Myopathy and NMJ Lesions

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16 Questions

What is the primary characteristic of myopathy?

Fatigue

Which type of myopathy is associated with exercise intolerance and muscle atrophy?

Hypothyroid myopathy

What is the most common 'negative' symptom reported by a patient with muscle disease?

Weakness

Which type of myopathy is commonly associated with localized contraction of an entire muscle group, individual single muscle, or select muscle fibers?

Myotonic disorders

Which type of myopathy is specifically associated with continuous, involuntary, painful muscle contractions?

Myotonic disorders

Which type of myopathy is commonly associated with muscle pain and is not common in most other muscle diseases?

Inflammatory myopathies

What is the common symptom of exercise intolerance?

Fatigue

Which type of muscular hypertrophy refers to an increase in myofibrils?

Myofibrillar

What is the phenomenon of impaired relaxation of muscle after forceful voluntary contraction called?

Myotonia

Which type of muscular dystrophy is a lethal progressive pediatric muscle disorder?

Duchene muscular dystrophy

What causes muscle wasting and weakness that makes it hard to relax the muscles after gripping or holding something?

Myotonic dystrophy (MD)

What is the most common kind of muscular dystrophy in adults?

Myotonic dystrophy (MD)

What is the common cause of myotonia?

Repetitive depolarization of muscle membrane

Which gene mutation causes type 1 myotonic dystrophy (DM1)?

DMPK gene

What is the primary cause of premature demise in individuals affected by Duchene muscular dystrophy (DMD)?

Respiratory and/or cardiac failure

What is the invariable result of any disturbance in the biochemical pathways that support muscle contraction?

Fatigue

Learn about myopathy, including its definition, types, diagnosis, and treatment, as well as neuromuscular junction lesions. This quiz covers the basics of muscle disorders affecting skeletal muscle structure, metabolism, and ion channel function.

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