Natural Killer Cells Response to Viral Infection

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Questions and Answers

How do HIV particles in the blood affect the efficiency of NK cell activities?

  • Increase their ability to kill virus-infected cells
  • Enhance the secretion of γ-interferon
  • Alter the expression of molecules on NK cell surfaces (correct)
  • Activate T lymphocytes

What is the role of perforins released by NK cells in response to viral infection?

  • Activating B lymphocytes
  • Inducing apoptosis in virus-infected cells (correct)
  • Coating virions with antibodies
  • Enhancing the ability to secrete γ-interferon

What triggers the specific immune response in adaptive immunity against viral infections?

  • Epitopes binding to specific receptors on lymphocytes (correct)
  • Cytokines released by infected cells
  • The presence of perforins in the blood
  • Antibodies coating virions

Where do B lymphocytes develop?

<p>Bone marrow (C)</p> Signup and view all the answers

What is the main function of antibodies synthesized by plasma cells during a viral infection?

<p>Coating both virions and virus-infected cells (A)</p> Signup and view all the answers

How does the epitope-lymphocyte receptor interaction lead to an immune response?

<p>By inducing a cascade that activates lymphocytes (C)</p> Signup and view all the answers

What are the 3 basic biochemical processes involved in virus genome replication?

<p>Replication, Transcription, Translation (A)</p> Signup and view all the answers

Where does genome replication occur in DNA viruses?

<p>Nucleus (C)</p> Signup and view all the answers

What type of genes are transcribed before DNA replication begins in DNA viruses?

<p>Early genes (A)</p> Signup and view all the answers

Which of the following is a function of early proteins in DNA virus replication?

<p>Related to genome replication (B)</p> Signup and view all the answers

Why do some viruses with smaller genomes depend more on the host cell for replication?

<p>Fewer gene products produced (D)</p> Signup and view all the answers

What distinguishes the late genes from the early genes in DNA viruses?

<p>Transcription timing (D)</p> Signup and view all the answers

What is the main characteristic that distinguishes cytotoxic T cells?

<p>Presence of CD8 molecules (D)</p> Signup and view all the answers

How do cytotoxic T cells kill target cells?

<p>By inducing apoptosis (B)</p> Signup and view all the answers

What is one of the outcomes of viral infection related to immunological memory?

<p>Formation of memory cells (B)</p> Signup and view all the answers

How can immunological memory impact the signs and symptoms of a viral disease?

<p>Cause the complete absence of symptoms (D)</p> Signup and view all the answers

What is the consequence of programmed cell death (apoptosis) in virus-infected cells?

<p>Halts the infection's spread to other cells (D)</p> Signup and view all the answers

What factor can influence the severity of disease caused by pathogenic viruses?

<p>Virulence of the virus strain (B)</p> Signup and view all the answers

What is the product of transcription in the context of viral replication?

<p>Late mRNA (B)</p> Signup and view all the answers

Which type of RNA viruses replicate via a complementary (+) strand intermediate?

<p>Viruses with ssRNA genome of (+) polarity (C)</p> Signup and view all the answers

What is the main function of late proteins in viral replication?

<p>Ensure viral genome replication (A)</p> Signup and view all the answers

How do RNA viruses with a single-stranded genome of (+) polarity replicate?

<p>Via a complementary (+) strand intermediate (C)</p> Signup and view all the answers

What is the role of RNA dependent RNA polymerase in RNA virus replication?

<p>Replicating the viral RNA genome (D)</p> Signup and view all the answers

Which type of influenza is considered more virulent in humans based on the text?

<p>H5N1 (C)</p> Signup and view all the answers

What might result from a larger dose of the virus according to the text?

<p>Shorter incubation period (D)</p> Signup and view all the answers

Which statement is true regarding latent viral infections based on the text?

<p>Can be reactivated under certain conditions (C)</p> Signup and view all the answers

What is a characteristic of abortive viral infections according to the text?

<p>Host damage occurs but no progeny virus are produced (B)</p> Signup and view all the answers

Which factor can reactivate a latent viral infection per the text?

<p>A second virus infects the host cell (C)</p> Signup and view all the answers

What characterizes productive viral infections according to the text?

<p>Host cell functions normally during viral replication (D)</p> Signup and view all the answers

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