NCM 107 – Maternal and Child Health Module 2

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Questions and Answers

What is the primary role of progesterone during pregnancy?

  • Stimulates the secretion of gonadotropins
  • Maintains pregnancy (correct)
  • Promotes fetal development
  • Induces labor

Which hormone's drop may lead to premature labor in late pregnancy?

  • Follicle-stimulating hormone (FSH)
  • Progesterone (correct)
  • Luteinizing hormone (LH)
  • Estrogen

Which hormone is secreted by the hypothalamus to initiate the hormonal cascade in the menstrual cycle?

  • Gonadotropin releasing hormone (GnRF) (correct)
  • Luteinizing hormone (LH)
  • Estrogen
  • Progesterone

What effect does estrogen have on blood coagulability?

<p>Increases fibrinogen levels (B)</p> Signup and view all the answers

What initiates uterine contractions as pregnancy approaches term?

<p>Drop in progesterone (D)</p> Signup and view all the answers

Which gland secretes gonadotropins during the menstrual cycle?

<p>Anterior pituitary gland (B)</p> Signup and view all the answers

What is a predicted consequence of a drop in progesterone at term?

<p>Enhanced stimulation of uterine contractions (A)</p> Signup and view all the answers

Which hormone is not directly involved in stimulating uterine contractions before labor?

<p>Follicle-stimulating hormone (FSH) (A)</p> Signup and view all the answers

How does progesterone affect smooth muscle in the uterus?

<p>Relaxes smooth muscle, including the myometrial muscle (C)</p> Signup and view all the answers

What is the primary cause of Lyme disease?

<p>Borrelia burgdorferi (B)</p> Signup and view all the answers

Which of the following signifies the end of the first trimester?

<p>Completion of organogenesis (C)</p> Signup and view all the answers

What can tetracycline and doxycycline cause during pregnancy?

<p>Tooth discoloration in the fetus (A)</p> Signup and view all the answers

At which stage does the lung alveoli begin to mature?

<p>End of 16 weeks (A)</p> Signup and view all the answers

What is characteristic of the erythema chronicum migrans associated with Lyme disease?

<p>It has a clear center (A)</p> Signup and view all the answers

When do the finger and toe nails develop?

<p>End of 16 weeks (D)</p> Signup and view all the answers

What hormone is primarily secreted by the corpus luteum in early pregnancy?

<p>Progesterone (D)</p> Signup and view all the answers

How long does the corpus luteum typically live?

<p>10 to 14 days (B)</p> Signup and view all the answers

What process allows sperm to penetrate the corona radiata?

<p>Capacitation (A)</p> Signup and view all the answers

What is the appearance of the 16-celled stage during embryonic development called?

<p>Morula (D)</p> Signup and view all the answers

Which structure is responsible for releasing the ovum?

<p>Graafian follicle (B)</p> Signup and view all the answers

What occurs to the morula on the 4th day after fertilization?

<p>Enters the uterine cavity (C)</p> Signup and view all the answers

What component surrounds the ovum at fertilization?

<p>Zona pellucida and Corona radiata (A)</p> Signup and view all the answers

Which of the following is NOT part of the ovarian cycle?

<p>Formation of the placenta (A)</p> Signup and view all the answers

What is the average volume of semen released per ejaculation?

<p>2.5 ml (D)</p> Signup and view all the answers

How many spermatozoa are typically contained in an average ejaculation?

<p>50-200M (C)</p> Signup and view all the answers

What hormone is responsible for stimulating the proliferation phase of the menstrual cycle?

<p>Follicle-stimulating hormone (FSH) (B)</p> Signup and view all the answers

Which hormone is secreted by the corpus luteum after ovulation?

<p>Progesterone (A)</p> Signup and view all the answers

What triggers the secretion of FSH?

<p>The follicle-stimulating hormone-releasing factor (B)</p> Signup and view all the answers

During which phase of the menstrual cycle is oestrogen at its lowest?

<p>Days 4 to 5 of the menstrual cycle (C)</p> Signup and view all the answers

What is the function of oestrogen in relation to ovarian follicles?

<p>Stimulates development of primordial follicles into Graafian follicles (C)</p> Signup and view all the answers

What is the role of progesterone during early pregnancy?

<p>Maintains the specialization of the endometrium (A)</p> Signup and view all the answers

What characteristic does cervical mucus have during ovulation?

<p>Thin, clear, and stringy (A)</p> Signup and view all the answers

What condition does luteinizing hormone (LH) primarily influence?

<p>The process of ovulation (B)</p> Signup and view all the answers

What physiological change does progesterone facilitate?

<p>Preparation of the endometrium for implantation (C)</p> Signup and view all the answers

How does follicle-stimulating hormone (FSH) affect cervical mucus?

<p>Makes mucus clear and stretchy (D)</p> Signup and view all the answers

Which teratogenic condition is known to cause severe neurologic damage to the infant?

<p>Cytomegalovirus (A)</p> Signup and view all the answers

What type of congenital defect is a patent ductus arteriosus classified as?

<p>Cardiac defect (C)</p> Signup and view all the answers

Which of the following infections is contraindicated in pregnancy due to potential teratogenic effects?

<p>Live virus vaccines for measles, mumps, and rubella (A)</p> Signup and view all the answers

Which ophthalmic condition can be caused by Cytomegalovirus infection during pregnancy?

<p>Optic atrophy (B)</p> Signup and view all the answers

What is the potential implication of dental candidiasis during pregnancy?

<p>Increased risk of dental caries (C)</p> Signup and view all the answers

What is a potential outcome for infants affected by the Herpes Simplex Virus during pregnancy?

<p>Neurologic conditions (B)</p> Signup and view all the answers

Which of the following is a risk factor for restricted intrauterine growth (SGA)?

<p>Maternal smoking (B)</p> Signup and view all the answers

Which of these infections is transmitted by droplet infection and can affect fetal development?

<p>Cytomegalovirus (D)</p> Signup and view all the answers

What complication can occur if a mother is infected with Chlamydia during pregnancy?

<p>Risk of uterine infection (D)</p> Signup and view all the answers

What is the main concern associated with the transmission of Herpes Simplex Virus to the infant?

<p>Severe neurological impairment (D)</p> Signup and view all the answers

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Study Notes

Prenatal Care

  • Prenatal care includes both maternal and fetal health management during pregnancy.
  • Progesterone relaxes smooth muscles, maintaining pregnancy; a drop may lead to abortion or premature labor.

Menstrual Cycle Hormonal Control

  • Hypothalamus secretes gonadotropin-releasing hormone (GnRF) to regulate pituitary gland's gonadotropin secretion.
  • Anterior Pituitary Gland (APG) secretes:
    • Gonadotropins (Gn): Key for reproductive hormone regulation.
    • Follicle-stimulating hormone (FSH): Stimulates ovarian follicle maturation.
    • Luteinizing hormone (LH): Triggers ovulation and supports corpus luteum function.

Ovarian Cycle

  • Involves follicle development, ovulation, corpus luteum formation, and degeneration over a 4-week period.
  • Estrogen is secreted by ovaries and placenta during pregnancy, influencing cervical mucus, endometrial proliferation, and secondary sex characteristics.

Uterine Cycle

  • The uterine cycle coincides with the ovarian cycle, characterized by cyclic endometrial changes in response to hormonal levels.

Sperm Characteristics

  • Average ejaculation releases about 400 million sperm, which travel through the female reproductive tract using flagella and uterine contractions.
  • Sperm undergo capacitation, changing the plasma membrane to enable binding and penetration of the ovum.

Fetal Development Stages

  • At 5-8 weeks, the fetus measures approximately 2.5 cm, with organogenesis complete; meconium is visible on ultrasound.
  • By the end of 12 weeks, fingers and toes develop, kidneys begin urine production, and limb movement is detectable but not felt by the mother.

Infections and Complications in Pregnancy

  • Cytomegalovirus can cause severe neural and ocular damage to infants.
  • Genital Herpes and Lyme disease (caused by Borrelia burgdorferi) can lead to significant complications; certain antibiotics (like tetracycline) are contraindicated in pregnancy.

Teratogenic Influences

  • Live vaccines for measles, mumps, rubella, and poliomyelitis are contraindicated during pregnancy due to potential fetal transmission risks.

Clinical Observations

  • At 16 weeks, tooth buds form, ossification begins in bones, and lung development progresses with surfactant present in amniotic fluid.

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