Podcast
Questions and Answers
What is the primary goal of antiviral and antiretroviral drugs?
What is the primary goal of antiviral and antiretroviral drugs?
- Target essential bacterial enzymes
- Enhance viral entry into host cells
- Activate viral replication
- Inhibit a pathway unique to the virus but not the cell (correct)
What are viruses' requirements for reproduction?
What are viruses' requirements for reproduction?
- Generate energy to reproduce
- Utilize their own enzymes for reproduction
- Infect a cell, use the host machinery to synthesize macromolecules necessary for assembly of new viral particles (correct)
- Rely solely on external sources for reproduction
What do viruses contain?
What do viruses contain?
- Only RNA, not DNA
- Only DNA, not RNA
- DNA and RNA both
- Capsule and envelope but not DNA or RNA (correct)
Are viruses susceptible to antibacterial agents?
Are viruses susceptible to antibacterial agents?
What are the stages of the viral life cycle?
What are the stages of the viral life cycle?
How do viruses attach to host cells?
How do viruses attach to host cells?
What process is involved in the entry stage of the viral life cycle for some viruses like HIV and measles?
What process is involved in the entry stage of the viral life cycle for some viruses like HIV and measles?
What is the primary component of antiviral and antiretroviral drugs that makes them effective against viruses?
What is the primary component of antiviral and antiretroviral drugs that makes them effective against viruses?
What is the role of the envelope in some viruses?
What is the role of the envelope in some viruses?
What are obligate intracellular parasites?
What are obligate intracellular parasites?
Which of the following is a major challenge in treating viral infections?
Which of the following is a major challenge in treating viral infections?
What is the role of cytotoxic T lymphocytes in combating viral infections?
What is the role of cytotoxic T lymphocytes in combating viral infections?
What is the mechanism of action of nucleoside analogues such as Acyclovir and Ganciclovir?
What is the mechanism of action of nucleoside analogues such as Acyclovir and Ganciclovir?
Which virus is Valganciclovir particularly active against?
Which virus is Valganciclovir particularly active against?
What is the main toxic effect associated with Ribavirin?
What is the main toxic effect associated with Ribavirin?
What is the primary mechanism of action for Foscarnet in inhibiting viral infections?
What is the primary mechanism of action for Foscarnet in inhibiting viral infections?
How do Amantadine and Rimantadine act to prevent viral infections?
How do Amantadine and Rimantadine act to prevent viral infections?
What are the most common side effects associated with Amantadine and Rimantadine?
What are the most common side effects associated with Amantadine and Rimantadine?
'Selective Neuraminidase Inhibitors' are primarily used for the treatment of which viral infections?
'Selective Neuraminidase Inhibitors' are primarily used for the treatment of which viral infections?
'Viral M2 Protein Blockers' such as Amantadine and Rimantadine specifically prevent viral uncoating by blocking which viral protein?
'Viral M2 Protein Blockers' such as Amantadine and Rimantadine specifically prevent viral uncoating by blocking which viral protein?
Which category of drugs is described as substrates of cytochrome P-450 enzymes and prone to drug-drug interactions?
Which category of drugs is described as substrates of cytochrome P-450 enzymes and prone to drug-drug interactions?
Which drug is known to bind to the transmembrane glycoprotein subunit (gp41) of the viral envelope, preventing the fusion of viral envelope and cell membrane?
Which drug is known to bind to the transmembrane glycoprotein subunit (gp41) of the viral envelope, preventing the fusion of viral envelope and cell membrane?
Which of the following drugs is NOT an HIV protease inhibitor?
Which of the following drugs is NOT an HIV protease inhibitor?
Which drug is specifically mentioned as inhibiting viral assembly and release from the host CD4 cells?
Which drug is specifically mentioned as inhibiting viral assembly and release from the host CD4 cells?
Which drug is known to block certain strains of HIV from binding to chemokine receptor type 5 (CCR5), preventing viral entry?
Which drug is known to block certain strains of HIV from binding to chemokine receptor type 5 (CCR5), preventing viral entry?
Which drug is associated with changes in body fat distribution such as central obesity, buffalo hump, and gynecomastia as a general side effect?
Which drug is associated with changes in body fat distribution such as central obesity, buffalo hump, and gynecomastia as a general side effect?
Which drug is described as a substrate of cytochrome P-450 enzymes and prone to drug-drug interactions?
Which drug is described as a substrate of cytochrome P-450 enzymes and prone to drug-drug interactions?
Which category of drugs prevents attachment of viral proteins to host CD4 cells, thus inhibiting viral entry?
Which category of drugs prevents attachment of viral proteins to host CD4 cells, thus inhibiting viral entry?
Which drug binds to the transmembrane glycoprotein subunit (gp41) of the viral envelope, preventing the fusion of viral envelope and cell membrane?
Which drug binds to the transmembrane glycoprotein subunit (gp41) of the viral envelope, preventing the fusion of viral envelope and cell membrane?
Which drug is used for the treatment of both Influenza A and B?
Which drug is used for the treatment of both Influenza A and B?
What is the primary therapeutic option for Hepatitis C when used in combination with Ribavirin?
What is the primary therapeutic option for Hepatitis C when used in combination with Ribavirin?
Which drug is an alternative choice for the treatment of Hepatitis B?
Which drug is an alternative choice for the treatment of Hepatitis B?
Which drug needs to be injected subcutaneously?
Which drug needs to be injected subcutaneously?
Which drug is excreted unchanged in urine and is given orally?
Which drug is excreted unchanged in urine and is given orally?
What is the purpose of Highly Active Antiretroviral Therapy (HAART) used in the treatment of HIV/AIDS?
What is the purpose of Highly Active Antiretroviral Therapy (HAART) used in the treatment of HIV/AIDS?
What is the mechanism of action of Nucleoside Reverse Transcriptase Inhibitors (NRTIs) in HIV treatment?
What is the mechanism of action of Nucleoside Reverse Transcriptase Inhibitors (NRTIs) in HIV treatment?
What is a serious adverse effect of NRTIs in HIV treatment?
What is a serious adverse effect of NRTIs in HIV treatment?