct definition:

<p>Corpus Callosum = The largest commissure of the brain, connecting the two cerebral hemispheres Anterior Commissure = Connects the right and left temporal lobes Posterior Commissure = Fibers from the pretectal nuclei, involved in the pupillary light reflex Fornix = Connects the hippocampal formation to the mammillary bodies of the hypothalamus</p> Signup and view all the answers

Match the following internal capsule structures with their anatomical relationships:

<p>Anterior Limb = Lies between the head of the caudate nucleus and the lentiform nucleus Genu = The bend in the internal capsule between the other two limbs Posterior Limb = Lies between the thalamus and the lentiform nucleus Corona Radiata = Continuation of the internal capsule consisting of projections in various directions</p> Signup and view all the answers

Match the conditions with the affected areas:

<p>Alzheimer Disease = Associated with the formation of senile plaques and neurofibrillary tangles in cortical areas. Thalamic Lesions = Often result from thrombosis or hemorrhage, leading to sensory impairments on the contralateral side of the body Subthalamic Lesions = Can result in involuntary movements called hemiballismus, due to damage in extrapyramidal motor nuclei Hypothalamic Syndromes = Result from infection, trauma, or vascular disorders, leading to imbalance or genital irregularities</p> Signup and view all the answers

Flashcards

Cerebrum

Largest part of the brain, located in the anterior and middle cranial fossae.

Diencephalon

Central core of the cerebrum, includes the third ventricle.

Telencephalon

Forms the cerebral hemispheres.

Gross Features of the Diencephalon

Inferior surface of the diencephalon, visible in the intact brain.

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Third Ventricle

Divides diencephalon into halves.

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Four Parts of Diencephalon

Divisions: thalamus, subthalamus, epithalamus, and hypothalamus.

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Thalamus

Relay station for sensory systems (except olfactory).

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Subthalamic Nucleus

Involved in muscle activity control.

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Habenular Nucleus

Center for integration of olfactory, visceral, and somatic pathways.

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Habenular Nucleus function

Integrates olfactory, visceral and somatic pathways.

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Pineal Gland

Influences pituitary, pancreas, parathyroids, adrenals, and gonads.

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Pineal Gland's Role

Regulates reproductive function, produces melatonin.

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Hypothalamus

Extends from optic chiasma to mammillary bodies, controls autonomic functions.

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Preoptic Area

Area anterior to the lamina terminalis and anterior commissure.

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Optic Chiasma

Bundle of nerve fibers at junction of anterior wall and floor of third ventricle.

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Tuber Cinereum

Convex mass of gray matter, continuous with infundibulum.

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Mammillary Bodies

Hemispherical bodies posterior to tuber cinereum.

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Third Ventricle

Slitlike cleft between the two thalami.

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Lamina Terminalis

Thin sheet of gray matter forming anterior wall of 3rd ventricle.

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Posterior wall of third ventricle

The point where the aqueduct and pineal recess are located.

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Lateral wall of third ventricle

Lateral and superior to the hypothalamic sulcus.

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Inferior wall of third ventricle

Formed by the optic chiasma, tuber cinereum, infundibulum, and mammillary bodies.

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Longitudinal Cerebral Fissure

Deep midline fissure separating cerebral hemispheres.

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Corpus Callosum

Connects hemispheres across the midline.

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Falx Cerebri

Fold of dura mater separating hemispheres.

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Cerebral Lobes

Divisions that name area based on related cranial bones.

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Precentral Gyrus

Contains motor cells initiating contralateral movements.

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Lateral Sulcus

Horizontal on inferior and lateral surfaces.

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Parieto-occipital Sulcus

Begins on medial margin, passes downward to meet calcarine sulcus.

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Calcarine Sulcus

Commences under posterior end of corpus callosum, arches to occipital pole.

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Frontal Lobe

Anterior to central sulcus, superior to lateral sulcus.

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Parietal Lobe

Posterior to central sulcus, superior to lateral sulcus.

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Temporal Lobe

Inferior to lateral sulcus.

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Occipital Lobe

Area behind parieto-occipital sulcus.

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Corpus Callosum (medial)

Forms striking view on medial surface.

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Cingulate Gyrus

Runs above corpus callosum until posterior end.

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Paracentral Lobule

Cortex surrounding indentation by central sulcus on superior border.

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Precuneus

Area bounded by the upturned posterior end of cingulate sulcus and parieto-occipital sulcus.

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Cuneus

Triangular area of cortex.

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Collateral Sulcus

Inferior surface, runs underneath calcarine sulcus.

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Colloid Cyst Headache

Aggravation of headache due to the cyst's mobility blocking the foramen of Monro.

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Cerebral Hemisphere Components

Each hemisphere has a cortex, basal nuclei, and a lateral ventricle.

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Inferior Surface of Hypothalamus

Formed by hypothalamic structures: optic chiasma, infundibulum, tuber cinereum, and mammillary bodies.

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Fornix

Thick bundle of fibers from the hippocampus, arches over the thalamus.

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Stria Medullaris Thalami

Afferent nerve fibers to habenular nucleus, forms a ridge along the superior margin.

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Habenular Commissure

Superior part of the base of the pineal stalk.

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Posterior Commissure

Inferior part of the base of the pineal stalk.

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Brain Sand

Calcified material concretions that accumulate in the pineal gland with age.

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Pineal Gland Secretions

Exerts inhibitory actions, influencing hormone production of other glands.

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Uncinate Fasciculus

Connects the frontal gyri with the temporal lobe.

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Cingulum

Lies within white matter of the cingulate gyrus, connecting frontal and parietal.

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Inferior Longitudinal Fasciculus

Bundle that runs anteriorly from pole of occipital lobe to temporal lobe.

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Internal Capsule

The fibers form a compact band that connects to and from the brainstem.

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Commissure Fibers

Myelinated fibers that connect brain hemispheres.

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Association fibers

Connect cortical regions within same hemisphere.

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Projection Fibers

Afferent and efferent nerve fibers, connect brainstem to cerebral cortex.

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Forceps Minor

Fibers curving forward into the frontal lobes from the genu.

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Forceps Major

Fibers arching back into the occipital lobe from the splenium.

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Stria Terminalis

Channel connecting amygdaloid to the diencephalon.

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Lateral Surface of Diencephalon

Bounded by the internal capsule, connects cortex to brainstem and spinal cord.

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Alveus

Layer closest to brain matter on the medial and inferior surfaces

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Caudate Nucleus

C-shaped mass of gray matter closely related to the lateral ventricle.

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Internal Capsule Hemorrhage

Most common cause is atheromatous degeneration with hypertension.

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Lentiform Nucleus

Mass of gray matter that is wedged shaped with lateral base and medial axis.

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Claustrum Location

Is anterior or posterior to the lentiform but lateral to the capsule.

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Amygdaloid Nucleus

Area that is medial to the cortex in the temporal area next to the uncus.

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Genu Location

Area anterior to the brain but posterior to the body

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Rostrum Description

A short bridge of white matter connecting the genu and body

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Cerebral Hemispheres Internal Structure

Located in the interior of cerebral hemispheres; lateral ventricles, basal nuclei, and nerve fibers.

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Lateral Ventricles Definition

Cavities in cerebral hemispheres containing cerebrospinal fluid (CSF).

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Corpus Striatum

Includes the caudate nucleus and lentiform nucleus; separated by the internal capsule.

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Internal Capsule Function

Afferent and efferent fibers travel through cerebral cortex and the brainstem.

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Corona Radiata

Radiating projection fibers from internal capsule.

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Commissure Fibers Function

Contains fibers interconnecting symmetrical cortical areas.

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Superior Longitudinal Fasciculus

Connects frontal lobe to occipital; largest bundle.

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Cerebral Hemispheres

Largest part of the brain, derived from the telencephalon.

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Epithalamus

It consists of the habenular nuclei and the pineal gland.

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Fornix Composition

Composed of myelinated fibers & efferent from the hippocampus.

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Cerebral Cortex

The surface is formed by fiber bundles and cortex.

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Subthalamus location hint

Lies inferior & lateral to the hypothalamus.

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Internal Capsule positioning

This band is flanked by the caudate nucleus and the thalamus.

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Study Notes

Cerebrum Objectives

  • Introduction targets complexities of the forebrain, defining the diencephalon, accurately locating the thalamus and hypothalamus through brain section study, understanding ascending/descending tract positions, and highlighting pathologic site—internal capsule. The internal capsule is a frequent target of pathologic lesions.

Colloid Cyst Case

  • A 23-year-old man shows intermittent headaches, dizziness, left leg weakness/numbness, aggravated by head movement.
  • CT scan detects a small, white, opaque ball at the anterior of the third ventricle.
  • Resulting diagnosis: colloid cyst of the third ventricle.
  • Headache aggravation stems from cyst mobility within the choroid plexus; head repositioning blocks the foramen of Monro, raising intracranial pressure and hydrocephalus.
  • Left leg weakness/numbness arises from tumor pressure on the right thalamus and tracts in the right internal capsule.
  • Successfully treated via surgical excision of tumor.

General Info

  • Cerebral hemispheres originate from the telencephalon and compose the largest brain portion.
  • Each hemisphere includes a gray matter cortex, internal gray matter masses (basal nuclei), plus a lateral ventricle.
  • Knowledge of anatomical structure is necessary for comprehending complexities tied to functional localization.

Divisions

  • The cerebrum is the brain's largest part, located in the anterior and middle cranial fossae, filling the vault concavity.
  • Divisible into the diencephalon (central core) and telencephalon (cerebral hemispheres).

Diencephalon makeup and boundaries

  • Features the third ventricle and its bounding structures.
  • It spans between the cerebral aqueduct posteriorly and interventricular foramina anteriorly.
  • Structure arrangement is symmetrical, midline, split into right and left halves.
  • Subdivisions are for convenience, nerve fibers freely cross boundaries for functional integration. It is continuous with the cerebral aqueduct

Basic features

  • Only area seen on the intact brain's surface is the diencephalon's inferior surface.
  • It is formed by hypothalamic structures that feature, anterior to posterior: Optic chiasma with optic tracts, the infundibulum with the tuber cinereum, and mammillary bodies.
  • The superior surface is hidden by the fornix (fiber bundle from hippocampus arching over the thalamus to join the mammillary body).

Diencephalon Walls

  • Consists of an ependyma layer continuous with the third ventricle
  • Superiorly covered by a vascular pia mater fold (tela choroidea of the third ventricle).
  • Choroid plexuses of the third ventricle project downward from midline to cavity.
  • The lateral surface is defined by the internal capsule (white matter) that conveys connective nerve fibers.
  • The medial surface is split in half vertically to mirror each other.
  • There are a number of components to the medial surface (lateral wall), and a shallow Sulcus called the hypothalamic sulcus lies at the boundary.
  • Superior regions of the medial surface features the Thalamus
  • Inferiorly features the hypothalamus
  • The stria medullaris thalami runs along the superior margin of the medial surface.
  • The diencephalon is divided into; thalamus, subthalamus, epithalamus, and hypothalamus

Thalamus Facts

  • The thalamus is a large egg-shaped gray matter mass.
  • It makes up most of the Diencephalon.
  • The thalamus relays cells to all sensory parts of your body.
  • Olfactory is the only region not relayed by the thalamus.
  • Relays information to the cerebral cortex while working closely with the cortex to do other key functions.
  • It is a sensory cell station.
  • Activities involve integration and relay to cortex and many subcortical areas.
  • It plays a role in somatic (body) and visceral (organ) functions.

Internal anatomy

  • The caudate nucleus, Then thalamus, lastly hippocampus.
  • The claustrum is a fine sheet of gray matter that lines the external surface.
  • The main nerve that runs through the cerebrum is the white nervous tissue.
  • The white matter has 3 categories; connections with the Commisural fibers, Assocication fibres, Projection fibres.
    • Commisural Fibres essentially connects all hemisphere regions
      • Ex; corpus callosum
      • Ex; anterior commisure
      • Ex; posterior commisure
      • Ex; fornix
      • ex; habenular commisure
  • The corpus callosum is the main major connection of the 2 brain sections.
    • Has Rostrum sections
      • Has a Genu secton
      • Body segments
      • And splenium
  • Rostrum fibres extend anteriorly
  • The Genu Curves anteriorily
  • the fibers form into the forceps Minor.
  • Main body fibers are bundles of radiata. - These bodies go to the cerebral cortex. - Some fibers that make up the interior lateral walls, and lateral vertriciles
  • these are called the tapedum
  • lateral fibers in splenium arch backward into occipital lobe and are called Forceps Major
    • anterior commisure, small nerve with fibers along midline on lamina terminalis
      • Some fibers curve back from sides by grooving inferior lentiorm nucleus.
      • bundle connect to the Para sympathetic in oculomotor nuclei.

<new_section>

###White Matter

  • White matter has myelinated fibers, and are supported by neuroglia. Three connection types:
  • Commissural Fibers
  • Association Fibers
  • Projection Fibers.

###Commissure Fibers

  • Connect corresponding areas of the two hemispheres including, corpus callosum, anterior commissure, posterior commissure, along with the fornix and the habenular commissure.
  • Corpus callosum description: largest brain commissure links the cerebral hemispheres, lies at the base, featuring Rostrum, Genu, Body and Splenium.
    • Fibers in the Rostrum extend anteriorly.
    • Fibers in the Genu curve anteriorly forming Forceps Minor.
    • The fibers of the body extend laterally forming the corona radiata, intersecting association and projection fibers en route to the cerebral cortex.
    • Fibers create the roof and lateral wall of the ventricles
    • tapetum fibers
  • The lateral fibers in splenium curve back to to the occipital lobe - Forceps Major
  • Anterior commissure is small nerve, features fiber midline on lamina terminalis.
  • Fibres curve back from sides by grooving inferior lentiform nucleus, bundle connects to the parasympathetic in oculomotor nuclei.
  • Commissure fibers connect symmetrical brain regions through corpus callosum, anterior commissure, posterior commissure, fornix, and habenular commissure.
    • The anterior commissure sends fibers towards temporal lobes The Claustrum is a thin grey layer on the outer surface of of the Lentiform Nucleus </new_section>

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