My Virology Notes: Orthomyxoviridae and Influenza
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Questions and Answers

What is the characteristic of the Orthomyxoviridae genome?

  • Segmented single-stranded RNA (correct)
  • Single-stranded RNA
  • Non-segmented double-stranded RNA
  • Double-stranded RNA

What is the function of Hemagglutination in the influenza virus?

  • Penetration and budding
  • Absorption and attachment (correct)
  • Adaptive mutation
  • Reassortment of genomes

What is the basis for distinguishing between the three major antigenic types of Orthomyxoviridae?

  • Antigenic differences in the polymerase protein
  • Antigenic differences in the hemagglutinin protein
  • Antigenic differences in the neuraminidase protein
  • Antigenic differences in the matrix protein (M) and nucleoprotein (NP) (correct)

Which type of influenza virus is antigenic shift exclusive to?

<p>Influenza A only (B)</p> Signup and view all the answers

What is the primary method for diagnosing influenza A?

<p>Cell culture with hemadsorption using guinea pig red blood cells (D)</p> Signup and view all the answers

What is the result of antigenic drift?

<p>Minor change in antigenic structure (A)</p> Signup and view all the answers

What is the characteristic of Influenza C?

<p>Causes mild form of influenza (D)</p> Signup and view all the answers

What is the mechanism of antigenic shift that involves the combination of different influenza viruses?

<p>Genetic reassortment (A)</p> Signup and view all the answers

What is the treatment for influenza A?

<p>Supportive care and Amantadine (C)</p> Signup and view all the answers

What is the type of influenza that occurred in 1957-1958?

<p>Asian Flu (B)</p> Signup and view all the answers

Why is testing for Influenza C not routinely requested?

<p>The virus is not frequently detected (C)</p> Signup and view all the answers

What is the outcome of antigenic shift in the influenza virus?

<p>Pandemics and epidemics (B)</p> Signup and view all the answers

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