Neonatal Brain Anatomy and Divisions
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Questions and Answers

What is the primary function of the choroid plexus in the brain?

  • Control the body's respiratory functions
  • Produce cerebrospinal fluid (CSF) (correct)
  • Connect the two cerebral hemispheres
  • Regulate blood flow to the brain

Which structure separates the two hemispheres of the brain?

  • Thalamus
  • Falx cerebri (correct)
  • Cerebellum
  • Corpus callosum

At what age does the anterior fontanelle typically close?

  • 2 years (correct)
  • 1 year
  • 6 months
  • 3 years

What connects the lateral ventricles to the third ventricle?

<p>Foramen of Monroe (C)</p> Signup and view all the answers

Which part of the brain is responsible for motor control and coordination?

<p>Cerebellum (C)</p> Signup and view all the answers

What is the most common site of germinal matrix hemorrhage (GMH)?

<p>Caudate nucleus (D)</p> Signup and view all the answers

Which ventricle is located at the midline of the brain?

<p>Third ventricle (A)</p> Signup and view all the answers

Which sutures are found in the human skull?

<p>Coronal and lamboid sutures (C)</p> Signup and view all the answers

What does the caudo-thalamic notch (CTN) refer to?

<p>A groove where two brain structures meet (D)</p> Signup and view all the answers

In which age group of infants is the cavum septum pellucidum (CSP) more cystic?

<p>Newborns and younger infants (B)</p> Signup and view all the answers

Which type of hemorrhage is most commonly associated with the germinal matrix?

<p>Subependymal hemorrhage (B)</p> Signup and view all the answers

What can be observed in a Grade II hemorrhage imaging?

<p>Clot extending into the occipital horn (C)</p> Signup and view all the answers

Which structure is NOT typically seen in midline sagittal imaging of the neonatal brain?

<p>Frontal horn (D)</p> Signup and view all the answers

What is the significance of echogenicity in a hematoma over time?

<p>Echogenicity decreases as the hematoma ages (C)</p> Signup and view all the answers

Which structure(s) is/are classified as lateral structures during neonatal brain assessment?

<p>Thalamus and caudate nucleus (A)</p> Signup and view all the answers

What does the 'lady in the dress' sign refer to in neonatal imaging?

<p>Visualization of certain midline echogenic structures (B)</p> Signup and view all the answers

Flashcards

Neonatal Brain Follow-up

Monitoring a baby's brain after a hydrocephalus diagnosis or prenatal abnormality, or brain injury.

Intercranial Hemorrhage

Bleeding inside the baby's skull.

Anterior Fontanelle

The most common "soft spot" on a baby's head, closed by about 2 years

Posterior Fontanelle

Baby's soft spot open to about 3 months of age

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Cerebral Ventricles

Fluid-filled spaces inside the brain, containing cerebrospinal fluid (CSF).

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Corpus Callosum

A large bundle of nerve fibers connecting the brain's two halves.

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Choroid Plexus

Part of the brain that produces cerebrospinal fluid (CSF).

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Lateral Ventricles

Two large, fluid-filled spaces in the brain, parts of the ventricular system, divided into parts

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Caudo-thalamic Notch (CTN)

The groove or junction where the caudate nucleus and thalamus meet in the neonatal brain.

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Cavum Septum Pellucidum (CSP)

A fluid-filled space between the two halves of the septum pellucidum, a thin membrane separating the lateral ventricles.

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Germinal Matrix Hemorrhage (GMH)

Bleeding in the germinal matrix, an area in the developing brain responsible for cell production.

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Subependymal Hemorrhage (SEH)

A type of GMH where the bleed is confined to the subependymal area, a layer lining the ventricles.

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Intraventricular Hemorrhage (IVH)

A GMH where the blood clot extends into the lateral ventricles.

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Intraparenchymal Hemorrhage (IPH)

A GMH where the blood extends into the brain tissue, typically the frontal or parietal lobes.

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Grade I Hemorrhage

A sub-ependymal hemorrhage confined to the caudo-thalamic notch without significant choroid plexus distortion.

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Grade II Hemorrhage

A hemorrhage that extends from the CTN into the occipital horn of the lateral ventricle.

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Study Notes

Neonatal Brain Anatomy

  • Follow-up: Hydrocephalus or abnormal prenatal diagnoses.
  • Hemorrhage: Intracranial hemorrhage.
  • Fontanelles:
    • Anterior: Most common, open until 2 years (but scans until 12-14 months).
    • Posterior: Open until 3 months, useful for intraventricular hemorrhage and ventricular horns.
  • Sutures: Sagittal, coronal, lambdoid.
  • Falx Cerebri: Fibrous structure separating the two hemispheres.

Brain Divisions

  • Cerebrum: Upper portion, composed of four lobes (frontal, parietal, temporal, occipital).
  • Brain Stem
  • Cerebellum

Ventricles

  • Lateral Ventricles (2): Frontal, body, occipital, and temporal horns. Trigone connects these.
  • Third Ventricle: Midline structure.
  • Fourth Ventricle: Midline structure.
  • Foramen of Monroe: Connects lateral ventricles with third ventricle.
  • Aqueduct of Sylvius: Connects third and fourth ventricles.
  • Foramen of Luschka: Connects fourth ventricle with subarachnoid space.
  • Choroid Plexus (CP): Produces 70% of CSF, located in ventricles. Hyperechoic on sonogram.

Corpus Callosum

  • Deep nerve fiber bridge connecting hemispheres. Superior-medial to lateral ventricles.
  • Hypoechoic, crescent-shape structure.

Thalami

  • Homogenous structure inferior to lateral ventricle bodies.

Cavum Septum Pellucidum (CSP)

  • Hypoechoic structure separating lateral ventricles' frontal horns.
  • Less cystic in older babies.

Caudate Nucleus

  • Relatively hyperechoic structure inferolateral to frontal horn and lateral ventricle body.
  • Meets thalamus at caudothalamic notch (common site for germinal matrix hemorrhage).

Germinal Matrix Hemorrhage (GMH)

  • Types:
    • Sub-ependymal (SEH): Most common.
    • Intraventricular (IVH): Clot enters lateral ventricles.
    • Intraparenchymal (IPH): Hemorrhage enters frontal/parietal lobes.
  • Timing: Most occur in the first 7 days of life.
  • Sonographic appearance:
    • Early: Highly echogenic.
    • Over time: Echogenicity decreases.

Structures on coronal sections

  • Landmarks: Orbits, anterior horn, lateral ventricles, lateral ventricles, corpus callosum, third ventricle, cerebellum, choroid plexus, posterior brain, occipital lobes.

Structures on sagittal sections

  • Midline: Corpus callosum, third ventricle, fourth ventricle, frontal/occipital horns, Aqueduct of Sylvius, Foramen of Monroe.
  • Lateral: Thalamus, germinal matrix (caudothalamic groove), caudate nucleus, choroid plexus, anterior/body/occipital/temporal horns, lateral ventricles, sylvian fissures, temporal lobes.
  • Landmark sign: "Lady in the dress" sign (CP and cerebellar vermis).

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Description

Test your knowledge on the anatomy of the neonatal brain, including critical structures such as fontanelles, sutures, and the ventricular system. This quiz covers the various parts of the brain, including the cerebrum, brain stem, and cerebellum. Understand the importance of these structures in prenatal and postnatal diagnoses.

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