Neisseria Meningitis and Gonorrheae

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Questions and Answers

What is the only host for meningococci?

Humans

How do meningococci resist phagocytosis by polymorphonuclear leukocytes?

By having a polysaccharide capsule

What are the three virulence factors of meningococci?

Endotoxin (LPS), immunoglobulin A protease, and polysaccharide capsule

What specimen is taken for culture and smear to diagnose meningococcal infection?

<p>Spinal fluid</p> Signup and view all the answers

What is the purpose of nasopharyngeal swab cultures in carrier surveys?

<p>To detect asymptomatic carriers of meningococci</p> Signup and view all the answers

What type of agar is used to culture cerebrospinal fluid (C.S.F.) specimens?

<p>Chocolate agar</p> Signup and view all the answers

What test is used to identify meningococcal polysaccharides?

<p>Latex agglutination or hemagglutination test</p> Signup and view all the answers

What is the role of immunoglobulin A protease in meningococcal pathogenesis?

<p>It helps the bacteria attach to the membrane of the upper respiratory tract</p> Signup and view all the answers

How are meningococci transmitted between humans?

<p>By airborne droplets</p> Signup and view all the answers

What is the significance of Gram-stained smears of the sediment of centrifuged spinal fluid?

<p>They often show typical neisseriae within polymorphonuclear leukocytes or extracellularly</p> Signup and view all the answers

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