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My Virology Notes: Orthomyxoviridae and Influenza

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My Virology Notes: Orthomyxoviridae and Influenza

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Questions and Answers

What is the characteristic of the Orthomyxoviridae genome?

Segmented single-stranded RNA (correct)

Single-stranded RNA

Non-segmented double-stranded RNA

Double-stranded RNA

What is the function of Hemagglutination in the influenza virus?

Penetration and budding

Absorption and attachment (correct)

Adaptive mutation

Reassortment of genomes

What is the basis for distinguishing between the three major antigenic types of Orthomyxoviridae?

Antigenic differences in the polymerase protein

Antigenic differences in the hemagglutinin protein

Antigenic differences in the neuraminidase protein

Antigenic differences in the matrix protein (M) and nucleoprotein (NP) (correct)

Which type of influenza virus is antigenic shift exclusive to?

Influenza A only Signup and view all the answers

What is the primary method for diagnosing influenza A?

Cell culture with hemadsorption using guinea pig red blood cells Signup and view all the answers

What is the result of antigenic drift?

Minor change in antigenic structure Signup and view all the answers

What is the characteristic of Influenza C?

Causes mild form of influenza Signup and view all the answers

What is the mechanism of antigenic shift that involves the combination of different influenza viruses?

Genetic reassortment Signup and view all the answers

What is the treatment for influenza A?

Supportive care and Amantadine Signup and view all the answers

What is the type of influenza that occurred in 1957-1958?

Asian Flu Signup and view all the answers

Why is testing for Influenza C not routinely requested?

The virus is not frequently detected Signup and view all the answers

What is the outcome of antigenic shift in the influenza virus?

Pandemics and epidemics Signup and view all the answers