Nephrotic Syndrome and Renal Pathophysiology

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10 Questions

What is the approximate incidence of thromboembolic events in children?

2-5%

What is a potential risk factor for cardiovascular diseases in children with nephrotic syndrome?

Hyperlipidemia

What is the prognosis for children with steroid-resistant nephrotic syndrome?

They will develop progressive renal insufficiency

What is a recommended approach to managing children with steroid-responsive nephrotic syndrome?

Encouraging normal childhood activities

What is a complication of nephrotic syndrome that is particularly rare in children?

Myocardial infarction

What is the significance of responding to steroid therapy rapidly and having no relapse during the first 6 months after diagnosis?

It is associated with an infrequently relapsing course

What should be avoided in the management of children with nephrotic syndrome?

Aggressive diuresis

What is the heritability of steroid-responsive nephrotic syndrome?

It is rarely hereditary

What is the impact of prolonged cyclophosphamide therapy on fertility in children with nephrotic syndrome?

It decreases fertility

What is the prognosis for children with steroid-responsive nephrotic syndrome in terms of chronic renal failure?

They will not develop chronic renal failure

This quiz explores the pathophysiological mechanisms underlying nephrotic syndrome, including the role of antidiuretic hormone and changes in intravascular volume.

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