N-Linked Glycoproteins and GPI Anchors

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Questions and Answers

Which group is the GPI anchor composed of?

  • Phosphatidylinositol and a fatty acid
  • Phosphatidylinositol and an ethanolamine phosphate
  • Phosphatidylinositol and a carbohydrate-containing linker (correct)
  • Phosphatidylinositol and a mature protein

What is the role of proteins containing a GPI anchor?

  • To attach to the C-terminus of a protein
  • To anchor the protein to the cell membrane
  • To undergo posttranslational modification
  • To play key roles in a wide variety of biological processes (correct)

How is the GPI anchor attached to a protein?

  • Through an ethanolamine phosphate bridge (correct)
  • Through a mature protein
  • Through a fatty acid
  • Through a carbohydrate-containing linker

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