Neoplasia of the Chest in Veterinary Oncology

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Questions and Answers

What is a common presenting symptom in cases of neoplasia of the chest?

  • Weight loss (correct)
  • Decreased respiratory rate
  • Normal heart sounds
  • Increased appetite

Which diagnostic technique is commonly used to differentiate between lymphoma and thymoma?

  • X-ray imaging
  • Ultrasound guided aspirate (correct)
  • Blood test
  • CT scan

What is the median survival time for cats diagnosed with thymoma?

  • 76 days
  • 1825 days (correct)
  • 365 days
  • 635 days

What is the typical prognosis after surgery for hemangiosarcoma?

<p>3-6 months (B)</p> Signup and view all the answers

Which of the following is a paraneoplastic sign associated with neoplasia of the chest?

<p>Jugular venous distension (C)</p> Signup and view all the answers

Which approach to the thorax is NOT mentioned as a surgical option for chest neoplasia?

<p>Chest tube placement (B)</p> Signup and view all the answers

Which imaging technique is NOT typically utilized to diagnose cardiac issues?

<p>Magnetic resonance imaging (A)</p> Signup and view all the answers

What is a common differential diagnosis for neoplastic hemorrhagic effusion?

<p>Idiopathic hemorrhagic effusion (B)</p> Signup and view all the answers

What percentage of dogs diagnosed with thymoma underwent surgery?

<p>72% (A)</p> Signup and view all the answers

Which of the following is a surgical approach used for chest wall tumors?

<p>Chest wall resection (C)</p> Signup and view all the answers

Which of the following instruments is typically NOT used in thoracic surgery?

<p>Ultrasound machine (B)</p> Signup and view all the answers

What is the recurrence rate for osteosarcoma after chemotherapy as reported?

<p>12% (C)</p> Signup and view all the answers

Which breed is most commonly associated with thymoma?

<p>Labrador Retriever (D)</p> Signup and view all the answers

Flashcards

Hemangiosarcoma (HSA)

Cancers originating from blood vessels, often found in cardiac or splenic regions.

Pericardectomy

Surgical removal of the pericardium, the sac surrounding the heart. Often performed for conditions like pericardial effusion.

Microscopic Instruments

The use of specialized surgical instruments designed for precise work in delicate areas, like the heart.

Chest Wall Resection

Surgical procedure involving the removal of a portion of the chest wall (bones and tissue), often used to treat tumors or injuries.

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Deep Pectoral Muscle

A specific muscle found in the chest used to help cover defects during chest wall resection.

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Coughing

A common presentation of chest neoplasia in dogs. It can be caused by respiratory distress, lung compression or mass effect.

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Myasthenia Gravis

A condition commonly associated with thymoma in dogs, characterized by muscle weakness and fatigue.

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Thymoma

A type of chest tumor that can cause respiratory distress, heart problems and even neurologic signs.

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Thoracic Surgery

A procedure used to remove a tumor located in the chest, often performed through a cut in the chest wall.

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Pericardial Effusion

A common complication of thymoma, which can result in cardiac tamponade and reduced heart function.

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Median Sternotomy

A surgical procedure to remove a tumor in the chest, done by making a cut along the midline of the chest.

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Ultrasound

An imaging technique that uses sound waves to visualize the internal organs and structures, often used to diagnose and monitor chest tumors.

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Flow Cytometry

A blood test that can be used to diagnose thymoma and determine its stage

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Study Notes

Neoplasia of the Chest

  • Nick Bacon is a specialist in surgical oncology, clinical director at AURA Veterinary, and professor of surgical oncology at the University of Surrey.
  • He has several veterinary certifications including MA VetMB, CertVR, CertSAS, DiplECVS, DACVS, and FRCVS.
  • He is a founding fellow of the ACVS (American College of Veterinary Surgeons) and a RCVS specialist in surgical oncology.

Conflict of Interest

  • The presenter has no relevant financial interests, arrangements, or affiliations with any organization or business entity that could be perceived as a conflict of interest or bias in the context of the presentation.

Plan

  • The plan includes reviewing neoplastic conditions, diagnostic imaging, procedure details (requirements and risks), and prognosis.

Tissues Affected

  • The affected tissues include the thymus, heart, lymph nodes, esophagus, trachea, and chest wall.

Typical Patient History

  • Symptoms often include weight loss, cough, lethargy, tachypnea (rapid breathing), inappetence (loss of appetite), increased respiratory effort (sometimes), collapse, and chest wall mass.

Physical Examination

  • Physical examination may reveal decreased lung sounds, muffled heart sounds, jugular venous distension, and head and neck distension.

Ascites and Pleural Effusion

  • Ascites and pleural effusion are possible findings.

Paraneoplastic Signs

  • Possible paraneoplastic signs include mega-esophagus, exfoliative dermatitis, and hypercalcaemia.

Cranial Mediastinal Mass Differential Diagnoses

  • Potential diagnoses include thymoma, lymphoma, ectopic thyroid, rib mass extension, and branchial cyst.

Diagnosis

  • Diagnosis often involves ultrasound-guided aspirate, flow cytometry, and/or ultrasound-guided Tru-cut biopsy.

Approaches to Thorax

  • Surgical approaches include lateral/intercostal thoracotomy, median sternotomy, and thoracoscopy.

Instruments

  • Instruments can include oscillating/sagittal saws, mini-drivers, and Finochietto rib retractors.

Malleable Retractors

  • Malleable retractors are used to expose and manipulate tissues during surgery. The right auricular appendage is sometimes a visible landmark.

Satinsky Vascular Clamps

  • Satinsky vascular clamps are used for blood vessel control.

Thymoma

  • 38% of cases are in Labradors or Golden Retrievers.

  • 17% have myasthenia gravis.

  • 34% have hypercalcaemia.

  • 27% have another tumour.

  • 72% undergo surgery.

  • Median survival time for dogs with surgery is 635 days.

  • Dogs without surgery have a median survival time of 76 days.

  • In cats, Median survival with thymoma is 825 days and 1-year and 3-year survival rates are 89% and 74% respectively.

Pericardial Effusion

  • Possible diagnoses include idiopathic hemorrhagic effusion and neoplastic hemorrhagic effusion.
  • Investigation may include cardiac ultrasound and staging.
  • Treatment often includes pericardectomy, and excision of the right auricle.

Haemangiosarcoma

  • This is a condition.

Teflon Stents

  • Teflon stents are used during procedures to treat issues like haemangiosarcoma.

OSA/Primary Rib Tumors

  • Median survival times for dogs with OSA with 290 for 19/23 chemo and 119d for 13 cases.
  • Recurrence rates are 12% with chemo and 0% without.
  • Metastasis rates are 75% with chemo and 38% without.
  • 34 OSA were treated and followed for a further period (DFI 225d (chemo) vs 60d (no chemo)).

Chest Wall Resections

  • Steps involve cutting skin, resecting muscle and bone, further dissecting muscle to cover defects, closing skin, and inserting chest drains.
  • Average recovery time is 2-5 days post-surgery.

Deep Pectoral Muscle

  • The deep pectoral muscle is a type V muscle with a lateral thoracic blood vessel supply.

What We've Covered

  • Key topics were reviewed, including types of diseases, successful imaging techniques, suitable instruments, surgical approaches, and the prognosis.

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