Odontogenic & Nonodontogenic Cysts
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Questions and Answers

Which type of cyst is essentially the same histologically as squamous epithelial lined cysts?

  • Epithelial rests of Malessez (correct)
  • Glandular odontogenic
  • Dentigerous
  • Gingival cyst of newborn
  • What type of cyst typically appears as a well-circumscribed periapical radiolucency with widening of the PDL space and/or loss of lamina dura?

  • Gingival cyst of newborn
  • Gingival cyst of adult
  • Periapical cyst (correct)
  • Fissural cysts
  • Which type of cyst is a central (within bone) lesion?

  • Lateral periodontal (correct)
  • Fissural cysts
  • Calcifying Odontogenic
  • Glandular odontogenic
  • What type of cyst can grow to large dimensions if left untreated and usually appears as a well-circumscribed periapical radiolucency?

    <p>Periapical cyst</p> Signup and view all the answers

    Which epithelium serves as the cellular covering of internal and external body surfaces, including the lining of vessels and small cavities?

    <p>Epithelium - the cellular covering of internal and external body surfaces, including the lining of vessels and small cavities</p> Signup and view all the answers

    Which cyst may result in bleeding into the cystic space, causing it to appear purple or blue in color?

    <p>Vascular FCT</p> Signup and view all the answers

    What is the most common location for the Gingival Cyst of the Adult?

    <p>Facial/buccal aspect of mandibular canine/premolar area</p> Signup and view all the answers

    Which cyst represents the intrabony counterpart of the gingival cyst of the adult?

    <p>Lateral Periodontal Cyst</p> Signup and view all the answers

    Which cyst is unlikely to recur and is often removed by simple surgical excision?

    <p>Gingival Cyst of the Adult</p> Signup and view all the answers

    Which cyst is characterized by dome-like swellings up to 5 mm in diameter, often with a bluish or grayish hue?

    <p>Gingival Cyst of the Adult</p> Signup and view all the answers

    Which of the following is NOT a common radiographic finding associated with inflammatory odontogenic cysts?

    <p>Multilocular appearance</p> Signup and view all the answers

    Which odontogenic cyst exhibits features of glandular differentiation within the epithelium?

    <p>Glandular Odontogenic Cyst</p> Signup and view all the answers

    What is the most common age group for the presentation of a paradental cyst?

    <p>3rd - 6th decades</p> Signup and view all the answers

    Which odontogenic cyst can cross the midline and presents as a uni- or multilocular radiolucency with a well-defined corticated border?

    <p>Glandular Odontogenic Cyst</p> Signup and view all the answers

    Which of the following is characteristic of a dentigerous cyst?

    <p>Demonstrates downward proliferation and anastomosis of rete pegs in inflamed cases</p> Signup and view all the answers

    Which odontogenic cyst expresses Ki-67, overexpression of Bcl-2, overexpression of MMP's 2 and 9, and mutation of PTCH?

    <p>Odontogenic Keratocyst</p> Signup and view all the answers

    What is the recommended treatment for an eruption cyst?

    <p>Tooth extraction unnecessary</p> Signup and view all the answers

    Which odontogenic cyst has a distinct histologic pattern and more aggressive biologic behavior than conventional odontogenic cysts?

    <p>Odontogenic Keratocyst</p> Signup and view all the answers

    What is a rare occurrence associated with odontogenic cysts that is thought to be 1-2% of all oral cavity carcinomas?

    <p>Carcinoma arising in odontogenic cyst</p> Signup and view all the answers

    Which odontogenic cyst is considered a variant of lateral periodontal cyst and shows a grape-like cluster of small individual cysts?

    <p>Botryoid Odontogenic Cyst</p> Signup and view all the answers

    Which medication inhibits the sonic hedgehog pathway by binding smoothened (SMO)?

    <p>Vismodegib</p> Signup and view all the answers

    What is the typical radiographic appearance of calcifying odontogenic cyst (COC)?

    <p>Mixed radiolucent/radiopaque lesion</p> Signup and view all the answers

    What is the mean age of presentation for dentinogenic ghost cell tumor?

    <p>30 years</p> Signup and view all the answers

    What is a characteristic histological feature of calcifying odontogenic cyst (COC)?

    <p>Presence of ghost cells</p> Signup and view all the answers

    Which term is used to describe a cyst in a particular anatomic location, but is not a diagnosis?

    <p>Globulomaxillary cyst</p> Signup and view all the answers

    Which characteristic histologic finding is used to diagnose Odontogenic Keratocyst (OKC)?

    <p>Keratin scales in the cyst lumen appearing as a creamy paste-like substance</p> Signup and view all the answers

    What is a reason for the increased risk of recurrence of Odontogenic Keratocyst (OKC)?

    <p>Presence of satellite or 'daughter' cysts in the connective tissue wall</p> Signup and view all the answers

    Which treatment option is NOT typically associated with Odontogenic Keratocyst (OKC)?

    <p>Medications targeted to PTCH</p> Signup and view all the answers

    What is a characteristic syndrome finding of Nevoid Basal Cell Carcinoma Syndrome?

    <p>Multiple intracranial calcifications of the falx cerebri</p> Signup and view all the answers

    What is a characteristic feature of skin tumors present in Nevoid Basal Cell Carcinoma Syndrome?

    <p>Ulcerated and umbilicated appearance resembling rodent tumors</p> Signup and view all the answers

    Which cyst is most commonly associated with pain or drainage?

    <p>Nasopalatine Duct Cyst</p> Signup and view all the answers

    Which cyst has a radiographic appearance resembling a 'heart' shape?

    <p>Nasopalatine Duct Cyst</p> Signup and view all the answers

    Which cyst is thought to represent odontogenic cysts or tumors?

    <p>Median Palatine Cyst</p> Signup and view all the answers

    Which cyst is characterized by a gross appearance resembling a 'blood soaked sponge'?

    <p>Aneurysmal Bone Cyst</p> Signup and view all the answers

    Which cyst is not within the bone but is in the sinus?

    <p>Antral Pseudocyst</p> Signup and view all the answers

    Which cyst is considered a form of teratoma and can be found anywhere in the oral cavity?

    <p>Dermoid Cyst</p> Signup and view all the answers

    Which cyst has a cavity lined by stratified squamous epithelium with a granular layer and abundant keratin on the epithelial surface and in the lumen?

    <p>Epidermoid Cyst</p> Signup and view all the answers

    Which cyst feels doughy or rubbery upon palpation and has a histological appearance similar to skin with adnexal structures in the cyst wall?

    <p>Dermoid Cyst</p> Signup and view all the answers

    Which cyst is the most common developmental cyst of the neck and develops from epithelial remnants of the tract which forms when the thyroid anlage descends into?

    <p>Thyroglossal Duct Cyst</p> Signup and view all the answers

    Which cyst is an asymptomatic focal concavity of the cortical bone on the lingual aspect of the mandible, believed to be developmental in origin?

    <p>Stafne Bone Cyst</p> Signup and view all the answers

    Study Notes

    Cyst Characteristics

    • A keratocyst is essentially the same histologically as squamous epithelial lined cysts.
    • A periapical cyst typically appears as a well-circumscribed periapical radiolucency with widening of the PDL space and/or loss of lamina dura.
    • A dentigerous cyst is a central (within bone) lesion.
    • A dentigerous cyst can grow to large dimensions if left untreated and usually appears as a well-circumscribed periapical radiolucency.

    Epithelial Characteristics

    • Squamous epithelium serves as the cellular covering of internal and external body surfaces, including the lining of vessels and small cavities.

    Cyst Appearance

    • A hemorrhagic cyst may result in bleeding into the cystic space, causing it to appear purple or blue in color.
    • A gingival cyst of the adult typically appears in the most common location of the anterior mandible.
    • The gingival cyst of the adult is the counterpart of the lateral periodontal cyst.

    Cyst Behavior

    • A dentigerous cyst is unlikely to recur and is often removed by simple surgical excision.
    • A gingival cyst of the adult is characterized by dome-like swellings up to 5 mm in diameter, often with a bluish or grayish hue.

    Radiographic Findings

    • A periapical cyst is not associated with a radiolucent lesion surrounded by a radiopaque border.
    • A calcifying odontogenic cyst (COC) exhibits features of glandular differentiation within the epithelium.
    • A paradental cyst typically presents in the age group of 10-20 years.
    • An odontogenic keratocyst (OKC) can cross the midline and presents as a uni- or multilocular radiolucency with a well-defined corticated border.

    Treatment

    • The recommended treatment for an eruption cyst is surgical excision.
    • Vismodegib is a medication that inhibits the sonic hedgehog pathway by binding smoothened (SMO).

    Calcifying Odontogenic Cyst (COC)

    • The typical radiographic appearance of COC is a uni- or multilocular radiolucency with a well-defined corticated border.
    • The mean age of presentation for dentinogenic ghost cell tumor is 34 years.
    • A characteristic histological feature of COC is the presence of ghost cells.

    Odontogenic Keratocyst (OKC)

    • The term "keratocyst" is used to describe a cyst in a particular anatomic location, but is not a diagnosis.
    • A characteristic histologic finding used to diagnose OKC is the presence of a parakeratinized stratified squamous epithelium.
    • A reason for the increased risk of recurrence of OKC is the presence of satellite cysts.
    • Marsupialization is not typically associated with OKC treatment.

    Nevoid Basal Cell Carcinoma Syndrome

    • A characteristic syndrome finding of Nevoid Basal Cell Carcinoma Syndrome is the presence of multiple odontogenic keratocysts.
    • A characteristic feature of skin tumors present in Nevoid Basal Cell Carcinoma Syndrome is the presence of basal cell carcinomas.

    Other Cysts

    • A buccal bifurcation cyst is most commonly associated with pain or drainage.
    • A nasopalatine cyst has a radiographic appearance resembling a 'heart' shape.
    • A nasoalveolar cyst is thought to represent odontogenic cysts or tumors.
    • A globulomaxillary cyst is characterized by a gross appearance resembling a 'blood soaked sponge'.
    • A nasolabial cyst is not within the bone but is in the sinus.
    • A dermoid cyst is considered a form of teratoma and can be found anywhere in the oral cavity.
    • A dermoid cyst has a cavity lined by stratified squamous epithelium with a granular layer and abundant keratin on the epithelial surface and in the lumen.
    • An epidermoid cyst feels doughy or rubbery upon palpation and has a histological appearance similar to skin with adnexal structures in the cyst wall.
    • A thyroglossal duct cyst is the most common developmental cyst of the neck and develops from epithelial remnants of the tract which forms when the thyroid anlage descends into the neck.
    • A Stafne cyst is an asymptomatic focal concavity of the cortical bone on the lingual aspect of the mandible, believed to be developmental in origin.

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    Test your knowledge about the characteristics, diagnosis, and treatment of Nasopalatine Duct Cysts, also known as incisive canal cysts. Explore the common features, presentation, and management of this oral cavity cyst.

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