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Neisseria Meningitis and Gonorrheae

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Questions and Answers

What is the only host for meningococci?

Humans

How do meningococci resist phagocytosis by polymorphonuclear leukocytes?

By having a polysaccharide capsule

What are the three virulence factors of meningococci?

Endotoxin (LPS), immunoglobulin A protease, and polysaccharide capsule

What specimen is taken for culture and smear to diagnose meningococcal infection?

Spinal fluid Signup and view all the answers

What is the purpose of nasopharyngeal swab cultures in carrier surveys?

To detect asymptomatic carriers of meningococci Signup and view all the answers

What type of agar is used to culture cerebrospinal fluid (C.S.F.) specimens?

Chocolate agar Signup and view all the answers

What test is used to identify meningococcal polysaccharides?

Latex agglutination or hemagglutination test Signup and view all the answers

What is the role of immunoglobulin A protease in meningococcal pathogenesis?

It helps the bacteria attach to the membrane of the upper respiratory tract Signup and view all the answers

How are meningococci transmitted between humans?

By airborne droplets Signup and view all the answers

What is the significance of Gram-stained smears of the sediment of centrifuged spinal fluid?

They often show typical neisseriae within polymorphonuclear leukocytes or extracellularly Signup and view all the answers