Nervous System Anatomy

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Questions and Answers

Which term refers specifically to a collection of nerve fibers in the central nervous system?

  • Tract (correct)
  • Nucleus
  • Ganglia
  • Nerve

What term describes the orientation of structures away from the middle of the body?

  • Contralateral
  • Medial
  • Ipsilateral
  • Lateral (correct)

Which type of brain slicing separates the brain into a front and back part?

  • Sagittal slicing
  • Coronal slicing (correct)
  • Transverse slicing
  • Horizontal slicing

Which of the following statements about gray and white matter is correct?

<p>Gray matter contains mostly unmyelinated interneurons. (A)</p> Signup and view all the answers

Which layer of the meninges is described as thick, tough, and flexible but not stretchable?

<p>Dura mater (B)</p> Signup and view all the answers

What is one of the primary functions of the cerebellum?

<p>Integrating sensory information and coordinating motor output (B)</p> Signup and view all the answers

Which structure of the mesencephalon is primarily responsible for auditory functions?

<p>Inferior colliculus (C)</p> Signup and view all the answers

What are the two main components of the diencephalon?

<p>Thalamus and hypothalamus (B)</p> Signup and view all the answers

Which structure in the mesencephalon is involved in pain sensitivity reduction when stimulated?

<p>Periaqueductal gray (C)</p> Signup and view all the answers

Loss of which structure in the brain is primarily associated with Parkinson's disease?

<p>Substantia nigra (B)</p> Signup and view all the answers

Which part of the mesencephalon is responsible for directing the body's orientation towards visual stimuli?

<p>Tectum (A)</p> Signup and view all the answers

Which feature does the thalamus NOT typically possess?

<p>Majority of the brain's neuron population (A)</p> Signup and view all the answers

Which structure is primarily responsible for regulating the autonomic nervous system?

<p>Hypothalamus (D)</p> Signup and view all the answers

What is the primary function of sensory relay nuclei in the thalamus?

<p>Transmitting sensory signals to the cortex (A)</p> Signup and view all the answers

Which part of the brain is involved in complex cognitive processes such as learning and problem solving?

<p>Telencephalon (D)</p> Signup and view all the answers

What is the function of the corpus callosum?

<p>Connecting the cerebral hemispheres (C)</p> Signup and view all the answers

What type of neurons mainly compose the cerebral cortex?

<p>Unmyelinated neurons (D)</p> Signup and view all the answers

Which structure is implicated in the crossing over of optic nerve axons?

<p>Optic chiasm (D)</p> Signup and view all the answers

What are the bulges found between fissures and sulci in the cerebral cortex called?

<p>Gyri (B)</p> Signup and view all the answers

What constitutes the white matter of the brain?

<p>Myelinated axons (D)</p> Signup and view all the answers

Which fissure divides the cerebral hemisphere into frontal and parietal lobes?

<p>Central fissure (D)</p> Signup and view all the answers

What is the primary function of the motor association cortex?

<p>Control of the primary motor cortex (M1) (C)</p> Signup and view all the answers

Which layer organization is typical of the neocortex?

<p>6-layered structure differing in cell body size and density (A)</p> Signup and view all the answers

What role does the hippocampus primarily serve?

<p>Memory for spatial location (B)</p> Signup and view all the answers

Which statement about the prefrontal cortex is accurate?

<p>Damage can lead to impairments in voluntary behavior. (C)</p> Signup and view all the answers

How are the systems of the limbic system and basal ganglia categorized?

<p>For organizational purposes only. (B)</p> Signup and view all the answers

What distinguishes the hippocampus from the neocortex?

<p>Having fewer layers and unique shape. (B)</p> Signup and view all the answers

What distinguishes pyramidal cells from stellate cells in the neocortex?

<p>Pyramidal cells are typically larger and more elongated. (C)</p> Signup and view all the answers

Which of the following accurately describes the relationship between the amygdala and the limbic system?

<p>The amygdala is a component of the limbic system. (A)</p> Signup and view all the answers

What is the primary function of the primary motor cortex (M1)?

<p>Execution of voluntary motor movements. (A)</p> Signup and view all the answers

Which type of brain slice separates the brain into anterior and posterior parts?

<p>Coronal (B)</p> Signup and view all the answers

Which terms refer to the same type of brain slicing?

<p>Frontal and coronal (C)</p> Signup and view all the answers

What type of slice is typically used to represent cross-sections viewed from above?

<p>Axial (B)</p> Signup and view all the answers

What orientation does a cross-section of the spinal cord have compared to the ground?

<p>Perpendicular (C)</p> Signup and view all the answers

Which division of the nervous system regulates the body's internal environment?

<p>Autonomic nervous system (A)</p> Signup and view all the answers

Which statement about cranial nerves is accurate?

<p>The vagus nerve is one of the cranial nerves. (A)</p> Signup and view all the answers

Which combination presents a mistake in the order of the brain's protective layers?

<p>Subarachnoid space, pia mater, dura mater (A)</p> Signup and view all the answers

The blood-brain barrier is best described as:

<p>A thickening of cerebral blood vessel walls. (B)</p> Signup and view all the answers

In terms of spinal cord anatomy, which is accurate about the roots?

<p>The dorsal root contains sensory neurons; ventral contains motor neurons. (C)</p> Signup and view all the answers

Which two structures develop from the hindbrain?

<p>Myelencephalon + metencephalon (C)</p> Signup and view all the answers

The forebrain consists of which two main components?

<p>Telencephalon + diencephalon (C)</p> Signup and view all the answers

Which division of the brain contains no reticular nuclei?

<p>Diencephalon (B)</p> Signup and view all the answers

The cerebellum develops from which structure?

<p>Metencephalon (A)</p> Signup and view all the answers

The tectum represents which surface of the midbrain?

<p>Dorsal (B)</p> Signup and view all the answers

The inferior and superior colliculi are part of which structure?

<p>Tectum (C)</p> Signup and view all the answers

Where is the substantia nigra located in relation to the periaqueductal gray?

<p>Ventral (C)</p> Signup and view all the answers

The thalamic lobes are found on which sides of the third ventricle?

<p>Medial (A)</p> Signup and view all the answers

What primarily composes the cerebral cortex?

<p>Small unmyelinated neurons (D)</p> Signup and view all the answers

In which part of the brain is the primary visual cortex located?

<p>Dorsal part of the occipital lobe (A)</p> Signup and view all the answers

Which axis is followed when traveling through the brain areas: Forebrain - Midbrain - Hindbrain?

<p>Anterior - posterior (D)</p> Signup and view all the answers

What is the role of the sympathetic nervous system in relation to blood flow during stress?

<p>Reduces blood flow to the skin (B)</p> Signup and view all the answers

During face recognition, which brain phenomenon is indicated when similar brain areas are active for bird watching and stamp collecting?

<p>Brain lateralization (B)</p> Signup and view all the answers

Which structure is primarily responsible for connecting the limbic system to the hypothalamus?

<p>Fornix (D)</p> Signup and view all the answers

Which sulcus is known as the Sylvian fissure?

<p>Lateral sulcus (D)</p> Signup and view all the answers

What region lies directly dorsal to the corpus callosum?

<p>Cingulate cortex (C)</p> Signup and view all the answers

When comparing nuclei A and B in a coyote's brain, which directional term is most accurate for nucleus A relative to B?

<p>Rostral (C)</p> Signup and view all the answers

What might be the implication of separate counting in different sensory tasks, as indicated by specific areas in the brain being active during diverse activities?

<p>Functional compartmentalization (D)</p> Signup and view all the answers

Which structure forms the lateral boundary of the third ventricle?

<p>Thalamus (B)</p> Signup and view all the answers

Who is credited with defining brain structures as part of detailed anatomical observations?

<p>Santiago Ramón y Cajal (B)</p> Signup and view all the answers

Which of the following is incorrectly matched with its location?

<p>Cingulate cortex - inferior parietal gyrus (D)</p> Signup and view all the answers

What structure is located ventrally to the thalamus?

<p>Hypothalamus (B)</p> Signup and view all the answers

How does the central sulcus function as a boundary in the brain?

<p>Distinguishes the frontal lobe from the parietal lobe (C)</p> Signup and view all the answers

Which brain structure is primarily involved in emotional responses and memory?

<p>Amygdala (B)</p> Signup and view all the answers

What distinguishes the coronal section of the brain from other types of slicing?

<p>It separates the brain into front and back parts (D)</p> Signup and view all the answers

Which part of the brain is involved in language production?

<p>Broca's area (B)</p> Signup and view all the answers

What role do sensory relay nuclei in the thalamus primarily serve?

<p>Routing sensory information to the cortex (C)</p> Signup and view all the answers

Which of the following pairs correctly identifies the positioning of the amygdala in relation to other structures?

<p>Lateral to the thalamus (D)</p> Signup and view all the answers

Which brain structure acts as a bridge between the limbic structures and the basal ganglia?

<p>Globus pallidus (A)</p> Signup and view all the answers

Where is the primary motor cortex located in relation to the central sulcus?

<p>Anterior (C)</p> Signup and view all the answers

Flashcards

Nerve

A bundle of nerve fibers (axons) located in the peripheral nervous system, extending throughout the body.

Tract

A group of nerve fibers (axons) within the central nervous system.

Gray matter

Regions within the central nervous system primarily composed of cell bodies and unmyelinated interneurons, involved in information processing.

White matter

Regions within the central nervous system mostly made up of myelinated axons, responsible for quick signal transmission.

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Dura mater

A tough, flexible membrane that covers the brain and spinal cord, providing protection. It is the outermost layer of the meninges.

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What is the cerebellum's role?

The cerebellum is a brain structure responsible for coordinating movements, motor control, and some cognitive functions like learning.

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How does the cerebellum coordinate movement?

The cerebellum receives information from several senses (vision, hearing, touch, and body position) and integrates it with information about planned movements from the brain. This processed information helps fine-tune and coordinate movements.

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What is the mesencephalon?

The mesencephalon or midbrain is a crucial part of the brain stem, involved in sensory processing, movement control, and wakefulness.

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What is the tectum?

The tectum is the dorsal part of the midbrain responsible for processing auditory and visual information. It plays a key role in orienting the body towards or away from stimuli.

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What is the tegmentum?

The tegmentum is the ventral part of the midbrain containing important structures like the reticular formation and tracts that connect different brain regions.

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What is the thalamus?

The thalamus is a relay center for sensory information, filtering and passing it on to the cerebral cortex, the outer layer of the brain where higher-order processing occurs.

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What is the hypothalamus?

The hypothalamus is a small but important brain structure that regulates basic bodily functions like hunger, thirst, temperature, and hormone release, playing a vital role in maintaining homeostasis.

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Sensory relay nuclei

A group of nuclei in the thalamus that receive sensory signals from specific receptors, process the signals, and then transmit them to the relevant areas of the cerebral cortex. They also receive feedback from the cortex to control which sensory information is processed.

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Thalamus

The main relay station for sensory information, receiving most neural input from the body and sending it to the cerebral cortex.

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Hypothalamus

Located below the anterior thalamus, it plays a crucial role in regulating the body's internal environment, including functions like feeding, drinking, sleep, and body temperature.

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Pituitary Gland

A gland located beneath the hypothalamus that releases hormones to regulate various bodily functions.

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Optic Chiasm

The point where the optic nerves from each eye meet and some of the axons cross over to the opposite side of the brain.

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Mamillary bodies

A pair of rounded nuclei located at the inferior surface of the hypothalamus, involved in memory and other functions.

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Cerebral Cortex (Gray Matter)

The outermost layer of the cerebral cortex, mainly composed of small, unmyelinated neurons, responsible for higher cognitive functions.

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Convolutions of the Cerebral Cortex

The intricate folds and furrows on the surface of the cerebral cortex. These convolutions increase the surface area of the cortex, allowing for greater processing power.

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Premotor Cortex

A brain region just rostral to M1, responsible for controlling M1 and involved in complex motor planning.

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Prefrontal Cortex

The most anterior part of the frontal lobe, crucial for executive functions like planning, reasoning, and judgment.

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Prefrontal Cortex Damage

Impairment in initiating voluntary behavior, difficulty inhibiting inappropriate social behavior, and memory dysfunction due to damage to the prefrontal cortex.

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Neocortex

The neocortex is the 6-layered layout of the cerebral cortex, responsible for higher cognitive functions.

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Neocortical Columnar Organization

This refers to the organization of neurons in the neocortex, forming vertical columns, each performing a specific function.

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Hippocampus

A three-layered brain region crucial for memory, especially spatial memory. It is located in the medial temporal lobe.

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Limbic System

A collection of brain structures involved in emotion, motivation, and memory. Key components include the amygdala and hippocampus.

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Amygdala

An almond-shaped brain structure in the temporal lobe, crucial for processing emotions, especially fear.

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Basal Ganglia

A set of brain structures deep within the cerebrum, involved in motor control, learning, and planning.

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Coronal Slice

A view of the brain from the front, showing the face and the back of the head.

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Horizontal Slice

A view of the brain from the top, looking down on the brain.

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Sagittal Slice

A view of the brain from the side, showing the ears and the back of the head.

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Axial Slice

A view of the brain from the top, looking down on the brain.

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Autonomic Nervous System

Part of the nervous system that controls involuntary bodily functions.

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Cranial Nerves

A set of 12 nerves that connect the brain to the head and neck.

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Subarachnoid Space

A fluid-filled space between the arachnoid membrane and pia mater, containing cerebrospinal fluid.

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Blood-Brain Barrier

A network of blood vessels that supplies the brain with nutrients and oxygen.

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Dorsal Root

The part of the spinal cord that carries sensory information to the brain.

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What does the hindbrain develop into?

The myelencephalon (medulla) and metencephalon (pons and cerebellum) together make up the hindbrain.

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What does the forebrain develop into?

The telencephalon (cerebral hemispheres) and diencephalon (thalamus and hypothalamus) form the forebrain.

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Where is the reticular formation NOT found?

The reticular formation, a network of neurons involved in arousal and sleep-wake cycles, is present in the mesencephalon (midbrain), myelencephalon (medulla), and metencephalon (pons), but not the diencephalon.

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Which brain region includes the Cerebellum?

The cerebellum is part of the metencephalon, which also includes the pons.

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Where is the tectum located?

The tectum is the dorsal surface of the mesencephalon (midbrain).

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Where are the colliculi located?

The inferior and superior colliculi, involved in auditory and visual processing, are located in the tectum of the midbrain.

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Where is the substantia nigra located?

The substantia nigra, a brain region associated with motor control, is located ventral to the periaqueductal gray, a region involved in pain processing.

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Where is the reticular formation located in the mesencephalon?

The reticular formation, a part of which is found in the mesencephalon, is located dorsal to the red nucleus, a region involved in motor control.

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Where are the thalamic lobes located?

The two thalamic lobes are on each side of the third ventricle, a fluid-filled space within the brain.

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Where is the hypothalamus located?

The hypothalamus, responsible for regulating many bodily functions, is located just inferior to the anterior thalamus.

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What are the three main axes of the brain?

The anterior-posterior axis refers to the direction from the front to the back of the brain. The inferior-superior axis refers to the direction from the bottom to the top of the brain. The lateral-medial axis refers to the direction from the side to the middle of the brain.

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What are the main sulci and gyri that define the lobes of the brain?

The lateral sulcus, also known as the Sylvian fissure, separates the temporal lobe from the frontal and parietal lobes. The central sulcus divides the frontal lobe from the parietal lobe, with the precentral gyrus located in front of it and the postcentral gyrus behind it.

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How does the sympathetic nervous system affect blood flow to the genitalia and gut?

The sympathetic nervous system, part of the autonomic nervous system, is responsible for the 'fight-or-flight' response. It prepares the body for stressful situations by increasing heart rate, blood pressure, and blood flow to muscles. In the case of the genitalia and gut, the sympathetic system has an inhibitory effect, slowing down blood flow.

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What is brain plasticity?

Brain plasticity refers to the brain's ability to change and adapt its structure and function over time in response to experiences. This includes changes in the connections between neurons, the ability to learn new skills, and the ability to recover from brain injury.

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In the image, relative to nucleus B, what is the location of nucleus A?

A coronal section divides the brain into front (anterior) and back (posterior) portions. Therefore, nucleus A is more dorsal and lateral relative to nucleus B in this picture.

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What is the role of the thalamus in sensory processing?

The thalamus is a central relay station for sensory information, receiving input from the body and sending it to the appropriate areas of the cerebral cortex. This filtering and relaying of information allows the brain to process sensory information efficiently and selectively.

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What is the role of the premotor cortex in motor control?

The premotor cortex is a key area for planning and coordinating complex movements. It is located just in front of the primary motor cortex (M1). It receives input from various brain areas, including the prefrontal cortex, and sends signals to M1 to initiate and control movements.

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What is the role of the prefrontal cortex in cognition?

The prefrontal cortex, the most anterior part of the frontal lobe, is responsible for higher-level cognitive functions such as planning, decision-making, working memory, and complex social behaviors. It plays a crucial role in our ability to inhibit impulsive behaviors and to manage emotions.

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What is the role of the hippocampus in memory?

The hippocampus, located in the medial temporal lobe, is essential for memory, particularly spatial memory. It plays a crucial role in forming new memories and retrieving existing ones.

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What is the role of the amygdala in emotion?

The amygdala, located in the temporal lobe, is a key structure for processing emotions, especially fear and anxiety. It receives sensory input and quickly assesses the potential threat level of a situation, triggering appropriate responses.

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Where is the primary auditory cortex?

The primary auditory cortex is located on the superior temporal gyrus, a prominent brain region involved in processing sound information.

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Which area of the brain is not visible from the side?

The insular cortex is located deep within the brain, hidden from view when looking at a whole brain from the side.

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Order the brain structures from medial to lateral.

The medial-lateral axis of the brain arranges structures from the middle (medial) to the outer side (lateral). The correct order is thalamus, third ventricle, hippocampus, and then the cerebral cortex.

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Where is the amygdala located?

The amygdala, responsible for processing emotions, especially fear, is located within the medial temporal lobe.

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Where is the cingulate cortex located?

The cingulate cortex is situated on the cingulate gyrus, positioned dorsal (towards the top) to the corpus callosum, the bridge connecting the two brain hemispheres.

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What does the fornix connect?

The fornix, a crucial pathway for memory and learning, connects the septum and mammillary bodies with the amygdala and hippocampus.

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Where is the globus pallidus located?

The globus pallidus, a key part of the basal ganglia, is situated between the thalamus and the striatum.

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Where is Broca's area located?

Broca's area, crucial for language production, is located on the inferior frontal gyrus.

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What is the role of the hippocampus?

The hippocampus plays a vital role in memory formation and retrieval, particularly spatial memory, working like a file cabinet for experiences and locations.

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What is the limbic system?

The limbic system acts as the brain's emotional center, composed of structures like the amygdala and hippocampus. It plays a crucial role in emotions, motivations, and memory.

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Study Notes

Nervous System Anatomy

  • The vertebrate nervous system has 2 main divisions:
    • Central Nervous System (CNS): Includes the brain and spinal cord.
    • Peripheral Nervous System (PNS): All parts outside the skull and spine; further divided into:
      • Somatic Nervous System (SNS): Interacts with the environment.
        • Afferent nerves carry sensory signals.
        • Efferent nerves carry motor signals to muscles.
      • Autonomic Nervous System (ANS): Regulates internal environment.
        • Afferent nerves carry sensory signals from organs to CNS.
        • Efferent nerves carry motor signals from CNS to organs, including sympathetic and parasympathetic nerves.
      • Cranial Nerves: 12 pairs that project from the brain's ventral surface. These nerves often have specific functions and disruptions can indicate tumor location.
  • These principles of (para)sympathetic activity generally apply, but there are exceptions based on the specific organ being regulated.

Brain Anatomy and Directions

  • Directions: Used to describe locations in the nervous system.

    • Anterior/rostral: Towards the nose.
    • Posterior/caudal: Towards the tail.
    • Dorsal: Towards the back or top.
    • Ventral: Towards the front or bottom.
    • Medial: Towards the middle.
    • Lateral: Away from the middle.
    • Superior: Higher/upper.
    • Inferior: Lower/bottom.
    • Proximal: Close to the CNS.
    • Distal: Far from the CNS.
  • Slicing the brain: Used to view brain tissue sections.

    • Coronal: Front and back section.
    • Sagittal: Left and right section.
    • Horizontal/axial: Upper and lower section.

Meninges and Ventricles

  • Meninges: Protective membranes surrounding the brain and spinal cord. (Dura mater, arachnoid membrane, and pia mater).
  • Ventricles: Four internal chambers in the brain that contain cerebrospinal fluid (CSF) and are interconnected.
  • Cerebrospinal fluid (CSF) is produced by choroid plexuses, excess CSF is absorbed into blood-filled spaces (dural sinuses). Too little or too much CSF can cause problems.

Spinal Cord Structure and Function

  • The spinal cord is a long tube-like structure within the vertebral column.
  • Its main functions include:
    • Distributing motor fibers to muscles/glands.
    • Collecting somatosensory information from the body to be transmitted to the brain.

Development-Based Brain Divisions

  • The embryonic CNS initially develops as a fluid-filled tube.
  • The tube then swells into the forebrain, midbrain and hindbrain.
  • These divisions develop further, leading to the adult brain structures, including the telencephalon, diencephalon, mesencephalon, metencephalon and myelencephalon.

Myelencephalon and Metencephalon

  • These regions of the brain stem are largely composed of tracts carrying signals between the brain and body.
  • The reticular formation is important for sleep, attention, muscle tone, arousal, and reflexes.
  • The cerebellum is responsible for coordinating and smoothing movements, and plays roles in other cognitive tasks like learning.

Mesencephalon

  • The mesencephalon includes the tectum and tegmentum, with different roles, including vision and hearing.
    • Tectum (superior and inferior colliculi) has functions in vision and hearing.
    • Tegmentum has important tracts in the sensorimotor system, as well as parts of the reticular formation, and structures like the substantia nigra and red nucleus.

Diencephalon

  • Comprised of the thalamus and hypothalamus.
  • The thalamus serves as a crucial gateway to the cerebral cortex, processing and relaying sensory information, and receiving feedback from the cortex.
  • The hypothalamus regulates autonomic functions, endocrine system controls, and some motivated behaviors; it is connected to the pituitary gland.

Telencephalon

  • The telencephalon, largely the cerebral hemispheres, has complex functions including:
    • Voluntary movement initiation.
    • Sensory input interpretation
    • Complex cognitive processes.
    • Includes subcortical regions like the basal ganglia and limbic system.

Functional Areas

  • Broca's Area: Associated with speech production, located in the inferior frontal gyrus.
  • Wernicke's Area: Associated with language comprehension, located near the junction of the temporal and parietal lobes.
  • Sensory Cortex: Processes sensory input, including visual, auditory, and somatosensory information, located in different places across the brain.
  • Motor Cortex: Controls voluntary movements, located in the precentral gyrus.
  • Association Cortex: Integrates information from different sensory systems and other areas, involved in higher-level functions, including the prefrontal cortex for planning and reasoning. Association cortices exist for each of the major sensory areas.
  • Limbic System: Network of structures that play a role in emotion, memory, and motivation. Includes the amygdala, hippocampus, cingulate gyrus, and others.
  • Basal Ganglia: Groups of structures important for motor control and aspects of cognition. Includes the caudate nucleus, putamen, and globus pallidus.

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