Neoplasia and Tumor Definition Quiz

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Questions and Answers

What is a characteristic feature of tumor cells related to their replicative potential?

  • Enhanced response to apoptosis
  • Increased sensitivity to growth-inhibitory signals
  • Limited replicative potential
  • Unrestricted proliferative capacity (correct)

What is a mechanism by which tumors evade programmed cell death?

  • Increased sensitivity to growth-inhibitory signals
  • Inactivation of p53 (correct)
  • Activation of anti-angiogenesis genes
  • Enhanced response to apoptosis signals

What process do tumors rely on for the formation of a vascular supply?

  • Apoptosis
  • Senescence
  • Mitotic catastrophe
  • Angiogenesis (correct)

What is a common defect in tumors related to DNA repair?

<p>Failure to repair DNA damage (D)</p> Signup and view all the answers

What are tumors resistant to in terms of cellular proliferation?

<p>Cyclin-dependent kinases (CDKIs) (A)</p> Signup and view all the answers

What characteristic of tumor metastases leads to the majority of cancer deaths?

<p>Ability to invade and metastasize (A)</p> Signup and view all the answers

Which of the following best defines a neoplasm?

<p>A mass of tissue formed as a result of abnormal, excessive, uncoordinated, autonomous and purposeless proliferation of cells (C)</p> Signup and view all the answers

What is the main characteristic of neoplastic cells?

<p>Loss of control and regulation of replication (D)</p> Signup and view all the answers

How are tumors classified?

<p>Taking into account their morphological structure, localization, and growth patterns (A)</p> Signup and view all the answers

What key change indicates malignancy in tumors?

<p>Capacity to proliferate without external stimuli (C)</p> Signup and view all the answers

What is the role of autonomy in neoplastic growth?

<p>Dependence on the 'feeding' blood vessels and innervation (A)</p> Signup and view all the answers

What process involves new tissue formation due to hormonal stimulation?

<p>Hyperplasia (D)</p> Signup and view all the answers

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