Neural Action Potential and Propagation Quiz

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What is the resting membrane potential typically for a neuron?

-60 mV

What is the main role of K+ in generating membrane potential?

Balancing the (+) charges of intracellular cations

What is the function of the ATP-driven sodium-potassium pump?

Maintaining the concentration gradients of Na+ and K+

What contributes to the cell being more negative inside?

<p>K+ flowing out of the cell</p> Signup and view all the answers

What is the main reason for the separation of (+) and (-) charges across the membrane?

<p>Small buildup of (-) ions in cytosol along the inside of the membrane</p> Signup and view all the answers

What is the electrical property of neurons and synapse structure?

<p>Highly irritable or electrically excitable</p> Signup and view all the answers

What is the role of the leakage ion channels in the membrane?

<p>Enabling the diffusion of various ions at rest</p> Signup and view all the answers

What is the unit of measurement for potential energy in the context of the resting membrane potential?

<p>Millivolts</p> Signup and view all the answers

What neurotransmitter is involved in reward, motivation, and motor control?

<p>Dopamine</p> Signup and view all the answers

Which neurotransmitter is mainly inhibitory and produces a calming effect?

<p>GABA</p> Signup and view all the answers

What neurotransmitter is linked to pain control and pleasure?

<p>Endorphins</p> Signup and view all the answers

Which neurotransmitter is involved in controlling alertness and arousal?

<p>Norepinephrine</p> Signup and view all the answers

What neurotransmitter affects hunger, sleep, arousal, and mood?

<p>Serotonin</p> Signup and view all the answers

Which neurotransmitter activates the sympathetic nervous system by increasing heart rate and enlarging pupils?

<p>Epinephrine</p> Signup and view all the answers

What neurotransmitter is a major excitatory neurotransmitter involved in information transmission throughout the brain?

<p>Glutamate</p> Signup and view all the answers

Which neurotransmitter is released in excess during allergic reactions, causing swelling and inflammation of tissues?

<p>Histamine</p> Signup and view all the answers

Which cranial nerve controls most facial expressions and secretion of tears and saliva?

<p>Facial</p> Signup and view all the answers

Which cranial nerve is responsible for innervating the superior oblique muscle of the eye?

<p>Trochlear</p> Signup and view all the answers

Which cranial nerve is associated with the sense of smell?

<p>Olfactory</p> Signup and view all the answers

Which cranial nerve is responsible for controlling the trapezius and sternocleidomastoid muscles, as well as swallowing movements?

<p>Accessory</p> Signup and view all the answers

What is the result of excessive K+ efflux following action potential (AP)?

<p>After-hyperpolarization (undershoot)</p> Signup and view all the answers

What is the threshold for action potential (AP)?

<p>Depolarization reaches -55 to -50 mV</p> Signup and view all the answers

How is stimulus intensity coded?

<p>By frequency of action potentials</p> Signup and view all the answers

What is the function of absolute refractory period?

<p>Enforces one-way transmission</p> Signup and view all the answers

What is the effect of myelin sheath on the rate of action potential (AP) propagation?

<p>Dramatically increases</p> Signup and view all the answers

What is the role of the relative refractory period?

<p>Axon’s threshold for AP generation is substantially elevated</p> Signup and view all the answers

How do nerve fibers transmit impulses where speed is essential?

<p>More rapidly (100 m/s or more)</p> Signup and view all the answers

What is the role of all-or-none phenomenon in action potential (AP)?

<p>AP either happens completely or not at all</p> Signup and view all the answers

What is the range of impulse transmission speed in nerve fibers?

<p>100 m/s or more</p> Signup and view all the answers

What is the function of the after-hyperpolarization (undershoot)?

<p>Results from excessive K+ efflux following action potential (AP)</p> Signup and view all the answers

What is the effect of axon diameter on the rate of impulse propagation?

<p>Affects the rate of impulse propagation</p> Signup and view all the answers

What is the role of salutatory conduction?

<p>Occurs on myelinated axons</p> Signup and view all the answers

What is the main characteristic of graded potentials?

<p>They are short-lived, localized changes in membrane potential caused by stimuli</p> Signup and view all the answers

What triggers the opening of gated ion channels in response to graded potentials?

<p>Strength of the stimulus</p> Signup and view all the answers

What occurs when neurotransmitters released by another neuron influence a neuron beyond the synapse?

<p>Postsynaptic potentials</p> Signup and view all the answers

What is the process by which graded potentials add together, resulting in larger depolarizing or hyperpolarizing potentials?

<p>Summation</p> Signup and view all the answers

What is the main event in synapse structure involving the arrival of an action potential at the axon terminal?

<p>Release of neurotransmitters</p> Signup and view all the answers

What is the total amplitude of action potentials?

<p>Around 100 mV</p> Signup and view all the answers

Where do neurons and muscle cells typically generate action potentials?

<p>In axons</p> Signup and view all the answers

What is the state of gated Na+ and K+ channels during the resting state of a neuron?

<p>Closed</p> Signup and view all the answers

What characterizes the depolarizing phase of an action potential?

<p>Opening of voltage-gated Na+ channels</p> Signup and view all the answers

What characterizes the repolarizing phase of an action potential?

<p>Inactivation of Na+ channels and the opening of K+ channels</p> Signup and view all the answers

What occurs during hyperpolarization following an action potential?

<p>Some K+ channels remain open, and Na+ channels reset</p> Signup and view all the answers

What is the critical mechanism for transmitting signals over long distances in neurons?

<p>Action potential</p> Signup and view all the answers

Study Notes

Neural Action Potential and Propagation

  • After-hyperpolarization (undershoot) results from excessive K+ efflux following action potential (AP)
  • AP must be propagated along axon’s entire length for neuron signaling
  • AP self-propagates at constant velocity on unmyelinated axons (salutatory conduction on myelinated axons)
  • Threshold for AP is when depolarization reaches -55 to -50 mV
  • All-or-none phenomenon: AP either happens completely or not at all
  • Stimulus intensity is coded by frequency of AP, not by amplitude of individual APs
  • Absolute refractory period: from opening of Na+ channels until reset, enforces one-way transmission
  • Relative refractory period: following absolute refractory period, axon’s threshold for AP generation is substantially elevated
  • Nerve fibers transmit impulses more rapidly (100 m/s or more) where speed is essential
  • Axon diameter and myelination affect rate of impulse propagation
  • Myelin sheath dramatically increases rate of AP propagation
  • Electrical signals rely on four types of ion channels: leakage, ligand-gated, mechanically gated, and voltage-gated

Neurophysiology: Graded Potentials, Synapse Structure, and Action Potentials

  • Graded potentials are short-lived, localized changes in membrane potential caused by stimuli, resulting in depolarization or hyperpolarization.
  • Graded potentials vary in magnitude with the strength of the stimulus and trigger gated ion channels to open.
  • Postsynaptic potentials occur when neurotransmitters released by another neuron influence a neuron beyond the synapse.
  • Summation is the process by which graded potentials add together, resulting in larger depolarizing or hyperpolarizing potentials.
  • Synapse structure involves the arrival of an action potential at the axon terminal, followed by the release of neurotransmitters and their effects on the postsynaptic membrane.
  • Action potentials are brief reversals of membrane potential with a total amplitude of around 100 mV and do not decrease in strength with distance.
  • Neurons and muscle cells can generate action potentials, typically in axons, and involve depolarization, repolarization, and often hyperpolarization.
  • The resting state of a neuron involves closed gated Na+ and K+ channels, with leakage channels open.
  • The depolarizing phase of an action potential involves the opening of voltage-gated Na+ channels, allowing Na+ to rush into the cell and depolarize the membrane.
  • The repolarizing phase of an action potential involves the inactivation of Na+ channels and the opening of K+ channels, allowing K+ to rush out of the cell and contribute to repolarization.
  • Hyperpolarization occurs as some K+ channels remain open, and Na+ channels reset, temporarily making the membrane potential more negative than the resting level.
  • The action potential is a critical mechanism for transmitting signals over long distances and involves the opening and closing of voltage-gated channels in response to changes in membrane potential.

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