My Virology Notes: Orthomyxoviridae and Influenza

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12 Questions

What is the characteristic of the Orthomyxoviridae genome?

Segmented single-stranded RNA

What is the function of Hemagglutination in the influenza virus?

Absorption and attachment

What is the basis for distinguishing between the three major antigenic types of Orthomyxoviridae?

Antigenic differences in the matrix protein (M) and nucleoprotein (NP)

Which type of influenza virus is antigenic shift exclusive to?

Influenza A only

What is the primary method for diagnosing influenza A?

Cell culture with hemadsorption using guinea pig red blood cells

What is the result of antigenic drift?

Minor change in antigenic structure

What is the characteristic of Influenza C?

Causes mild form of influenza

What is the mechanism of antigenic shift that involves the combination of different influenza viruses?

Genetic reassortment

What is the treatment for influenza A?

Supportive care and Amantadine

What is the type of influenza that occurred in 1957-1958?

Asian Flu

Why is testing for Influenza C not routinely requested?

The virus is not frequently detected

What is the outcome of antigenic shift in the influenza virus?

Pandemics and epidemics

Test your knowledge of Orthomyxoviridae, a virus family with a segmented genome, and its characteristics, including antigenic types and the diseases it causes. Focus on Influenza and its diagnosis.

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