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Questions and Answers
Which part of the neuron acts as the main receptive input region?
Which part of the neuron acts as the main receptive input region?
What is the primary function of the myelin sheath?
What is the primary function of the myelin sheath?
In which direction does anterograde movement occur in an axon?
In which direction does anterograde movement occur in an axon?
What unique property do neurons possess concerning their ability to replicate?
What unique property do neurons possess concerning their ability to replicate?
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Which structure is responsible for transmitting nerve impulses away from the neuron cell body?
Which structure is responsible for transmitting nerve impulses away from the neuron cell body?
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What role do the Nodes of Ranvier play in neuron function?
What role do the Nodes of Ranvier play in neuron function?
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What is the primary characteristic of neuroglia cells?
What is the primary characteristic of neuroglia cells?
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What is the axon hillock?
What is the axon hillock?
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What initiates an action potential in a neuron?
What initiates an action potential in a neuron?
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What is the primary characteristic of unipolar neurons?
What is the primary characteristic of unipolar neurons?
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What happens during the process of depolarization?
What happens during the process of depolarization?
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Which type of synapse is characterized by the direct electrical coupling of two neurons?
Which type of synapse is characterized by the direct electrical coupling of two neurons?
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Which functional type of neuron transmits impulses from sensory receptors towards the CNS?
Which functional type of neuron transmits impulses from sensory receptors towards the CNS?
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What distinguishes gray matter from white matter in the nervous system?
What distinguishes gray matter from white matter in the nervous system?
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How is the resting potential of a neuron primarily maintained?
How is the resting potential of a neuron primarily maintained?
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Which type of synapse involves the release of neurotransmitters?
Which type of synapse involves the release of neurotransmitters?
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What type of neurons are almost all interneurons in the CNS classified as?
What type of neurons are almost all interneurons in the CNS classified as?
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Which ion's equilibrium potential primarily determines the resting potential of a neuron?
Which ion's equilibrium potential primarily determines the resting potential of a neuron?
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What is the primary function of the cerebral cortex?
What is the primary function of the cerebral cortex?
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Which type of cell in the cerebral cortex is characterized by a triangular shape and large nucleus?
Which type of cell in the cerebral cortex is characterized by a triangular shape and large nucleus?
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Which layer of the cerebellar cortex contains the highly branched granule cells?
Which layer of the cerebellar cortex contains the highly branched granule cells?
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The dorsal root of the spinal cord is primarily associated with which type of fiber?
The dorsal root of the spinal cord is primarily associated with which type of fiber?
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Astrocytes are primarily responsible for which of the following functions?
Astrocytes are primarily responsible for which of the following functions?
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What is the role of Purkinje cells in the cerebellar cortex?
What is the role of Purkinje cells in the cerebellar cortex?
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In the context of neuroglial cells, what function do Schwann cells serve?
In the context of neuroglial cells, what function do Schwann cells serve?
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Which division of the autonomic nervous system is associated with the thoracolumbar region?
Which division of the autonomic nervous system is associated with the thoracolumbar region?
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Study Notes
Nervous System
- Contains two major divisions: the central and peripheral nervous systems
- The central nervous system (CNS) consists of the brain and spinal cord
- The peripheral nervous system (PNS) is composed of nerves emerging from the CNS and ganglia
- Neuroglia are supporting cells that occupy space between neurons
Neurons
- The structural units of the nervous system
- Highly specialized cells that conduct messages as nerve impulses
- Have three key characteristics: extreme longevity, amitotic nature, and exceptionally high metabolic rates
- Consists of a cell body with one or more cell processes enclosed by neurolemma
- Nissl bodies are rough endoplasmic reticulum in the perikaryon
Nerve Cell Processes
- Dendrites are the main receptive input regions, providing a surface area for receiving signals from other neurons
- Dendrites convey incoming messages toward the cell body
- The axon is the conducting region of the neuron, generating nerve impulses and transmitting them away from the cell body
Axon Structure
- The axon hillock is the cone-shaped area of the cell body where the axon arises
- Axon terminals (synaptic knobs, boutons) are the knob-like distal endings of the terminal branches of axons
Axonal Transport
- Anterograde movement refers to movement toward the axon terminal
- Retrograde movement refers to movement away from the axon terminal
Myelin Sheath
- A whitish, fatty, segmented covering that protects and electrically insulates fibers
- Increases the speed of nerve impulse transmission
- Primarily associated with axons (dendrites are usually unmyelinated)
Saltatory Conduction
- The myelin sheath facilitates conduction along the axon
- Nodes of Ranvier are short gaps created by the myelin sheath along the axon
- Saltatory conduction, facilitated by the nodes of Ranvier, is faster than conduction in unmyelinated axons
Nerve Impulse Generation
- The ability of neurons to receive, conduct, and transmit signals relies on the opening and closing of specific ion channel proteins in their membranes
- During the resting potential, the concentration of Na+ ions is only 1/10th that of extracellular fluids, while the internal K+ ion concentration is about 10x greater than outside the cell, resulting in a potential difference of about -90mV (inside negative relative to the outside)
Depolarization and Action Potential
- Depolarization involves a sudden influx of extracellular Na+ ions that lowers the membrane potential (making the inside less negative)
- This is followed by an outflow of K+ ions that restores the resting potential
- These changes create an Action Potential
Synapse
- The specialized region of contact where neurotransmitters are released from an axon to stimulate another cell
- Junction that mediates information transfer from one neuron to the next, or from a neuron to an effector cell
Synapse Types
- Can be excitatory or inhibitory, depending on whether the transmitter depolarizes or hyperpolarizes the presynaptic membrane
- Types of synapses include axodendritic, axosomatic, axoaxonic, dendrodendritic, and dendrosomatic synapses
- Synapses can be classified as electrical or chemical
Neuron Classification By Structure
- Unipolar (Pseudounipolar): Single short process, found in ganglia
- Bipolar: Two processes (an axon and a dendrite), rare, found in some special sense organs (olfactory epithelium, retina)
- Multipolar: Three or more processes, most common, found in neurons of the cerebrum and cerebellum
Neuron Classification By Function
- Sensory (Afferent): Transmit impulses from sensory receptors toward the CNS, almost all are unipolar
- Motor (Efferent): Carry impulses away from the CNS to effector organs (muscles, glands), multipolar
- Interneurons: Lie between motor and sensory neurons, shuttle signals through CNS pathways (integration), almost all are multipolar
Neuron Distribution
- Gray matter: Contains cell bodies of neurons, dendrites, and terminations of axons arriving at the region
- White matter: Primarily composed of myelinated axons
Cerebral Cortex
- Has gray matter in the outer zone of the brain hemispheres
- Receives and analyzes sensory information from the body and initiates voluntary motor activity
- Involved in learning and memory
- Cells are arranged in six major layers
Cerebral Cortex Cell Types
- Pyramidal cell: Somatic shape is roughly triangular with a large vesicle-containing nucleus and abundant Nissl bodies
- Stellate or granule cell: Relatively small with numerous dendrites and a single short axon
- Horizontal cells: Primarily confined to one layer of the cortex, fusiform with radiating dendrites and short axons radiating in opposite directions
Cerebellar Cortex
- Receives information from the eyes, ears, and stretch receptors of the muscles
- Plays a crucial role in coordination, maintenance of balance, and posture
Cerebellar Cortex Layers
- Molecular layer: Contains few small neurons and many unmyelinated nerve fibers
- Middle layer: Consists of a single layer of large Purkinje cells
- Granule cell layer: Contains closely packed small cells with short dendrites and a single axon
Spinal Cord
- Receives motor commands from the brain and relays them to muscles and other effectors via spinal nerves
- Sensory fibers enter the cord through the dorsal root
- Motor fibers leave through the ventral root
- Spinal nerves are formed by the joining of dorsal and ventral roots
Spinal Cord Structure
- Gray matter is H-shaped and contains nerve cell bodies and their dendrites
- White matter surrounds gray matter and consists of dorsal, lateral, and ventral columns
Neuroglial Cells
- Astrocytes: Support structure, repair processes, form the blood-brain barrier, regulate metabolic exchange
- Oligodendrocytes: Produce myelin, provide electrical insulation
- Schwann cells: Produce myelin, provide electrical insulation
- Ependymal cells: Line cavities of the CNS
- Microglia: Macrophagic activity
Organization of the Nervous System
- Autonomic Nervous System (ANS): Thoracolumbar division is associated with the sympathetic division of the ANS
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Description
Explore the fundamental structures and functions of the nervous system in this quiz. Learn about the divisions of the nervous system, the role of neurons, and how nerve cell processes facilitate communication. Test your knowledge of neuroglia and neuronal characteristics.