Nephron Structure and Function

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Questions and Answers

What is the primary function of the glomerulus?

  • Filtration of blood (correct)
  • Reabsorption of glucose
  • Concentration of urine
  • Transport of urine to the renal pelvis

Which component of the nephron is responsible for the reabsorption of water and sodium under the influence of hormones?

  • Collecting Duct
  • Henle's Loop
  • Distal Convoluted Tubule (correct)
  • Proximal Convoluted Tubule

What structure directly collects glomerular filtrate after it exits the glomerulus?

  • Renal Tubule
  • Collecting Tubule
  • Duct of Bellini
  • Bowman's Capsule (correct)

Which part of the nephron is primarily responsible for glucose reabsorption?

<p>Proximal Convoluted Tubule (B)</p> Signup and view all the answers

How does the structure of the afferent arteriole compare to the efferent arteriole regarding their diameters?

<p>The afferent arteriole is wider (A)</p> Signup and view all the answers

Which function is associated with Henle's Loop?

<p>Reabsorption of water and bicarbonate (A)</p> Signup and view all the answers

What is the final structure that collects urine from the collecting tubules?

<p>Duct of Bellini (C)</p> Signup and view all the answers

What type of cells line the collecting tubule?

<p>Cuboidal epithelial cells (C)</p> Signup and view all the answers

Flashcards

Nephron

The functional unit of the kidney, responsible for filtering blood and forming urine.

Glomerulus

A tuft of capillaries in the nephron that acts as a filter, forcing water and small solutes into Bowman's capsule.

Afferent Arteriole

The blood vessel carrying blood to the glomerulus.

Efferent Arteriole

The blood vessel carrying blood away from the glomerulus.

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Bowman's Capsule

The cup-shaped structure that surrounds the glomerulus and collects the filtered fluid (glomerular filtrate).

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Proximal Convoluted Tubule (PCT)

The initial coiled region of the renal tubule, highly specialized for reabsorption of essential substances.

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Henle's Loop

The U-shaped loop of the renal tubule, critical for water and salt reabsorption.

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Distal Convoluted Tubule (DCT)

The highly convoluted region of the renal tubule, involved in fine-tuning water and electrolyte reabsorption.

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Collecting Duct (Duct of Bellini)

The final part of the nephron, where urine is collected and transported to the renal pelvis for excretion.

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Glomerular Filtrate

The fluid that has been filtered from the blood in the glomerulus.

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Study Notes

Nephron Structure and Function

  • Glomerulus:

    • Acts as an ultrafilter, filtering non-colloidal matter from plasma
    • High blood pressure facilitates filtration
    • High pressure difference between afferent and efferent arterioles
    • Arrangement of short, wide afferent and long, narrow efferent arterioles
  • Bowman's Capsule:

    • Collects the glomerular filtrate
    • Passes to renal tubule
  • Renal Tubule:

    • Starts at Bowman's capsule
    • Divided into four regions:
      • Proximal Convoluted Tubule (PCT):
        • Located in the cortex
        • Highly coiled
        • Brush border for reabsorption
        • Reabsorbs glucose, amino acids, water, NaCl, phosphate, and sulphate
      • Henle's Loop:
        • Descends into the medulla in a U-shape
        • Four segments: descending thick segment, descending thin segment, ascending thin segment, ascending thick segment
        • Reabsorbs water, and rest of glucose and bicarbonate
      • Distal Convoluted Tubule (DCT):
        • Located in the cortex
        • Coiled
        • Reabsorbs water under influence of ADH and aldosterone hormone
        • Synthesizes NH3, H+
      • Collecting Tubule/Collecting Duct:
        • Collects urine and concentrates it
        • Reabsorbs water and concentrates urine
        • Sends urine to the duct of Bellini
        • Opens at the apex of the kidney pyramids to the renal pelvis
  • Collecting Duct:

    • Receives urine from collecting tubules
    • Reaches the renal pelvis

Nephron Function in Urine Formation

  • Filtration:
    • Glomerulus filters the blood in the nephron

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