Nervous System Organization

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Questions and Answers

What is the primary function of the sympathetic nervous system?

  • Maintaining homeostasis during sleep
  • Promoting digestion and rest
  • Regulating blood pressure during exercise
  • Facilitating fight or flight responses (correct)

Which neurotransmitter is primarily released by postganglionic neurons of the sympathetic nervous system?

  • Acetylcholine
  • Dopamine
  • Serotonin
  • Noradrenaline (correct)

Where are most parasympathetic preganglionic neurons located?

  • In discrete ganglia near targets
  • Throughout the entire nervous system
  • In the cranial nerve nuclei and sacral spinal cord (correct)
  • In the spinal cord only

What is the primary role of the enteric nervous system?

<p>Controlling gut activity and digestion (C)</p> Signup and view all the answers

What distinguishes parasympathetic preganglionic neurons from sympathetic preganglionic neurons?

<p>Parasympathetic neurons have long, lightly myelinated axons (A)</p> Signup and view all the answers

Which of the following statements about postganglionic sympathetic neurons is true?

<p>They project mainly to smooth muscles, glands, or cardiac muscles (B)</p> Signup and view all the answers

What prepares the body for maintenance activities and rest?

<p>Parasympathetic nervous system (C)</p> Signup and view all the answers

Which cranial nerve is associated with parasympathetic preganglionic neurons?

<p>Cranial Nerve X (A)</p> Signup and view all the answers

What type of axons do postganglionic parasympathetic neurons have?

<p>Short, non-myelinated axons (A)</p> Signup and view all the answers

Which pathway do preganglionic sympathetic axons take to reach postganglionic neurons?

<p>Through the white ramus communicans (A)</p> Signup and view all the answers

What is the primary role of visceral sensory afferents in the autonomic nervous system?

<p>To send sensory information back to the spinal cord (C)</p> Signup and view all the answers

Which of the following adrenergic receptor types induces slow-acting responses in sympathetic targets?

<p>Various types based on intracellular signaling pathways (A)</p> Signup and view all the answers

What is the primary function of the Submucosal (Meissner's) plexus in the enteric nervous system?

<p>Managing secretions and blood flow in the gut (D)</p> Signup and view all the answers

Which factors influence the physiological effects of acetylcholine in the autonomic nervous system?

<p>The types of receptors it binds to (D)</p> Signup and view all the answers

What is the primary role of the Myenteric (Auerbach's) plexus in the enteric nervous system?

<p>To facilitate peristalsis and gut movements (C)</p> Signup and view all the answers

Preganglionic neurons in the intermediolateral horn primarily communicate with which structure to reach postganglionic neurons?

<p>Sympathetic chain (C)</p> Signup and view all the answers

What type of neurons in the myenteric plexus are responsible for measuring the degree of stretch in smooth muscles?

<p>Sensory neurons (B)</p> Signup and view all the answers

Which type of neurons in the submucosal plexus measure the chemical composition of the lumen?

<p>Sensory neurons (C)</p> Signup and view all the answers

Which neurons are primarily involved in coordinating peristaltic movement of the gut?

<p>Excitatory and inhibitory visceromotor neurons (A)</p> Signup and view all the answers

What role do interneurons play in the enteric nervous system?

<p>They connect sensory and motor neurons. (C)</p> Signup and view all the answers

Which autonomic components provide regulatory input to the enteric nervous system?

<p>Parasympathetic and sympathetic neurons (C)</p> Signup and view all the answers

Where do visceral sensory signals from internal organs primarily travel to within the brainstem?

<p>Nucleus of the solitary tract (NST) (D)</p> Signup and view all the answers

What is one of the main functions of the nucleus of the solitary tract (NST)?

<p>Local reflex activity and higher brain integration (B)</p> Signup and view all the answers

What type of neurons are involved in activating preganglionic and postganglionic neurons for reflex activity?

<p>Brainstem reticular formation neurons (D)</p> Signup and view all the answers

What effect does the sympathetic nervous system have on blood flow?

<p>Blood flow is redistributed to striated and cardiac muscle. (C)</p> Signup and view all the answers

Which statement accurately describes the neurotransmitter released by postganglionic parasympathetic neurons?

<p>They exclusively release acetylcholine. (B)</p> Signup and view all the answers

Where are the majority of preganglionic neurons of the parasympathetic nervous system located?

<p>In the visceral efferent motor nuclei of cranial nerves. (D)</p> Signup and view all the answers

What is a characteristic of the postganglionic neurons in the sympathetic nervous system?

<p>They are long and non-myelinated. (D)</p> Signup and view all the answers

Which function is primarily associated with the enteric nervous system?

<p>Controlling gut motility and secretion. (D)</p> Signup and view all the answers

What is the role of the postganglionic neurons in the parasympathetic nervous system?

<p>They are usually found in discrete ganglia close to their targets. (A)</p> Signup and view all the answers

What primary neurotransmitter do most postganglionic sympathetic neurons release?

<p>Noradrenaline (A)</p> Signup and view all the answers

What is the main role of sensory neurons in the myenteric plexus?

<p>To measure the degree of stretch in smooth muscles (D)</p> Signup and view all the answers

How do secretomotor neurons function within the enteric nervous system?

<p>They promote mucous release into the lumen. (A)</p> Signup and view all the answers

Which of the following accurately describes the role of the nucleus of the solitary tract (NST)?

<p>It integrates visceral sensory information for higher brain functions. (A)</p> Signup and view all the answers

Which neurotransmitter is NOT typically used in the enteric nervous system?

<p>Norepinephrine (C)</p> Signup and view all the answers

What type of neurons primarily relay visceral sensory information to the dorsal root ganglion?

<p>Visceral sensory DRG neurons (C)</p> Signup and view all the answers

Which of the following statements about the enteric nervous system is true?

<p>It operates independently yet receives regulatory input from autonomic neurons. (D)</p> Signup and view all the answers

What is the function of interneurons in the enteric nervous system?

<p>They connect sensory neurons to motor neurons. (C)</p> Signup and view all the answers

Which type of neurons directly innervate the visceral sensory division of the NST?

<p>Visceral sensory neurons from cranial nerves IX and X (B)</p> Signup and view all the answers

What role do adrenergic receptors play in sympathetic targets?

<p>They activate intracellular signaling pathways for slow-acting and prolonged responses. (D)</p> Signup and view all the answers

Which structure primarily houses the cell bodies of preganglionic sympathetic neurons?

<p>Intermediolateral horn (IML) (D)</p> Signup and view all the answers

What are the two main types of acetylcholine receptors found in the autonomic nervous system?

<p>Nicotinic and muscarinic receptors (D)</p> Signup and view all the answers

What axonal characteristics distinguish postganglionic sympathetic neurons?

<p>Short, non-myelinated axons (C)</p> Signup and view all the answers

Where do preganglionic sympathetic axons synapse if they bypass the sympathetic chain?

<p>In prevertebral ganglia (C)</p> Signup and view all the answers

What function does the Myenteric plexus perform in the enteric nervous system?

<p>Controls gut movements like peristalsis (D)</p> Signup and view all the answers

What type of axons are carried by visceral sensory afferents from organs to the spinal cord?

<p>Lightly myelinated axons that carry sensory information (B)</p> Signup and view all the answers

What influences the physiological effects of acetylcholine in the autonomic nervous system?

<p>The type of acetylcholine receptors present on target cells (D)</p> Signup and view all the answers

Flashcards

Autonomic Nervous System

The autonomic nervous system controls involuntary bodily functions like heart rate, digestion, and breathing without conscious control.

Homeostasis

Maintains a stable internal environment for the body, despite external changes.

Sympathetic Nervous System

The 'fight or flight' response prepares the body for stressful situations by increasing heart rate, dilating pupils, and diverting blood to muscles.

Parasympathetic Nervous System

The 'rest and digest' response promotes calm and relaxation by decreasing heart rate, constricting pupils, and directing blood to the digestive system.

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Enteric Nervous System

A collection of nerves embedded in the lining of the digestive tract controlling its activity.

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Preganglionic Neuron

The first neuron in a two-neuron chain that relays signals from the central nervous system to the target organs.

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Postganglionic Neuron

The second neuron in a two-neuron chain that relays signals from the central nervous system to the target organs.

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Norepinephrine (Noradrenaline)

A neurotransmitter released by most postganglionic sympathetic neurons, responsible for stimulating the 'fight or flight' response.

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Enteric Nervous System (ENS)

Nerves in the gut wall that control digestion independently of the brain.

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Myenteric and Submucosal Plexus

The two major nerve networks within the ENS, located in the muscle layer and submucosa.

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Sensory Neurons (Myenteric Plexus)

Specialized nerve cells in the ENS that detect stretching in the gut wall.

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Sensory Neurons (Submucosal Plexus)

Specialized nerve cells in the ENS that monitor the chemical composition of the gut contents.

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Visceromotor Neurons (ENS)

Nerves within the ENS that control muscle movement in the gut, promoting peristaltic waves.

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Secretomotor Neurons (ENS)

Nerves within the ENS that stimulate the release of mucus into the gut lumen.

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Interneurons (ENS)

Nerves within the ENS that connect sensory and motor neurons, facilitating communication.

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Nucleus of the Solitary Tract (NST)

The main sensory hub in the brainstem that receives visceral sensory information from organs.

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Preganglionic sympathetic neurons

Specialized neurons in the intermediolateral horn (IML) of the spinal cord that send axons to synapse with postganglionic neurons in the sympathetic chain or prevertebral ganglia.

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Sympathetic chain (paravertebral ganglia)

A chain of ganglia located along the vertebral column that receives preganglionic axons from the spinal cord.

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Splanchnic nerves

Nerves that carry preganglionic sympathetic axons from the spinal cord to prevertebral ganglia located in the abdomen.

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Submucosal (Meissner's) plexus

A network of neurons located in the submucosa layer of the gut that regulates secretion and blood flow.

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Myenteric (Auerbach's) plexus

A network of neurons located between the layers of smooth muscle in the gut that controls gut movements.

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Nicotinic acetylcholine receptor

A type of acetylcholine receptor that is found in the sympathetic nervous system and is responsible for transmitting signals from preganglionic to postganglionic neurons.

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Muscarinic acetylcholine receptor

A type of acetylcholine receptor that is found in the parasympathetic nervous system and is responsible for transmitting signals from postganglionic neurons to target organs.

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Adrenergic receptor

A type of adrenergic receptor that is found in the sympathetic nervous system and is responsible for mediating the effects of adrenaline and noradrenaline.

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What does the myenteric plexus sense?

The myenteric plexus, located between the muscle layers of the gut, is responsible for detecting stretch in the smooth muscles. This helps regulate gut motility and peristalsis.

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What does the submucosal plexus sense?

The submucosal plexus, found in the submucosa layer of the gut, monitors the chemical composition of the lumen. This helps regulate secretion and absorption.

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How do visceromotor neurons regulate gut movement?

Excitatory and inhibitory visceromotor neurons work together to control peristalsis. Excitatory neurons stimulate muscle contractions, while inhibitory neurons relax the muscles, allowing food to move down the gut.

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What is the function of secretomotor neurons?

Secretomotor neurons stimulate the release of mucus into the lumen. Mucus is essential for lubricating food and protecting the gut lining.

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What is the role of interneurons in the ENS?

Interneurons connect sensory and motor neurons in the ENS. They act like relay stations, transmitting signals between different parts of the network.

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How is the ENS regulated?

The ENS functions largely independently of the brain, but it receives input from the parasympathetic and sympathetic nervous systems. This allows for coordinated control of digestion.

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How does sensory feedback regulate the ANS?

Sensory feedback from the target organs plays a crucial role in regulating autonomic nervous system activity. This allows for fine-tuning of responses based on the physiological state of the organs.

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What is the function of visceral sensory neurons?

Visceral sensory neurons innervate the target tissues of the ANS, transmitting information about organ function to the central nervous system. This is essential for coordinating appropriate responses and maintaining homeostasis.

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Sympathetic Chain Ganglia (Paravertebral Ganglia)

The sympathetic chain ganglia, found along the spinal cord, receive lightly myelinated axons from preganglionic neurons, which travel through the ventral root and white ramus communicans.

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Prevertebral Ganglia

Prevertebral ganglia receive preganglionic axons via splanchnic nerves, bypassing the chain ganglia. These ganglia are associated with controlling organs in the abdomen and pelvis.

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Preganglionic Sympathetic Axons

The axons from preganglionic neurons in the sympathetic nervous system that travel through the white ramus communicans and enter the sympathetic chain ganglia. These axons are lightly myelinated.

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Postganglionic Sympathetic Axons

The axons from postganglionic neurons in the sympathetic nervous system that leave the sympathetic chain ganglia and travel via the gray ramus communicans to innervate target organs.

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Visceral Sensory Afferents

Sensory neurons carrying information from internal organs to the central nervous system, traveling through the dorsal root ganglion.

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Study Notes

Nervous System Organization

  • The autonomic nervous system (ANS) maintains homeostasis, despite external variations.
  • It controls internal body functions without conscious input.

Sympathetic Nervous System

  • Function: Prepares the body for stressful situations ("fight-or-flight").
  • Responses: Increased heart rate, dilated pupils, diverted blood flow away from non-essential organs to muscles, increased respiration, increased glycogen breakdown.
  • Mechanism: Two-neuron relay:
    • Preganglionic neurons are short, lightly myelinated, and release acetylcholine (ACh).
    • Postganglionic neurons are long, non-myelinated and for the most part, release noradrenaline (90% of them); a small percentage of them release ACh.
    • Postganglionic neurons also project to targets like smooth muscle, glands, and cardiac muscles.

Parasympathetic Nervous System

  • Function: Prepares the body for rest and digestion ("rest-and-digest").
  • Responses: Decreased heart rate, constricted pupils, increased digestive functions, slowed respiration.
  • Mechanism: Two-neuron relay:
    • Preganglionic neurons are long, lightly myelinated, and release acetylcholine (ACh).
    • Postganglionic neurons are short, non-myelinated, and release acetylcholine (ACh).
    • Some parasympathetic preganglionic neurons are located in cranial nerves.

Enteric Nervous System (ENS)

  • Function: Regulates the activity of the gastrointestinal (GI) tract, including digestion, secretion, and motility.
  • Location: Embedded in the lining of the gastrointestinal (GI) tract.
  • Relationship to other systems: Largely independent of the brain and spinal cord, but receives input from parasympathetic (vagus nerve) and sympathetic branches.

Sympathetic Nervous System Relay

  • Preganglionic: Short, lightly myelinated axons, releasing acetylcholine (ACh)
  • Postganglionic: Long, non-myelinated axons, mostly releasing noradrenaline (90%) or acetylcholine (10%).

Parasympathetic Nervous System

  • Preganglionic: Long, lightly myelinated axons, releasing acetylcholine (ACh)
  • Postganglionic: Short, non myelinated axons,releasing acetylcholine (ACh).

Autonomic Receptors

  • Adrenergic receptors: Effects of adrenaline/noradrenaline depend on the receptor type, inducing slow-acting and prolonged responses. Effects depend on which G protein they are coupled with. Multiple receptor types mediate acetylcholine's effects.
  • Nicotinic receptors: Found on postganglionic neurons, inducing quick, brief responses.
  • Muscarinic receptors: On target tissues, inducing a prolonged effect.

Autonomic Nervous System Regulation

  • Sensory feedback from target organs influences ANS activity.
  • Visceral sensory neurons send information to the nucleus of the solitary tract (NST) in the medulla.
  • Brainstem and higher brain centers coordinate ANS function for reflex and higher-level control.
  • Central sensory neurons (afferents) from cranial nerves IX and X directly connect to the nucleus of the solitary tract (NST) in the medulla. Visceral sensory neurons from spinal nerves (DRG neurons) indirectly connect to the NST.

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