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Questions and Answers
What is the primary function of neurons within the nervous system?
What is the primary function of neurons within the nervous system?
Which part of the neuron is responsible for receiving information from other neurons?
Which part of the neuron is responsible for receiving information from other neurons?
What characterizes multipolar neurons?
What characterizes multipolar neurons?
In which location are bipolar neurons primarily found?
In which location are bipolar neurons primarily found?
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What is the function of pseudounipolar neurons?
What is the function of pseudounipolar neurons?
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What distinguishes the basic functionality of glial cells compared to neurons?
What distinguishes the basic functionality of glial cells compared to neurons?
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Which part of the neuron conducts signals away from the cell body?
Which part of the neuron conducts signals away from the cell body?
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How do glial cells enhance neuronal function?
How do glial cells enhance neuronal function?
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What primarily determines the speed of action potential conduction in axons?
What primarily determines the speed of action potential conduction in axons?
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How do neurotransmitters cross the synaptic cleft?
How do neurotransmitters cross the synaptic cleft?
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What is the role of Ca2+ ions in the process of neurotransmitter release?
What is the role of Ca2+ ions in the process of neurotransmitter release?
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Which ions are involved when neurotransmitters bind to postsynaptic receptors?
Which ions are involved when neurotransmitters bind to postsynaptic receptors?
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What is the conduction speed for large-diameter, heavily myelinated axons?
What is the conduction speed for large-diameter, heavily myelinated axons?
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What happens when the presynaptic terminal is reached by an action potential?
What happens when the presynaptic terminal is reached by an action potential?
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What type of synapse is formed between two neurons?
What type of synapse is formed between two neurons?
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Which factor does NOT influence the conduction speed of action potentials in axons?
Which factor does NOT influence the conduction speed of action potentials in axons?
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What occurs in a postsynaptic cell when Na+ channels open?
What occurs in a postsynaptic cell when Na+ channels open?
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What effect do K+ or Cl− channels have on the postsynaptic cell?
What effect do K+ or Cl− channels have on the postsynaptic cell?
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How are neurotransmitters typically removed from the synaptic cleft?
How are neurotransmitters typically removed from the synaptic cleft?
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Which enzyme is responsible for breaking down acetylcholine in the synaptic cleft?
Which enzyme is responsible for breaking down acetylcholine in the synaptic cleft?
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What characterizes a converging neuronal pathway in the CNS?
What characterizes a converging neuronal pathway in the CNS?
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What principle describes the all-or-none response of action potentials?
What principle describes the all-or-none response of action potentials?
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What is the significance of hyperpolarization in a postsynaptic cell?
What is the significance of hyperpolarization in a postsynaptic cell?
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How does norepinephrine typically return to the presynaptic terminal after its release?
How does norepinephrine typically return to the presynaptic terminal after its release?
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Study Notes
Nervous System Overview
- The nervous system is responsible for receiving sensory input, integrating information, controlling muscles and glands, maintaining homeostasis, and establishing and maintaining mental activity.
- The nervous system is divided into two main components: the central nervous system (CNS) and the peripheral nervous system (PNS).
- The CNS includes the brain and spinal cord.
- The PNS includes all nervous tissue outside the CNS.
- The PNS can be further divided into the sensory division and the motor division.
- The sensory division carries signals from sensory receptors to the CNS.
- The motor division carries signals from the CNS to effector organs (muscles and glands).
- The divisions can further be divided into somatic nervous system and autonomic nervous system and enteric nervous system pathways.
Cells of the Nervous System
- Neurons receive stimuli, conduct action potentials, and transmit signals to other neurons or effector organs.
- Glial cells support neurons and maintain normal conditions in nervous tissue. The support cells are not responsible for action potentials unlike neurons.
- Astrocytes are major supporting cells in the CNS and can stimulate or inhibit neural activity. They also create the blood-brain barrier.
- Ependymal cells line cavities in the brain and spinal cord and hold cerebrospinal fluid.
- Microglial cells act as the immune defense of the CNS by removing bacteria and cellular debris.
- Oligodendrocytes and Schwann cells produce myelin for nerve axons within the CNS and PNS, respectively.
Neuron Structure
- Neurons have a cell body containing a nucleus.
- Dendrites extend from the cell body and receive information from other neurons and send it towards the cell body.
- Axons extend from the axon hillock, carry sensory signals to the CNS and motor signals away from it. and can be myelinated.
Neuron Types
- Multipolar neurons have many dendrites and a single axon. Most CNS and motor neurons are multipolar.
- Bipolar neurons have one dendrite and one axon. They are found in some sensory organs like the retina.
- Pseudo-unipolar neurons have one process that splits into two: one extending to the periphery and other to the CNS. They have sensory receptors at their periphery.
Myelin Sheath
- Myelin sheaths are specialized layers around axons in some neurons (myelinated).
- Myelin is produced by oligodendrocytes in the CNS and by Schwann cells in the PNS. Its insulation prevents most ion movement across the axon membrane.
- Nodes of Ranvier are gaps in the myelin sheath where ion movement can occur and greatly enhances the speed of the impulses. Myelinated axons exhibit saltatory conduction.
- Unmyelinated axons lack myelin and conduct action potentials in a continuous conduction manner, which is much slower than saltatory conduction.
Nervous Tissue Organization
- Nervous tissue is gray or white matter depending on the abundance of myelinated axons.
- Gray matter consists of neuron cell bodies and dendrites, with little myelin.
- White matter consists of bundles of parallel axons with myelin sheaths, appearing whitish in color.
Resting Membrane Potential
- All cells exhibit electrical properties at their membranes due to ion differences across it.
- The cell membrane is not permeable to ions. It is permeable through ion channels.
- Ions flow through leak channels or gated channels (voltage-gated and chemically gated), down their concentration gradient and along the electrical gradient.
- In most resting neurons, more K+ are inside and more Na+ is outside the membrane, which creates a negative charge inside the membrane, and a positive charge outside.
- The Sodium-Potassium pumps actively transport Na+ out and K+ in, which is responsible for maintaining the resting membrane potential.
Nerve Cell Communication
- Nerve cells are excitable; their resting membrane potential can change in response to stimuli.
- Changes in membrane potential are called action potentials, which allow cells to communicate.
Gated Membrane Channels
- Stimuli activate gated channels, opening and closing in response to specific signals.
- Changes in gated ion channel permeability affect membrane potential.
Action Potential
- Action potentials are electrical signals traveling along the cell membrane.
- Voltage-gated Na+ and K+ channels are involved in action potentials.
- A stimulus opens Na+ channels for a brief period, allowing Na+ to rapidly enter the cell; this depolarizes it.
- If the depolarization is strong enough (reaching threshold), more Na+ channels open, leading to a rapid depolarization.
- Na+ channels close, and K+ channels open, allowing K+ to leave the cell, leading to repolarization.
- Eventually, resting membrane potential is restored.
Action Potential Conduction
- Action potentials may travel as continuous or saltatory conduction (in myelinated axons).
Synapse
- Synapses are junctions where axons communicate with other neurons.
- Presynaptic terminals release neurotransmitters across a synaptic cleft to postsynaptic neurons.
- Ca2+ triggers the release of neurotransmitters via exocytosis.
- Neurotransmitters bind to receptors on the postsynaptic membrane.
- Resulting channel openings affect the postsynaptic neuron (depolarizing or hyperpolarizing it).
- Neurotransmitters are removed from the synaptic cleft to prevent continuous stimulation.
Neuronal Pathways
- Information transmission occurs in different pathways (converging and diverging pathways).
- Converging pathways allow multiple inputs to converge onto a single target and are essential for processing various stimuli.
- Diverging pathways allow a single input to be transmitted to multiple targets.
Summation
- Summation is required for integration of multiple signals onto a target neuron.
- Spatial summation involves signals from different locations on the postsynaptic cell.
- Temporal summation involves signals arriving at the postsynaptic cell in rapid succession.
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Description
This quiz covers the key components and functions of the nervous system, including the central and peripheral nervous systems. It also delves into the roles of neurons and glial cells, and the divisions within the peripheral nervous system. Test your knowledge on this vital biological system and its processes.