Neoplasia Lecture 39

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What is the primary characteristic of neoplasia?

Abnormal proliferation of cells that is useful to the body

Abnormal proliferation of cells that is spontaneous and irreversible (correct)

Abnormal proliferation of cells that is stimulated by external factors

Abnormal proliferation of cells that is controlled by the body

What is the main difference between benign and malignant tumors?

Benign tumors are not capsulated and malignant tumors are capsulated

Benign tumors are well-circumscribed and malignant tumors are infiltrative (correct)

Benign tumors are large and malignant tumors are small

Benign tumors are slow-growing and malignant tumors are fast-growing

What is the suffix commonly added to benign tumors?

-algia

-itis

-osis

-oma (correct)

What is the term for malignant tumors of epithelial tissues?

Carcinoma Signup and view all the answers

What is the characteristic of the shape of benign tumors?

Well-circumscribed Signup and view all the answers

What is the characteristic of the size of benign tumors?

Usually small but can be large Signup and view all the answers

What is the characteristic of the capsule of benign tumors?

Usually present but not always Signup and view all the answers

What is the term for malignant tumors of mesenchymal tissues?

Sarcoma Signup and view all the answers

What is a characteristic of benign tumors in terms of their cut surface?

They are usually solid but may be cystic Signup and view all the answers

What is a rare occurrence in benign tumors?

Ulceration Signup and view all the answers

What is a characteristic of benign tumors in terms of their microscopic picture?

The cells are usually small and of equal size and similar shape Signup and view all the answers

What is a characteristic of malignant tumors in terms of their size?

They usually reach a large size in a short time Signup and view all the answers

What is a characteristic of malignant tumors in terms of their shape on body surfaces?

They are usually polypoid, ulcerative, or infiltrating Signup and view all the answers

Why do malignant tumors often lack a capsule?

Due to the rapid rate of growth, the tumor has no time to form a capsule Signup and view all the answers

What is a characteristic of malignant tumors in terms of their microscopic picture?

They show a loss of differentiation Signup and view all the answers

What is a characteristic of malignant tumors in terms of their margins?

They are blurred Signup and view all the answers

What characterizes pleomorphism in cellular morphology?

Cells are larger than normal and show variation in size and shape Signup and view all the answers

What is the nucleo-cytoplasmic (N/C) ratio in malignant cells typically like?

Increased Signup and view all the answers

What abnormality is frequently observed in the nuclei of malignant cells?

Hyperchromatic, enlarged and darkly stained, variable in size, shape and position Signup and view all the answers

Which phenomenon results in a 'tumor giant cell'?

Repeating nuclear division without cytoplasm division Signup and view all the answers

What is a significant characteristic of mitotic figures in malignant tumors?

Frequent and abnormal Signup and view all the answers

What defines the loss of polarity in malignant tumors?

Loss of the normal relation between each cell and the neighboring ones and surrounding tissues Signup and view all the answers