Nanotechnology in Medicine
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Nanotechnology in Medicine

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Questions and Answers

What type of nanoparticles are used for the delivery of therapeutics in this study?

  • Liposomes
  • Inorganic Nanoparticles (NPs)
  • Phage-mimetic nanoparticles
  • Solid Lipid Nanoparticles (SLNP) (correct)

    • Which method is mentioned for the estimation of drug transfer potential?

  • Electroporation
  • F-actin AFM (correct)
  • Microscopy analysis
  • Solvent diffusion method

    • What does phage-mimetic nanoparticles facilitate in drug delivery?

  • Combining with organic compounds
  • Inhibiting virus-based mechanisms
  • Loading drugs and transferring foreign genes (correct)
  • Transferring bacterial genes only

    • Which photosensitizer is mentioned in the study related to SLNP?

    <p>Cyanine IR-780</p> Signup and view all the answers

    What characteristic is unique to the drugs carried by filamentous bacteriophage?

    <p>They can be genetically designed to load drugs</p> Signup and view all the answers

    What type of diseases can be targeted using the mentioned phage-based delivery system?

    <p>Both bacterial and viral diseases</p> Signup and view all the answers

    Which technique is mentioned for compressing nanoparticles during the drug delivery process?

    <p>Electroporation</p> Signup and view all the answers

    What can be bound to phage for enhancing drug transfer according to the study?

    <p>Definite peptides or antibodies</p> Signup and view all the answers

    What is a primary advantage of using mesoporous silica nanoparticles (MSNs) in drug delivery systems?

    <p>They are affordable and effective.</p> Signup and view all the answers

    Which type of polymer was used for loading siRNA in the MSNs mentioned?

    <p>Poly(ethylene-imine)</p> Signup and view all the answers

    In what year were chitosan nanoparticles highlighted for drug delivery to targeting sites?

    <p>2019</p> Signup and view all the answers

    Which of the following drug delivery methods is NOT specifically mentioned in relation to chitosan nanoparticles?

    <p>Transdermal drug delivery</p> Signup and view all the answers

    What characteristic of MSNs contributes to their effectiveness in drug delivery systems?

    <p>Surface hyper-branching</p> Signup and view all the answers

    What is a significant disadvantage typically associated with viral vectors in drug delivery?

    <p>Longer time to deliver drugs</p> Signup and view all the answers

    What is the primary function of polyamidoamine nanoparticles in drug delivery?

    <p>To enhance drug targeting and delivery to specific sites</p> Signup and view all the answers

    What method is used to determine particle size in the context of nanoparticles mentioned?

    <p>Dynamic light scattering (DLS)</p> Signup and view all the answers

    Which delivery system is indicated to involve both chitosan nanoparticles and MSNs?

    <p>Pulmonary drug delivery</p> Signup and view all the answers

    How do polyamidoamine nanoparticles improve the therapy of doxorubicin?

    <p>They enhance the solubility and decrease toxicity</p> Signup and view all the answers

    Which of the following is a characteristic of nanocarrier systems?

    <p>They can enhance the blood half-life of the drug</p> Signup and view all the answers

    What role do fluorescence-assisted techniques play in the use of polyamidoamine nanoparticles?

    <p>They are used for targeting sites and characterization</p> Signup and view all the answers

    What is one application of polyamidoamine nanoparticles apart from drug delivery?

    <p>Acting as imaging agents in diagnostics</p> Signup and view all the answers

    Which technique is NOT used in the characterization of polyamidoamine nanoparticles?

    <p>Gas chromatography</p> Signup and view all the answers

    What key benefit does the union of doxorubicin and polymers provide?

    <p>Enhanced targeting and reduced side effects</p> Signup and view all the answers

    Which drug is specifically mentioned as being delivered via polyamidoamine nanoparticles?

    <p>Anti-malarial drugs</p> Signup and view all the answers

    What is a primary characteristic of an optimal drug delivery system (DDS)?

    <p>Effectiveness in targeting lesions</p> Signup and view all the answers

    What role do polymeric nanoparticles play in Alzheimer's disease treatment?

    <p>They enhance drug absorption in the brain.</p> Signup and view all the answers

    Which of the following is NOT a strategy used in drug delivery to the brain?

    <p>Standard oral administration</p> Signup and view all the answers

    How can nanocarrier systems enhance drug delivery through the BBB?

    <p>Through interaction with endothelial micro vessel cells</p> Signup and view all the answers

    What is the significance of nose-to-brain delivery in drug administration?

    <p>It provides a direct pathway to the brain.</p> Signup and view all the answers

    Which of the following describes a common challenge in treating brain diseases?

    <p>Drugs poorly reach brain tissues.</p> Signup and view all the answers

    What nanocarrier type is specifically mentioned as being used for the treatment of Alzheimer's disease?

    <p>Solid lipid nanoparticles</p> Signup and view all the answers

    Which component is critical for the success of an intranasal drug delivery system?

    <p>Interaction with olfactory nerve fibers</p> Signup and view all the answers

    What is the role of polymeric nanoparticles in the treatment of brain diseases?

    <p>They aid in drug delivery within the brain.</p> Signup and view all the answers

    Which of the following is NOT a disadvantage of nanomedicines?

    <p>High drug loading capacity</p> Signup and view all the answers

    What is a key characteristic of Piperine-loaded SLNPs?

    <p>Widely examined with fewer side effects</p> Signup and view all the answers

    Which delivery system is used to cross the blood-brain barrier and treat Alzheimer's disease?

    <p>Folic-acid-loaded liposomes</p> Signup and view all the answers

    How does Tacrine-loaded polymeric nanoparticles benefit drug delivery?

    <p>They allow targeted drug release.</p> Signup and view all the answers

    What disadvantage is associated with Beta-Asarone-loaded nanoemulsions?

    <p>Instant drug release</p> Signup and view all the answers

    What is a notable advantage of folic acid-loaded liposomes?

    <p>They exhibit high bioavailability.</p> Signup and view all the answers

    Which of the following materials is injected intraperitoneally to prevent plaque formation?

    <p>Piperine</p> Signup and view all the answers

    What primary advantage do nanomedicines have when treating brain illnesses?

    <p>They are biocompatible and have lower costs.</p> Signup and view all the answers

    What is a common difficulty faced by folic acid-loaded liposomes?

    <p>Difficulty in binding with lipids.</p> Signup and view all the answers

    Study Notes

    Nanotechnology in Medicine

    • Polyamidoamine nanoparticles can be used to deliver anti-malarial drugs.
    • Polyamidoamine nanoparticles improve drug solubility, enhance blood half-life, reduce toxicity, and increase targeting.
    • Solid lipid nanoparticles (SLNPs) can deliver drugs by solvent diffusion.
    • Electroporation can be used to deliver drugs to colon cancer cells.
    • Filamentous bacteriophages can be used as a drug delivery system, as they can carry drugs and genetic material.
    • Mesoporous silica nanoparticles (MSNs) are widely used for drug delivery to the brain.
    • Chitosan nanoparticles are used as a drug delivery system to target various sites in the body.
    • The blood-brain barrier poses a challenge for drug delivery to the brain.
    • Intranasal drug delivery is an option for treating brain diseases.
    • Nanotechnology is used to treat Alzheimer’s disease, Parkinson’s disease, and other brain diseases.
    • Polymeric nanoparticles, liposomes, nanoemulsions, and SLNPs are used to deliver drugs to the brain.
    • Nanomedicine's advantages: prolonged drug retention in the brain, biocompatibility, cost-effectiveness, controlled drug release, and targeted delivery.
    • Nanomedicine's disadvantages: slow degradation, potential toxicity, and low drug loading capacity.

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