30 Questions
What is the characteristic facial expression in a patient with MG?
A snarling expression
In patients with MG, what is the most noticeable effect of weakness in chewing?
Weakness after prolonged effort
What is the characteristic of speech in patients with MG?
A nasal quality
What percentage of patients with MG experience generalized weakness?
85%
What is the significance of weakness remaining restricted to the extraocular muscles for 3 years?
It will not become generalized
What is the diagnostic significance of anti-AChR antibodies?
They are virtually diagnostic of MG
What percentage decrease in amplitude of evoked muscle action potentials is seen in myasthenic patients during repetitive nerve stimulation?
10-15%
What is the primary purpose of administering edrophonium (Tensilon) in myasthenia gravis patients?
To diagnose myasthenia gravis
What is the term for the test that involves inserting a fine wire electrode through the skin and into a muscle to test a single muscle fiber?
Single-fiber electromyography (EMG)
What is the enzyme that is inhibited by certain drugs to improve muscle strength in myasthenia gravis patients?
Acetylcholinesterase (AChE)
What is the term for the antibody that may be present in some seronegative myasthenia gravis patients?
Muscle-specific kinase (MuSK) antibody
Which of the following is a characteristic of bulbar weakness in myasthenia gravis?
Dysphagia
What is a common finding in normal individuals undergoing repetitive nerve stimulation?
No change in the amplitude of evoked muscle action potentials
What is the effect of anticholinesterase medication on myasthenic patients?
At least partial improvement in most patients
What is the primary treatment for myasthenia gravis when symptomatic treatment is not effective?
Immunosuppressive agents
What is a possible side effect of anticholinesterase medication?
Muscarinic side effects such as diarrhea
What is used to treat gastrointestinal symptoms caused by anticholinesterase medication?
Atropine/diphenoxylate or loperamide
What is a characteristic of autonomic findings in myasthenia gravis?
Dilated or poorly reactive pupils
What percentage of patients with MG develop hyperthyroidism?
3-8%
What is the primary cause of Lambert-Eaton myasthenic syndrome?
Autoantibodies against calcium channels
Which of the following is a common finding in patients with LEMS?
Depressed or absent reflexes
What is the primary mechanism of action of the botulinum toxin?
Interfering with the release of acetylcholine
Why are PFTs valuable in patients with MG?
To monitor respiratory function
What is the most common type of cancer associated with LEMS?
Lung carcinoma
What is the estimated percentage of patients who experience improvement with treatment?
70%
What is a rare but serious adverse reaction associated with treatment?
Aseptic meningitis
What is the primary cause of myasthenic crisis?
Intercurrent infection
In what type of unit should treatment for myasthenic crisis take place?
Intensive care unit
What is a common therapeutic approach to hasten recovery in myasthenic crisis?
Plasmapheresis or IVIg
Why should anticholinesterase drugs be temporarily stopped in myasthenic crisis?
To rule out cholinergic crisis
This quiz covers the symptoms of Myasthenia Gravis (MG), including early signs such as cranial muscle weakness, facial weakness, and speech disturbances. It also explores how MG affects limb muscles and other parts of the body. Test your knowledge of MG symptoms!
Make Your Own Quizzes and Flashcards
Convert your notes into interactive study material.
Get started for free
