Mycobacterium Tuberculosis Pathogenesis
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Questions and Answers

Mycobacterium tuberculosis produces no exotoxins and does not contain ______ in its cell wall.

endotoxin

M. tuberculosis produces two proteins that appear to play a role in ______: 1- One is tuberculosis necrotizing toxin (TNT); resulting in death of the infected macrophage.

pathogenesis

The other is early secreted antigen-6 (ESAT-6), a protein that reduces the innate immune response by reducing ______ production, thereby enhancing the virulence of the organism.

gamma interferon

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