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Neoplasia and Tumor Definition Quiz

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Questions and Answers

What is a characteristic feature of tumor cells related to their replicative potential?

Enhanced response to apoptosis

Increased sensitivity to growth-inhibitory signals

Limited replicative potential

Unrestricted proliferative capacity (correct)

What is a mechanism by which tumors evade programmed cell death?

Increased sensitivity to growth-inhibitory signals

Inactivation of p53 (correct)

Activation of anti-angiogenesis genes

Enhanced response to apoptosis signals

What process do tumors rely on for the formation of a vascular supply?

Apoptosis

Senescence

Mitotic catastrophe

Angiogenesis (correct)

What is a common defect in tumors related to DNA repair?

Failure to repair DNA damage Signup and view all the answers

What are tumors resistant to in terms of cellular proliferation?

Cyclin-dependent kinases (CDKIs) Signup and view all the answers

What characteristic of tumor metastases leads to the majority of cancer deaths?

Ability to invade and metastasize Signup and view all the answers

Which of the following best defines a neoplasm?

A mass of tissue formed as a result of abnormal, excessive, uncoordinated, autonomous and purposeless proliferation of cells Signup and view all the answers

What is the main characteristic of neoplastic cells?

Loss of control and regulation of replication Signup and view all the answers

How are tumors classified?

Taking into account their morphological structure, localization, and growth patterns Signup and view all the answers

What key change indicates malignancy in tumors?

Capacity to proliferate without external stimuli Signup and view all the answers

What is the role of autonomy in neoplastic growth?

Dependence on the 'feeding' blood vessels and innervation Signup and view all the answers

What process involves new tissue formation due to hormonal stimulation?

Hyperplasia Signup and view all the answers