Nasal Immunity and NALT in Vertebrates
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Questions and Answers

What is found in the rainbow trout nasal cavity lining?

  • Adenoids
  • Tonsils
  • Lymphoepithelium (correct)
  • Scattered immune cells
  • What do lymphocyte aggregates in the rainbow trout nasal cavity contain?

  • 50% CD4+, 40% IgM+, 5% CD8α+, and 5% IgT+ lymphocytes (correct)
  • 90% CD4+ and 10% CD8α+ lymphocytes
  • 30% CD4+, 30% IgM+, 30% CD8α+, and 10% IgT+ lymphocytes
  • 60% CD8α+ and 40% IgT+ lymphocytes
  • What is the function of organized NALT (O-NALT) in mammals?

  • Mounts innate immune responses
  • Supports affinity maturation of the adaptive immune response in the nasopharyngeal cavity (correct)
  • Triggers expansions of B and T cells
  • Secretes mucus in the nasal cavity
  • What triggers expansions of B and T cells in rainbow trout upon i.n. vaccination?

    <p>Live attenuated infectious hematopoietic necrosis virus</p> Signup and view all the answers

    Which type of lymphocytes undergo proliferation and apoptosis within O-NALT upon prime but not boost i.n. vaccination in rainbow trout?

    <p>IgM+ B cells</p> Signup and view all the answers

    What is the main difference between NALT in teleost fish and O-NALT in mammals?

    <p>Absence of lymphoepithelium vs. presence of lymphoepithelium</p> Signup and view all the answers

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