Neonatal Sepsis

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15 Questions

What is a characteristic of neonates that makes them more susceptible to infections?

Immune system immaturity

Which group of neonates is at the highest risk for developing neonatal sepsis?

Preterm newborns with respiratory distress

What is the primary reason why neonates should be considered immunocompromised?

Immature immune system

What is a common complication of neonatal sepsis in preterm newborns?


Why are neonates considered at increased risk for infections?

Due to their immature immune system

What is the typical time frame for the presentation of early-onset neonatal sepsis?

The first 7 days of life

What is the primary source of organisms causing early-onset neonatal sepsis?

Maternal genital tract

What is the most common cause of early-onset neonatal sepsis?

Bacterial infections

When is early-onset neonatal sepsis most likely to occur?

During the first week of life

What is the primary route of transmission for early-onset neonatal sepsis?

Vertical transmission from mother to child

What is the most common temperature instability in neonatal sepsis?


What is a common sign of neonatal sepsis that may also be a manifestation of meningitis?


Which of the following is NOT a sign of neonatal sepsis?


What is a common complication of neonatal sepsis?

Disseminated intravascular coagulation

What is the primary way to diagnose neonatal sepsis?

Clinical manifestations and laboratory tests

Study Notes

Neonatal Sepsis

  • Neonates, especially preterm newborns, are at increased risk for infections and are considered immunocompromised.
  • Early-onset neonatal sepsis (0-7 days) is usually caused by organisms acquired from the maternal genital tract.

Clinical Manifestations of Neonatal Sepsis

  • Common signs of neonatal sepsis include poor feeding, temperature instability, lethargy, and apnea.
  • Hypothermia is more common than fever in neonatal sepsis, especially in preterm newborns.
  • Other signs of neonatal sepsis include tachycardia, dyspnea or cyanosis, tachypnea, disseminated intravascular coagulation (DIC), and abdominal distension.
  • Clinical manifestations of sepsis are difficult to distinguish from those of meningitis in neonates.

Learn about the risks and clinical manifestations of neonatal sepsis, especially in preterm newborns. Understand the causes, signs, and symptoms of this condition.

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