Cours: Neural Crest Development

Which of the following is a derivative of neural crest cells?

What influences the fate of neural crest cells (NCCs)?

Which cell type is primarily associated with the peripheral nervous system as a derivative of neural crest cells?

Which of the following is NOT derived from neural crest cells?

What is the relationship between Schwann cell precursors and neural crest cells?

What is a significant finding regarding neural crest cells based on single cell RNA sequencing?

What method has contributed significantly to understanding the developmental trajectories of neural crest cells?

What do the lineage-restriction events in neural crest cells involve?

Which bioinformatics tools are utilized in the analysis of cell types in neural crest cells?

What aspect of neural crest cell development is underscored by the Confetti study mentioned in the content?

What is the primary characteristic of neural crest cells during their development?

Which types of structures are derived from cranial neural crest cells?

What process do neural crest cells undergo to become migratory?

What is a target tissue of neural crest cells that is involved in the peripheral nervous system?

During which developmental stage do neural crest cells emerge?

What is one method used to study neural crest cell derivatives?

What does the expression of Cre recombinase in neural crest cells allow researchers to do?

Which of the following is NOT a derivation from neural crest cells?

What structure is associated with the early stages of neural plate formation?

What type of migration do neural crest cells primarily undergo?

What is the primary purpose of the Neural Crest Culture System?

What did the clonal analysis in the early 1980s confirm about neural crest cells?

Which technique is primarily used to trace neural crest cells in confetti mice?

What finding did Chaya Kalcheim report about premigratory neural crest cells in chickens?

What is a notable feature of the Wnt1-CreERT system mentioned in the analysis?

During quantitative analysis, what was concluded about the majority of neural crest cells in mice?

What color representation is used in the confetti mice for tracing purposes?

In the context of the analysis, what does 'lineage-restricted' imply about a neural crest cell?

Which type of cells comprise a homogeneous population according to the culture system described?

What role does the CAGG promoter play in the context of the neural crest culture system?

What is the primary function of Cre-recombinase in genetic studies using mice?

Cre-recombinase is naturally found in the mouse genome.

Describe the role of LoxP sites in the Cre-recombinase system.

In the Cre-Lox system, the presence of a 'stopp signal' between LoxP sites prevents gene expression until it is ______ by Cre-recombinase.

Match the component with its function in the Cre-Lox recombination system:

Which type of cell in the cerebellum forms rosette synapses?

During cerebral cortex development, somal translocation involves migration along radial glia.

What is the primary type of migration exhibited by Purkinje precursor cells in the cerebellum?

Neural crest cells undergo a(n) ________ to mesenchymal transition during their migration.

Which of the following is NOT a target destination for neural crest cells?

Match the cell type with its respective location and function in the cerebellum:

Name the process that allows neural crest cells to migrate from the dorsal neural tube.

The migration of neural crest cells is independent of somite structures.

Which of the following best describes the function of CD271/p75NTR in neural crest cell analysis?

According to clonal analysis, neural crest stem cells (NCSCs) possess multipotency and self-renewal capacity in approximately 50% of the cells.

What is the role of Sox10 in the context of neural crest cell labeling?

The combination of Wnt1 and ______ allows self-renewal and produces new NCSCs.

What happens if Wnt1, BMP2 and TGF$\beta$ are applied alone to neural crest stem cells?

Match the following factors with their roles in neural crest stem cell (NCSC) development:

What is the primary conclusion drawn from combining in vitro and in vivo approaches in the study of neural crest stem cells?

Inactivation of the Tgfbr2 gene in neural crest stem cells promotes normal smooth muscle, bone, and cartilage formation.

Which of the following is a non-neural derivative of neural crest cells?

Neural crest cells only contribute to the formation of neural tissues.

What is the main advantage of using quail-chick chimeras in studying neural crest cell migration?

__________ are cells in the adrenal medulla that are derived from neural crest cells.

Match the following neural crest cell derivatives with their tissue type:

What is the key difference between the selective and instructive effects of factors on neural crest cell differentiation?

In neural crest cell culture, the entire neural tube is left in the dish for analysis.

In the context of neural crest cell fate determination, what does an 'instructive effect' imply?

In the context of neural crest cell research using the 'Confetti mouse,' what is the primary purpose of using a CreERT system?

According to the 'Confetti mouse' study, the majority of neural crest cells are lineage-restricted at the analyzed stage.

What is a key characteristic of p75/Sox10-positive neural crest-derived cells found in adult skin, as identified through in vivo fate mapping?

Genetic cell fate mapping utilizes Wnt1-CreERT to trace ______ neural crest cells.

Match the method with its corresponding application or outcome in neural crest cell research:

What does the concept of 'sequential lineage-restriction events' in neural crest cell differentiation imply?

Premigratory neural crest cells were understood to be lineage-restricted beginning in the 1980s.

What is the role of hormones, via estrogen-receptor, in the context of using Wnt1-CreERT?